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Pregnant women (n=254) with rheumatoid arthritis who enrolled in the MotherToBaby Autoimmune Diseases in Pregnancy Study and who were taking oral glucocorticoids were studied.
- The range of steroid use was 3 to 292 days during pregnancy
- Daily doses ranging from <1 to 60 mg
- Total cumulative dose ranged from 8 to 6225 mg.
After adjustments for disease activity and DMARDs the patterns of higher prednisone dose were associated with shorter gestational length compared with lower dose.