Pregnancy Complications in Primary Sjogren's Save
Sjogren's syndrome is a highly prevalent disorder, affecting women ten times more frequently than men. Although the typical onset follows menopause, a minority of women may develop primary Sjogren’s syndrome (pSS) during child-bearing years.
A new systematic review and meta-analysis has assessed the association between pSS and adverse pregnancy outcomes. Included in this analysis were 544 pSS patients with 1586 pregnancies. The complications studied included spontaneous abortion, stillbirth, neonatal deaths, and intrauterine growth retardation.
The study identified a significantly higher chance of neonatal deaths (pooled odds ratio [OR] = 1.77, 95 % confidence interval [CI] 1.28 to 1.46, p = 0.01) in women with pSS compared to healthy adults.
There was no association seen between pSS and stillbirth, spontaneous or artificial abortions and premature birth.
This report suggests that there is an increased risk of fetal death associated with pSS. The authors call for multidisciplinary care in pSS patients to prevent neonatal deaths and pregnancy complications.
ADD THE FIRST COMMENT
Disclosures
The author has no conflicts of interest to disclose related to this subject
If you are a health practitioner, you may Login/Register to comment.
Due to the nature of these comment forums, only health practitioners are allowed to comment at this time.