Recent News
Read ArticleA prospective, multicenter study from Spain has demonstrated higher rates of mortality and serious infection in rheumatoid arthritis–associated interstitial lung disease (RA-ILD) patients.
Lupus Accelerating Breakthroughs Consortium Partners with FDA
EurekAlert!
The Lupus Research Alliance (LRA), founder and administrator of the Lupus Accelerating Breakthroughs Consortium (Lupus ABC), announced today at the Consortium’s first anniversary meeting an expanded partnership with the U.S. Food and Drug Administration (FDA) with the inclusion of the Center for Biologics Evaluation and Research (CBER).
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GPA Management in 2024
https://t.co/ASmIAS4XrT https://t.co/t4AlNInuzG
Dr. John Cush @RheumNow ( View Tweet)
Peripheral dermatomes & key muscles of the most important lumbosacral
nerve roots. However, keep in mind that the muscles also receive contributions from other nerves (e.g., the extensor digitorum longus is innervated mainly by L5, but also from L4 and S1). https://t.co/auXMMddUIh
Dr. OMID BANDARCHI @OBandarchi ( View Tweet)
#peritendinous #ultrasoundguidedinjection with #osteniltendon for Tendinopathy of the #tibialisposterior #tendon #mskus #pocus #pocushub #GElogiqE10r3 https://t.co/8qe1G27tAl
Dr Jörg Dünkel @SportklinikBern ( View Tweet)
ICYMI: Vasculitis Pearls
https://t.co/7z6b0Wj37X https://t.co/PHlOvFG9qQ
Dr. John Cush @RheumNow ( View Tweet)
Biopsy Results in Sjogren's Syndrome Save
A prospective study from the Netherlands analyzed the comparative value of simultaneous labial and parotid salivary gland biopsies performed in patients with sicca complaints and suspected SjD.
https://t.co/meJgf7dI8N https://t.co/zHg6SgiufS
Dr. John Cush @RheumNow ( View Tweet)
FDA has approved a ustekinumab biosimilar (ustekinumab-aekn; AKA Selardsi), made by Teva & Alvotech, for the treatment of moderate to severe plaque psoriasis (PsO) and active psoriatic arthritis (PsA) in both adults and pediatric pts.https://t.co/ZXvFjjH7Qt https://t.co/7FJKxSVAgL
Dr. John Cush @RheumNow ( View Tweet)
#RNL2024 @philseo: I now give Tociliizumab for nearly all patients with GCA
GiACTA shows we weren't doing well enough w/steroid monotherapy
GiACTA shows dosing frequency does not make big diff in new diagnosis, but makes a diff in relapsing disease https://t.co/khJe0bwKXy
Links:
Dr. John Cush @RheumNow ( View Tweet)
GCA pts on Toci mgmt
#RNL2024 @RheumNow
@philseo rec's increase interval to q4w before d/c TCZ
Limited evidence from this from study of 17 patients where weaned off TCZ. Hopes to capture pts with mild flares with tapering dose.
MAGICA trial will study abrupt d/c v wean dose
Dr. John Cush @RheumNow ( View Tweet)
BSR Guideline on Management of Sjogren’s Syndrome
Sjögren disease (SD) is the most common of all autoimmune disease, yet little is know of its etiology and there are insufficent interventions for those affected with mucosal or systemic manifestations.
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Burnout or Retire
Dr. Jack Cush reviews the news and journal reports from this past week on https://t.co/V10S4oVFsv. Is it time to worry about burnout and those who are leaving healthcare?
https://t.co/p8ek7A8HAk https://t.co/nH5fDywLic
Dr. John Cush @RheumNow ( View Tweet)
PNAS: Autoimmunity against MDA5 induces fibrotic ILD in mice. In this murine model of dermatomyositis, treatment with either anti-CD4 or anti-IL-6 receptor antibody ameliorated the MDA5-induced fibrotic ILD. https://t.co/CahyGfTn4g https://t.co/lfpdgEvGmx
Links:
Dr. John Cush @RheumNow ( View Tweet)
ICYMI: Sex Disparities in PsA/SpA
https://t.co/55zwjR8mNR https://t.co/fhhekNpHVA
Dr. John Cush @RheumNow ( View Tweet)
ILD Onset in MDA-5 Dermatomyositis
MDA5 antibody-positive DM is a rare, aggressive and progressive subtype of DM. Its' severity is dependent on the development of progressive ILD, manifesting as either RPILD and CILD.
https://t.co/08wAYj06DH https://t.co/TQWHGR27O9
Dr. John Cush @RheumNow ( View Tweet)
ICYMI: Vasculitis Pearls
Once again RheumNow Live 2024 really delivered with high impact learning packed into short sessions. As someone with an interest in vasculitis it was fantastic to see four of my favorite speakers in the Vasculitis Mavens and STEP talks. They gave us what we really want from these talks – personal opinions and approaches that go beyond the guidelines. They really dropped a selection of pearls on us and I wanted to share a few of these with you
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Biopsy Results in Sjogren's Syndrome
A prospective study from the Netherlands analyzed the comparative value of simultaneous labial and parotid salivary gland biopsies performed in patients with sicca complaints and suspected Sjogren's syndrome (SjD).
World Congress on OP, OA & MSK Disorders
Bone and musculoskeletal disease researchers and physicians from around the world will meet today in London for the opening of the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
https://t.co/kzvWD4Rmki https://t.co/PJQREsJO9v
Dr. John Cush @RheumNow ( View Tweet)
Neuropsychiatric SLE - 2/3 Improved at 12 Months
The management and outcomes of neuropsychiatric systemic lupus erythematosus (NPSLE) can be challenging as there is limited data.
https://t.co/p0GEtkUTdt https://t.co/EZhjH6PxWQ
Dr. John Cush @RheumNow ( View Tweet)
TNFi mAbs, JAKi, –IL-17 are protective against Anterior Uveitis (AU) in AxSpA. Metanalysis of 44 RCTs shows AU IR:
- TNF mAbs: 4.1
- etanercept 5.4
- IL-17i: 2.8
- JAKi: 1.5
- placebo: 10.8 https://t.co/sxqCXkD0up https://t.co/XWXUPmCtZr
Dr. John Cush @RheumNow ( View Tweet)
Of 375 #Gout pts D/C pegloticase after a median of 8 infusions (taken 112days (max 1,240d). Only 73% had SUA < 6 during pegloticase. After D/C 84% went on ULT (63% allopurinol; 34% febuxostat; after mean 92d); after ≥ 30 days), 51% achieved SUA < 6 https://t.co/unkvt1whrs https://t.co/DgVpBgKXcm
Dr. John Cush @RheumNow ( View Tweet)
From the blog
Over the last few decades, Japanese workers were collapsing dead at their desks or committing suicide due to the high stress stemming from their jobs; Japan coined this phenomenon, “Karoshi.” In 2021, the World Health Organization and International Labour Organization issued a warning: working 55+ hours a week is a serious health hazard and increases the risk for death from heart disease and stroke. But since the pandemic, I see many colleagues working hard at the expense of their health, family life, mental and emotional well-being. I never thought I would be burned out because I had passion for my job.
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Podcasts
Tuesday Night Rheumatology- Vasculitis Mavens
GPA Management In 2024 - Dr. Anisha Dua
Burnout Or Retire (4.12.2024)
PsA Faculty Panel Q&A - featuring Drs. A Ogdie,A Armstrong,L Eder; moderated by Dr. A. Kavanaugh
Poster Hall
