Wednesday, 20 Nov 2019

Autoimmune/Lupus

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26 Aug 2019 Social Full read review of "Management of Refractory Lupus Nephritis" https://t.co/Cu4QckxRIo
14 Aug 2019 News With Autoimmunity, Checkpoint Inhibitors Can Be Used
10 Aug 2019 Social The RheumNow Podcast is up! "Tricked Up Lupus Criteria" and more on gout & ULT, IVIG in ANCA vasculitis, NO SIE risk w/ TNFi, and the Best 1st Biologic. Watch the video here>> https://t.co/j1Axn36hL0 or listen to the Podcast on iTUNEs or SoundCloud here>> https://t.co/rjAQmxHce6
09 Aug 2019 Social IL-16 studied in Scleroderma: incr perivasc IL-16 lymphocyte expression w/ more IL-16+ cells in dcSSc vs lcSSc (44 vs 29%, P<0.05). Serum IL-16 levels elevated in SSc pts (297 vs 195 pg/ml) & IL-16 correlated w/ dcSSc, skin score, erythema & pigmentation. https://t.co/lC4nRO6AH0
07 Aug 2019 News New EULAR/ACR Classification Criteria for SLE
02 Aug 2019 News Sjogren's Syndrome at Risk for Psychiatric Disorders
01 Aug 2019 Social Candian study of 376 pregnancies (284 F) with #SLE and drug use: only 24.2% on antimalarials, 8.2% azathioprine, 19.7% steroids & 4.8% on NSAIDs during pregnancy. 1st trimester discontinuations seen in 16.7% of HCQ & 29.2% AZA https://t.co/YoRUXU9RJB
30 Jul 2019 Social Cohort study shows ACE inhib. in Systemic Sclerosis at Dx was assoc w/ increased risk for Scleroderma Renal Crisis (SRC). Military System EHR study of 31 SRC to 332 non-SRC & found ACEi assoc w/ SRC (OR 4.1; CI 1.6–10.2) only in presence of proteinuria https://t.co/cMsheXrmRY
29 Jul 2019 News Abatacept Disappoints in Systemic Sclerosis
25 Jul 2019 News FDA AAC Splits Vote in Favor of Nintedanib for Scleroderma Interstitial Lung Disease
22 Jul 2019 Social Study from National Inpatient Sample (2002-11) , 424 hospitals, 4024 #SLE pts admitted w/ sepsis. Mortality varied from 0-60%. Hospitals that treated ⩾3.9 patients with SLE and sepsis annually had a lower risk of lupus mortality (10% vs 17%; P = 0.004). https://t.co/TuVfaGUpcM
22 Jul 2019 News FDA Approves Apremilast for Behcet's Oral Ulcers
19 Jul 2019 Social There was no increaesd risk of cancer in 767 patients with giant cell arteritis in western Norway was compared to matched controls https://t.co/25gf89Ty0f
17 Jul 2019 Social 10 question UK survey on the use of HCQ in 989 patients (71% SLE; 12% UCTD/MCTD, 5.2% skin lupus, 11.5% RA, SS, etc). Results: 56% never had HCQ side effects; 23% had AE that improved; 12% had AE currently & 8.6% stopped HCQ for AE. https://t.co/iqJl0eEPTg
16 Jul 2019 News Cardiovascular Disease Increased in Hospitalized Lupus Patients
11 Jul 2019 Social Increased time spent in lupus low dz activity state (LLDAS) reduces healthcare costs. Among 212 SLE pts analyzed; increased cost assoc w/ damage & steroid use, but spending ≥50% of time in LLDAS resulted in a 26% reduction in direct medical cost https://t.co/Kfd064kZFX
10 Jul 2019 Social Study of 28 states and 10.268 lupus Medicaid patients showed that only 15% were adherent to Plaquenil treatment. Adherence was lower in blacks living in certain zip codes but not in zip codes prevalents for Hispanic, white, education, poverty level. https://t.co/ytFXaOGKB2
09 Jul 2019 Social RTX product label lists Serum Sickness (SS) as uncommon postmarketing AE. Study of 37 pts w/ RTX SS finds that 3/4 occurred in SLE & autoimmune dz; 1st inf54% during 1st injxn, usually w/in 12 days. Manifest as MSK sx (92%), fever (87%), skin lesions(78%) https://t.co/gc8CUXhqxL
09 Jul 2019 News Pregnancy Outcomes Improve in Lupus
08 Jul 2019 Social Metanalysis shows the prevalence of autoimmune hepatitis for Asian, European, and American populations was 12.99 (95% CI: 2.05–23.92), 19.44 (15.63–23.24), and 22.80 (13.48 to 59.07) per 100,000; higher rates seen in women and elderly https://t.co/OtvvWBvb3x