Friday, 13 Dec 2019


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06 Apr 2017 Social Dr Torgerson Complement deficiency in SLE: C2 40% homozytotes get lupus GN; C4 - 75% get GN; C1q/r/s def 90% get SLE or GN, usually young
14 May 2017 Social EUSTAR Study: Scleroderma pts w/ RNA polymerase III Abs have higher risk of cancer (OR 7.38), esp w/ age & more skin
20 Oct 2017 Social Dr Munther Khamashta #APLAR2017 on Catastrophic APS seen in 0.8% of APS pts.
08 Jan 2018 Social Interesting collection of pictures of localized scleroderma.
06 May 2019 Social Cohort study finds 6/420 (1.4%) of SLE patients had steroid induced pancreatitis is - half of them died. Lit review finds 451 lupus pancreatitis with majority developing pancreatitis w/in 3 days of medium-to-high dose steroids (mortality = 37.5%).
07 Oct 2019 Social T2T in Lupus Nephritis aims for less proteinuria, Study of 87 pts with class III/IV LN compared goal of urine protein/creat ratio(UPCR) < 0.5 to stringent < 0.15, Latter assoc w/ lower renal flares (HR  0.16), less CKD (HR 0.19), more MMF use (HR = 7.26)
17 Sep 2015 Social DrPetryna A study reveals Female patients with #Polymyositis may suffer from subclinical ovarian dysfunction.
27 Sep 2016 Social EGPA (Churg-Strauss)157pts:12y delay in Dx, severe asthma predates systemic Sx 12 yrs, asthma worse 3-6mo before Dx
30 Nov 2016 Social UK study shows risk of Giant Cell Arteritis increased with increasing Prior infections, less so Herpes zoster.
12 Apr 2017 Social RheumNow 5Q survey on if PATIENTS will use BIOSIMILARS. Please vote if youre a patient w/ #RA, #PsA, #PSO, #AS, #IBD
15 May 2017 Social MDA-5 Ab+ assoc w/ clinically amyopathic DM, ILD, rapid-progrsv ILD, lower CK/Aldolase/ANA+ or cytoplasmic pattern
31 Oct 2017 Social 18FFDG-PET superior to clinical scoring in Dx of PMR (pre-pred) w/ sensitivity 85%, specificity 87%, PPV 93% NPV 74%
07 Nov 2017 Social RT @doctorakerkar: Blunted coronary flow reserve in # Lupus & RA #ACR17 @RheumNow
21 Jan 2018 Social RT @Lupusdoc: Steroid use in SLE: highly variable dosing across centres and no downward trend in use over the past…
16 Jan 2019 Social Who thought this was possible? Numbers suggest this is rare. Tis wrong to use this to forge ahead with an unlikely PMR dx in the face of a normal CRP/ESR; but will you go so far as to order the expensive FDG-PET?
26 Jul 2016 Social CHMP has recommended abatacept for 1st line use (before MTX) in moderate to severe RA. EMA to consider approval
17 Mar 2016 Social Some Interstitial nephritis pts have autoantibodies against a water-channel protein in collecting tubules.
22 Oct 2015 Social Treating Pericarditis: (Dx 1st!) NSAIDS, colchicine, Steroids (low then higher doses); anakinra for recurrent Dz
24 Oct 2016 Social RT @NatRevNeph: In our November issue: Scleroderma renal crisis and renal involvement in systemic #sclerosis https:…
18 Jan 2017 Social 240 GCA pts; CVA occurs 73% at dx, CVA pts had more ophthalmic sxs, lower ESR/CRP/Hgb & involved Vertebrobasilar A.