Thursday, 20 Feb 2020

Autoimmune/Lupus

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23 Jul 2015 Social Apremilast useful in lupus? 8pt open label trial in discoid LE showed significant skin improvement @ 85d (by CLASI) http://t.co/v7iCv5H7zq
22 Jun 2018 Social RT @Lupus_SM: Curious to find out how Immunosuppressant use and hospitalisation pattern for #SLE have evolved between 2005 and 2013? Find o…
15 Feb 2020 Social Common immunodeficies. Dr Anna Postolova at #RWCS2020 @RWCSmtg https://t.co/rpjrmcl8t6
04 Nov 2017 Social RT @isa75012: CAPS is a complementopathy. B2GP is homolog to factor H. And there is a treatment!! Eculizumab (anti-C5a) #ACR17
07 Nov 2017 Social RT @DrBhana: Memorize this slide: work up for Asymptotic HyperCKemia #acr17 https://t.co/AmVPB0t0s3
12 Nov 2019 Social RT @Janetbirdope: SLE has high work disability. Interestingly work disability was not high in some organ systems such as renal but mild GN…
05 Dec 2016 Social Catastrophic antiphospholipid registry:500 pts, 30% SLE, death in 37%; renal 73%, lung 60%, half w/ CNS, heart, skin https://t.co/3fWqYlLZ4p
14 Apr 2017 Social Anabasum is a oral endocannabinoid-mimetic binds to CB2 receptor, will enter a phase III trial in Systemic sclerosis https://t.co/2qeDOA32bT
04 Sep 2015 Social Cogan's syndrome:Rare, w/ interstitial keratitis & sensorineural hearing loss +/- syst vasculitis. Rx steroids, INFLX http://t.co/xwqgrGu6fI
06 Apr 2016 Social Morphea can be more than skin deep; MRI and biopsy proven thickening of fascia. https://t.co/4sTMKrSgS0
22 Jul 2018 Social Prevalence of Lupus has increased over 16 yrs; Canadian adminstrative claims data shows lupus 6x more common in women than men. From 2000–2015 incidence 4.43 per 100K population. 2015 prevalence was 90 per 100,000 https://t.co/BV3WhbGISd
22 Oct 2018 Social RT @NicoleBitencou5: In the largest study of #pregnancies in pts with #SLE in the US, a decline in maternal mortality and fetal death from…
15 Feb 2019 Social Analysis of a large Pediatric hospital database and 5679 SLE admissions shows that 12.4% had Pericardial Effusion (PCE) at entry. PCE was assoc w/ 2.5 higherrisk of In-hospital mortality(p 0.027) and 1.5 time more 30Day readmissions (p 0.001). https://t.co/XS6FEGfdH5
17 Apr 2018 Social Lupus care provided by a Lupus specialty vs General Rheumatology (GRC) shows LC w/ better quality measures [86% vs 70%] w/ better APL testing, DXA, steroid sparing , ACE inhibitor use Moderate correlation between the MDs #SLE patients and QM performance https://t.co/HeHZgkA0Gv
16 Sep 2019 Social Despite several Vitamin D intervention RCTs in SLE failing; a metanalysis shows Vit D levels low in SLE, esp if SLEDAI >10. Deficiency of Vit D incr SLE risk (OR=4.37) and Vit D levels were inversely correlated with SLEDAI (correlation coefficien = −0.50) https://t.co/M39lzISw09
05 Nov 2017 Social RT @DrRachelTate: Pre-clinical assoc between serologic measures of EBV reactivation and SLE disease transition. #ACR17 @RheumNow #910 https…
10 Nov 2017 Social RT @ACRheum: EULAR & ACR present draft of new #SLE Classification Criteria at the 2017 ACR/ARHP Annual Meeting.→ https://t.co/PaviXkg9BT #A…
03 Dec 2019 Social Study of two dietary patterns and the risk of SLE from the Nurses' Health Study (NHS, 1984–2014) and Nurses' Health Study II (NHSII, 1991–2015) shows no association between incident lupus and (healthier) prudent or (less healthy) Western diet. https://t.co/tvX2HqzWxF
04 May 2016 Social May is lupus awareness month. https://t.co/Ri6ZOQ7Ae9
05 May 2015 Social Study of 513 GPA (Wegeners) patients; 3.3% had cardiac involvement - unrelated to ANCA positivity or disease activity http://buff.ly/1R7HwIp