Friday, 16 Feb 2018

Autoimmune/Lupus

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12 Feb 2018 Social Although epratuzumab (anti-CD22 MAb) failed in SLE in two phase III clinical trials, subanalyses show that pts w/ secondary Sjogrens who were SSA positive (7.1% of 1584 enrolled) where more likely to have a BICLA response and decreases in B cells and IgM. https://t.co/n6Woy8rTka
10 Feb 2018 Social Dr Anne Stevens #RWCS - cocaine levamisole causes an autoimmune syndrome with thrombotic vasculopathy with purpura - not vasculitis https://t.co/Q9JxBsCm7g
09 Feb 2018 Social Dr. Hahn on the cost of lupus drug therapy, the last 2(RTX, CTX) are just infusion costs. You need to add drug costs. #RWCS https://t.co/MbD6EzMKAH
09 Feb 2018 Social RT @uptoTate: Questions about steroids for LN. Dr. Hahn #RWCS @RheumNow https://t.co/u5qBTJAbbZ
09 Feb 2018 Social RT @alvinwellsmd: Dr. Bevra Hahn gives a political review of insurance in regards to SLE at the RWCS 2018 https://t.co/B8pPyTPEq2
09 Feb 2018 Social RT @alvinwellsmd: Dr Hahn says it is time to treat to target in SLE! https://t.co/RLIaloMQKI
09 Feb 2018 Social Dr. Bevra Hahn - high vs love dose cytoxan have requested outcomes in lupus nephritis #RWCS 2018 https://t.co/Z32IIQ4Zzm
09 Feb 2018 Social RT @uptoTate: FDA approved Zilretta, extended release triamcinolone, may be a good option for DM patients. Drs. Wells and Troum #RWCS @Rheu…
09 Feb 2018 Social Dr Bevra Hahn survival of renal transplant in lupus is good, 80+% at 5yrs. #RWCS https://t.co/OLjxl4YTLr
09 Feb 2018 Social Kahuna Dr Bevra Hahn, while 5, 10, 20 yr survival in lupus has improved, it's plateaued since 1990. There's still more to do. #RWCS https://t.co/1H7FRFrXmT
07 Feb 2018 News Nailfold Capillaroscopy Portends Prognosis in Systemic Sclerosis
05 Feb 2018 Social Metanalysis of 7 RCTs and 655 SLE patients shows no difference in remission rates & efficacy between low and high dose CTX regimens, but more infections and menstrual problems with high dose CTX https://t.co/bqW6zYLdjP
03 Feb 2018 Social RT @lupuscyclopedia: Know anyone with #lupus who speaks Spanish?: tell them about- "Hablemos de Lupus" https://t.co/8qnjF8UuhJ A... https…
02 Feb 2018 Social RT @DrPetryna: Decreased methylation of type I interferon-regulated genes along with multiple other DMCs observed in SLE. Longitudinal stud…
01 Feb 2018 News Poor Prognosis of the MDA-5 Antibody in Dermatomyositis
31 Jan 2018 News Inefficacy of Immunosuppressive Treatments in Systemic Sclerosis with ILD
30 Jan 2018 News ESRD Death Declines in Vasculitis Patients
29 Jan 2018 Social Of 1342 Scleroderma pts, 83% presented with Raynauds as 1st symptom (17% did not). Survival was different in RP+ vs RP-, 83 vs. 62% at 20 yrs, 71 vs. 50% at 30 yrs. Mortality highest in older, male, dcSSc subset, ILD, PAH, renal crisis, heart involvement. https://t.co/yJhHjz8UPl
29 Jan 2018 Social In 116 PM/DM pts w/ ILD - 14 died w/in 6 months. Risk for early death: upper lung lesions (OR 8) & hypocapnia (OR 6.8). Serious infection. in 1/3. Risk factors include high serum KL-6 (OR 3.7), high dose steroid (OR 4.2), combo immunosuppressives(OR 5.5) https://t.co/px6lucIl2K
28 Jan 2018 Social Despite Rx with different doses of steroids, lg study of PMR (n=12,136) and GCA (n=2673) shows increased rate of fractures (not different between PMR & GCA) of 1.5 fractures per 100 PY. Read at RheumNow https://t.co/VZ1jTmpfTQ