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We're gearing up for Tuesday Night Rheumatology all April long. Register today! Our first TNR takes place 4/2 at 6:30pm ET and will focus on Success in Rheumatoid Arthritis. https://t.co/FeeOdxOiRQ https://t.co/FNoCi6goQS
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
FDA grants orphan drug designation to CAR T-cell therapy for systemic sclerosis https://t.co/KZKSy2sbNk https://t.co/5abz8MeYGK
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
Expert Panel Guidance on Managing Psoriatic Arthritis and Comorbidities An expert panel has published their consensus guidelines for the management of psoriatic arthritis (PsA) and it's comorbidities in the journal Rheumatology. https://t.co/pZjnW4dPxj https://t.co/Si9Gl3WgUx
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
Chronic MSK Pain and Earlier Retirement Frequent musculoskeletal pain is linked with an increased risk of exiting work and retiring earlier, according to a new study published in the journal PLOS ONE. https://t.co/f2skRvd6Dl https://t.co/K8bJjcGOSF
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
1st trimester exposure to Plaquenil is not assoc. w/ risk of congential malformations (MCM). Swedish registry data on 1007 births (453 exposed) & 2500 births (144 exposed) in SLE & RA, respectively. MCM risks in SLE &RA were 3.4-5.7%, no diff betw groups https://t.co/lzbd7AQqy1 https://t.co/AsFYYBQQtm
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
post hoc of the PEXIVAS study 704 participants w/ severe ANCA vasculitis: 92% achieved remission & 23% had relapses (rate 10.3/100PYs)-- Neither plasma exchange nor glucocorticoid tapering regimen impacted relapse risk. https://t.co/UN6RujwZKc https://t.co/MsXKPwp9km
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
Stills pts w/ remission on Tocilizumab who stop TCZ, 50% will relapse in 1 yr. Lower relapse rate w/ longer TCZ use w/ prednisolone lowering. 38/48 AOSD Rx w/ TCZ were in remission after 6 mos. & 12 D/C TCZ - half flared after mean of 5.5 mos.https://t.co/L9XbUX8lXn https://t.co/Z4oixQR2oX
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
Infection and Rituximab-linked Immunoglobulin Deficiency A recent cohort analysis suggests that RTX-induced Ig deficiency was not associated with an increased risk of severe infection in IMID patients. https://t.co/mcEc0FpdpR https://t.co/S2vAXSWlso
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
Case of Delayed Rheum Diagnosis The Washington Post recently published a case titled, "Medical Mysteries: A rolled ankle set this runner down a painful path", which tells the tale of how/why rheums are often not consulted or consulted too late. https://t.co/rusIwlELHu https://t.co/5ePDh4aFDY
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
929 Sjogrens pts from 2 French cohorts subdivided into 3 Groups: 1. BALS: Hi B-cell activity, low Sxs (Dz activity worsened w/ time) 2. HSA: Hi systemic Dz 3. LSAHS: low systemic Dz, Hi Sxs Lymphomas in 3-4% BALS & HSA https://t.co/xI8qjLO8YQ https://t.co/Z2JBuKSUhi
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
French claims data study of Serious infections in 12K #PsA pts Rx w/ biologics (2015-2020) found 367 (3%) w/serious infxn (17/1000Pys). Compared to adalimumab, a signif. lower SIE risk was seen w/ ETN (HR 0.72), & ustekinumab (HR 0.57) https://t.co/oVomnKuYGJ https://t.co/y5DQatFoCa
Dr. John Cush @RheumNow ( View Tweet )
1 month ago
Series of Chronic Cutaneous Lupus responding to anifrolumab. 6 pts (4 DLE, 2 CCLE) betw 37-66 yrs old w/ Dz duration 10.5 yrs, 4 w/ SLE, all refractory to multiple therapies Rx w/ ANIF w/ Skin benefit. 1 developed herpes, 1 had worsening of nephritis https://t.co/XF8uW5xR66 https://t.co/hIJi94uRvr
Dr. John Cush @RheumNow ( View Tweet )
1 month ago