Wednesday, 21 Aug 2019

You are here

The RheumNow Week in Review – 25 August 2017

The RheumNow Week in Review discusses the past week's news, journal articles and highlights from RheumNow.com. This week's report includes new data on IL-1 and pregnancy, contraceptives and the risk of RA, Calprotectin the biomarker, T2T failing, and the loss of a giant in rheumatology.

  1. Data on IL-1 inhibitors and pregnancy: 11 paternal & 31 maternal (23 Anakinra, 8 Cannakinumab) exposures, mosly live births and only  1 renal agenesis/ectopic neurohypophysis.  https://buff.ly/2wstyyA
  2. 435 Nordic JIA pts, Uveitis found in 20.5%; 90% asympt. Predictors of uveitis were ANA+, AHA+, JIA onset <7yrs in girls, not boys  https://buff.ly/2ise342
  3. Study of 215 RA patients Rx with DMARDs & T2T strategy. Serum Calprotectin shown to be strong biomarker; significantly correlated with ESR, CDAI, US Power doppler, Xray progression https://t.co/82YvTFtcAV
  4. 4666 elderly Canadian RA patients, only 59% were deemed to be adherent to biologic therapy, Nonadherent used more steroids https://t.co/kmEmgmmc4p
  5. 55% Americans take prescription medicine; now more than ever. https://t.co/3ytMXHHhVP
  6. Swedish EIRA study: Oral contraceptive use decreases risk of ACPA+ RA. breast feeding has no effect. Ever/past oral contraceptive users have a decreased risk of ACPA-positive RA (OR=0.84) https://t.co/7p9wpfHBJY
  7. Ironwood announces FDA approval of its combo drug lesinurad/allopurinol (Duzallo) in a 200/300 tablet. Could this be useful? https://t.co/lcUZTieKqg
  8. 30 yoF with non itchy, nonpainful palpable purpura lesions on legs & abdomen on/off for last 8 mos. Patient has Hx of HBV Rx with Tenovir. What would you do next?
  9. Leukocytoclastic vasculitis is most commonly caused by antibiotic use (Cipro, Cefazolin ) https://t.co/I893XN737C
  10. Non-Tuberculous Mycobacterial Infections - Diagnosis and Management for the Rheumatologist
  11. IV Golimumab Shines in Psoriatic Arthritis  
  12. Treat-to-Target a Bust with Rheumatologists   
  13. It's Rheumatoid Arthritis, not the TNF inhibitor, that Drives Lymphoma Risk 
  14. Dr. H. Ralph Schumacher (1933-2017) 
  15. Therapeutic Update: 5 Questions on FDA Hearing for Tofacitinib in PsA 
Disclosures: 
The author has received compensation as an advisor or consultant on this subject

Add new comment

More Like This

RheumNow Podcast – Antibiotics Increase RA Risk (8.16.19)

Dr. Jack Cush reports the news and important journal articles from the past week on RheumNow.com.

RheumNow Podcast – Tricked Up Lupus Criteria (8.9.19)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com, including new SLE criteria, ULT in gout and MSU reductions, IVIG in ANCA vasculitis and non-TNF biologics outperform the TNF inhibitors.

EULAR Recommendations on Large Vessel Vasculitis

Th European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis (LVV) was originally published in 2009. Since then there have been new randomised clinical trials and cohort analyses leading to an update the original recommendations.

RheumNow Podcast – More Than a Spot of Tea (8.2.19)

Dr. Jack Cush reviews the journal articles and news reports from the past week on RheumNow.com: MMP-7 and Myositis-ILD; Post-surgical gout attacks; CV events and testosterone; and a Boxed warning for tofacitinib.

RheumNow Podcast – FDA Hyperactivity (7.26.19)

Dr. Jack Cush reviews the news, journal reports, and FDA releases and deliberations covered this past week on RheumNow.com