Tuesday, 31 Mar 2020

Autoimmune/Lupus

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30 Jan 2020 Social CDC reports 4 case cluster of Lyme disease at a N. Carolina wilderness camp, 3 in children aged 6–8 yrs. All were positive B. burgdorferi IgM western blot. NC has a low incidence of reported Lyme disease cases
28 Jan 2020 Social Prospectively study of neuropsychiatric (NP) events in1827 SLE - found that NP-SLE occured in 52%; with 31% directly attributed to SLE. Risk of NP-SLE was highest in the first 2 years (RR 6.16) and mortality risk was higher in NP-SLE pts ((16% vs 7%) https://t.co/03wfX5SxNm
27 Jan 2020 Social Administrative claims study from British Columbia showed the risk of type 2 diabetes is significantly lower in SLE pts taking Plaquenil (HCQ). 1,498 SLE pts (91% F) were followed 4.6 yrs with 140 incident T2DM; lower HR (0.61) for those adherent to HCQ https://t.co/OqUQtHz6Hf
20 Jan 2020 News Steroid-Sparing Effect of Tocilizumab in Refractory Takayasu Arteritis
16 Jan 2020 News TULIP2 - Anifrolumab Succeeds in Lupus
13 Jan 2020 News Steroids Up the Risk of Organ Damage in SLE
10 Jan 2020 Social Among 1827 SLE pts, 52.3% had neuropsychiatric (NP) events attributed to SLE. In first 2 years the relative risk for SLE NP events was 6.16. Mortality was higher with NP events attributed to SLE (16%) versus no NPSLE events (6%) https://t.co/uCx5Uf9kJj
10 Jan 2020 News Treatment of Statin-induced anti-HMGCR myopathy
09 Jan 2020 Social Dr. Heidi Jacobi #UTSW lecturing on scleromyxedema often with "pebble like" lesions that during it from scleroderma https://t.co/5odVXrglyT
03 Jan 2020 Social Check out my 2019 Rheumatology Year in Review - now on RheumNow https://t.co/sYb3KvivJK
28 Dec 2019 Social Kaiser Permanente study of 1,956 adult #SLE patients shows that only 58% of lupus pts were ≥80% adherent to hydroxychloroquine. Only age and increasing visits were predictive. Not predictive were the rheumatologist, center or socioeconomic factors. https://t.co/m0oN1OC9bn
27 Dec 2019 Social Antiphospholipid syndrome incidence is 5 per 100k/Yr; lesser known complications include Libman Sachs valve dz, livedo reticularis, racemosa, skin ulcers/necrosis, GN, thrombotic microangiopathy, AVN, non-traumatic fractures https://t.co/rWlWZ39Lhd
27 Dec 2019 Social Check out last weeks RheumNow Podcast - A Merry Lupus XMAS! videocast >> https://t.co/rFJQjVJIOc or the podcast >> https://t.co/blaXn1N5By
24 Dec 2019 News Best of 2019 - 2019 EULAR Guidelines on Antiphospholipid Syndrome Management
24 Dec 2019 News Best of 2019 - New EULAR/ACR Classification Criteria for SLE
19 Dec 2019 News Belimumab in Lupus Nephritis
19 Dec 2019 News Is Anifrolumab Good Enough for Systemic Lupus Erythematosus?
18 Dec 2019 News Fewer Lupus Flares on Low Dose Steroids
12 Dec 2019 News CRP in SSc: Identifying a Severe Phenotype
11 Dec 2019 Social J Rheum metanalysis of 12 studies & 3,234 SLE pt vs 288,336 control subjects shows a significant association between SLE occurrence and current-smoker (not former) (OR 1.54) https://t.co/shL8LT6Kbj