Tuesday, 16 Oct 2018

You are here

RheumNow Week in Review – 15 July 2016

Dr. Jack Cush reviews highlights from this week's rheumatology news on RheumNow.com.

  1. FDA Approves Xiidra (Lifitegrast), an LFA-1 agonits for Dry Eyes. 
  2. FDA Arthritis Advisory Committee Votes 26-0 to Recommend Approval of Adalimumab Biosimilar (Amgens ABP-501).  
  3. Sandoz Etanercept Biosimilar (GP-2015) Unanimously (20-0) Voted for Approval by FDA Arthritis Advisory Committee.  
  4.  FDA Says Cryotherapy, not approved, lacks evidence and poses risks.  http://rheumnow.com/content/fda-says-cryotherapy-lacks-evidence-poses-risks
  5. Vagal Stimulation Decreases Proinflammatory Cytokine Production and Rheumatoid Disease Activity.  
  6. Lupus panniculitis appears as indurated nodules/plaques with lipoatrophy, usually over the proximal extremities & trunk. Important to get a deep Biopsy.  Usual treatments include hydroxychloroquine, steroid, dapsone, others reviewed. https://t.co/CJ5uJHxtcF
  7. In 428 SpA pts, BMI (obesity) had no effect on ASDAS. BMI weakly correlates with CRP, other PRO's. https://t.co/FcTfEicYpN
  8. Small study of Bactrim in GPA (Wegeners) shows 25% relapse w/ continued Rx vs 45% relapse with Bactrim withdrawal. https://t.co/IQksnzI5mk
  9. German RABBIT registry study >13K pts shows an increased risk of lower GI perforations with Actemra (2.7/1000PY), with a four fold higher risk than other therapys.  Nearly 25% of such patients died. https://t.co/u9A4TRFMso
  10. Prevalence of gout increasing in EU from 1.7% to 2.5%; in the US to 4%. Gout is becoming epidemic. https://t.co/zSSRbTId73
  11. 100k German RA compared to 500k controls: RA patients were vaccinated more; but more pneumonia hospitalizations were seen in regions with low or no vaccination https://t.co/HxOIIOf0rP
  12. 234 RA patients treated with Rituxan for a mean of 28 mos. Showed a retention rate of 57%. Discontinuatoins were associated with higher age, greater swollen joint counts, lack of concomitant MTX use.  https://t.co/QRLR9mgP84

 

Disclosures: 
The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

RheumNow Week in Review – Four Fingers are Best (10.12.18)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. New info on scleroderma-SLE overlap, nailfold capillaroscopy, Women with SpA, acute gout management and lupus patient in pain who visit the ED.

RheumNow Week in Review – Vitamin D Falls Again (10.4.18)

Dr. Jack Cush reviews the news from the past week on RheumNow.com. 

RheumNow Week in Review – I Wanna New Drug (9.28.18)

Dr. Jack Cush reviews the news from the past week on RheumNow.com, including news on inappropriate opioids, pre-clinical RA treatment, DMARDs in Gout, the decline of arthroscopy, and a pain in the mouth.

CDC: 2017 Record Number of Influenza Deaths

The CDC reports that in 2017, influenza killed and hospitalized more people in the United States than any other year in the last few decades. (Citation Source http://bit.ly/2DBr0TE)

RheumNow Week in Review – RheumNow Live Meeting Announcement (9.21.18)

Dr. Jack Cush reviews the news and updates from the past week on RheumNow.