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A population based analysis from Israel suggests that giant cell arteritis (GCA) patients may be at increased risk for inflammatory bowel diseases (IBD) mainly target.
This research was based on sporadic reports in the medical literature (http://bit.ly/2pnIPM0)
Claims data analysis of 3938 GCA patients and 21,623 matched controls finds that GCA patients had a significantly increased rates of CD and UC (0.79% vs. 0.12% and 0.84% vs. 0.21%, P-value < .001, respectively) when compared to normal controls.
This GCA and IBD association was negatively correlated with the patients' age; and was more robust in middle-aged (OR = 8.13) than in elderly patients (OR = 3.81).
Such data should influence the medical and GI evaluations of GCA patients suffering from gastrointestinal complaints, especially in middle-aged patients (50-69 years of age). Moreover, age related routine colonoscopy should be strongly encouraged in such GCA patients.