Friday, 15 Nov 2019

Autoimmune/Lupus

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28 Mar 2018 Social Ablynx announced that its drug vobarilizumab (anti-IL-6R nanobody) failed to meet its primary endpoint of dose response in a phase II SLE trial. https://t.co/9Zaw10FFJS
26 Oct 2018 Social RT @Rheumforall: Remember cutaneous lupus can be caused by medication. This changes our treatment. https://t.co/UQZE65aOFk
17 Sep 2017 Social RheumNow Wk in Review on SLE + metabolic syndr, bisphosphonate holidays, 2 biologies of vasculitis, wonders of Vit D https://t.co/Eop4eziGfw
29 Apr 2017 Social RT @DrRachelTate: Pearls on Scleromxyedema and scleredema from Dr. Hummers @RheumNow #SOTA2017 https://t.co/z7ZjJgtWhD
12 May 2016 Social Retrospective study from Brigham shows adverse SLE pregnancy outcomes assoc. w/ nephritis, cytopenia, serositis https://t.co/SYYTZQEbC2
06 Nov 2017 Social RT @psufka: Great work! Shrinking lung syndrome in lupus is condition we should all be aware of to have on our differential. #ACR17 @rheumn…
08 Aug 2018 Social Using HCQ levels and Pt Surveys to define adherence, Intl study of 305 SLE pts shows 18.4% of patients as severely nonadherent & 23.4% of patients as nonadherent. There was moderate agreement between questionnaires, drug level, and physician assessment https://t.co/X1HSQc1S8b
03 Jul 2015 Social NEJM reviews Jaccouds arthritis in lupus - reducible finger deformities, despite being seronegative for RF/CCP http://t.co/MZJyjnofIG
04 Feb 2016 Social Majority of pediatric lupus w/ acute pancreatitis develop macrophage activation syndr w/ high mortality rate https://t.co/CmT3Gsb4a7
13 Sep 2015 Social RT @SjogrensCa: Immune Components of Liver Damage Associated with Connective Tissue Diseases http://t.co/z5XlKc6TCA #sjogrens #rheum
15 Dec 2018 Social Bing Bingham MD talking on immune related adverse events (MSK and autoimmune). Says these occur in 3-5% of cancer pts treated with Checkpoint inhibitors. Unofficial surveys show nearly 50% of Rheums have seen these referrals. #MARS #ARTHROS https://t.co/yZHMQjpMz8
19 Oct 2017 Social Nearly half Catastrophic APS triggered by infections. Much less are surgery, SLE, stopping anticoagulants.… https://t.co/altMOsLOez
30 Apr 2017 Social RT @DrRachelTate: Current secondary thrombosis prevention targets for INR. Dr. Erkan @RheumNow #SOTA2017 https://t.co/zGKLxMLa3Q
13 Jun 2016 Social NEJM vignette showing Gastrointestinal complications of GPA; bowel vasculitis, hemorrhage, hemoperitoneum https://t.co/I13vFVPeAL
29 Aug 2019 Social Among 312 Lupus patients, epilepsy seen in 36 (11.5%)- 30 had focal onset. Half had NPSLE. NPSLE + Epilepsy were more likely to have APS; and Cerebrovascular dz & psychosis were 2-3 fold higher (compare to NPSLE without epilepsy (p<0.001). https://t.co/jOb4WkbxL4
06 Feb 2019 Social Kaiser Permanente study of 1,956 adult #SLE patients shows that only 58% of lupus pts were ≥80% adherent to hydroxychloroquine. Only age and increasing visits were predictive. Not predictive were the rheumatologist, center or socioeconomic factors. https://t.co/2mpkaBK4YZ
05 Aug 2015 Social Data from Nurses Health Study shows endometriosis poses modest risk for Lupus (HR 2.0) and RA (1.4) http://t.co/VMo5exEQZF
29 Feb 2016 Social Post. reversible encephalopathy (PRES) is rare in #SLE. ^Risk w/ HTN, CRI, Dz activity, lymphopenia, ^Lipids, youth https://t.co/QHFQREnIxA
29 Sep 2015 Social SSA+ in Preg have more AV block, but not more SLE or Sjogrens. But SLE & SS pts had more Cesareans, Pre-term & IUGR http://t.co/6mSAbdp4gm
04 Nov 2017 Social RT @DrBhana: Lupus retinopathy #ACR17 https://t.co/qkuecgMHCk