Tuesday, 16 Jul 2019

Autoimmune/Lupus

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23 May 2019 Social Should all CTD patients have PFTs? Review suggests all should have PFTs, DLCO, HiRes Chest CT given prevalence of ILD in RA, PSS, SLE, myositis. PFTs have prognostic value in RA-ILD, esp w/ UIP, but other CTDs have less data on sensitivity/specificity https://t.co/fmG9HfHLt3
23 May 2019 Social multicenter, cross-sectional study of 1526 adult Behcets patients from Egyptian rheumatology centers shows CNS, DVT, and GI tract involvement is higher in males, while the joint dz and disease activity were increased in females. https://t.co/oDDRXmBfw3
22 May 2019 News Lupus Outcomes Influenced by Race/Ethnicity
22 May 2019 Social Toronto Lupus clinic follow up of 267 patients followe for > 10 years finds that only (10% achieved prolonged clinical remission and 18% attained prolonged Low Dz Activity. Both groups had similar low flare rates - 0.038 & 0.065 flares/year/pt. https://t.co/iLJKW0Q7FQ
16 May 2019 News Risk Score Predicts Thrombosis Recurrence in APS
14 May 2019 Social Adverse childhood experiences (ACEs) were studied in 269 SLE registry (CLUES) pts and compared to California BRFSS controls. 63% had 1+ ACE & 19% had 4+ ACEs. Higher ACE levels assoc w/ worse patient-reported SLE activity, depression, and health status https://t.co/OtvecXh9ow
14 May 2019 News Racial Disparities in Mortality Associated with Systemic Lupus Erythematosus
09 May 2019 News Calcineurin Inhibitors in Anti-Synthetase Dermatomyositis ILD
08 May 2019 News Biomarkers Predict Thrombosis in Lupus
07 May 2019 News Monocyte Patrolling Contributes to Lupus Glomerulonephritis
06 May 2019 Social Cohort study finds 6/420 (1.4%) of SLE patients had steroid induced pancreatitis is - half of them died. Lit review finds 451 lupus pancreatitis with majority developing pancreatitis w/in 3 days of medium-to-high dose steroids (mortality = 37.5%). https://t.co/QsIHsl44qx
01 May 2019 Social Study of 14928 Autoimmune/Rheum Dz pts in UK Clinical Practice Research database found the influenza vaccination was not associated with arthritis flare or increase in PCP visits (actually lowered consultas for joint pain in following 90 days) https://t.co/rrwu68g7DM
30 Apr 2019 Social Rheumatic disorder with hepatic origins/involvement include primary biliary cholangitis, autoimmune hepatitis, primary sclerosing cholangitis, SLE/overlap, AOSD, Hemophagocytic syndrome. https://t.co/N61uq1AioZ
30 Apr 2019 News High GPA Hospital Readmission Rates
30 Apr 2019 Social Full Read review of CLE - cutaneous lupus from Werth and colleagues at UPenn. Focused on new therapies and clinical trial issues. https://t.co/NCB0IF7tWO
30 Apr 2019 Social Pectus carinatum or "Pigeon Chest" is a chest wall deformity w/ costal cartilage overgrowth pushing forward the manubrium/sterum; predominantly males (4:1F) also @ risk for scoliosis, Marfans, valvular/aortic disease, psychologic problems https://t.co/tL7vDfZDVT
29 Apr 2019 Social Benlysta is approved for use in pediatric SLE based on the 80 pt PLUTO trial; 1 yr of PBO vs 10 mg/kg belimumab plus standard therapy. Results presented at ACR2018 shows BEL in pediatric SLE to be safe and effective (SRI4 resp 52.8% vs 43.6%). https://t.co/cjqPaWu92O.
26 Apr 2019 ACR Video RheumNow Live Preview with Dr. Ken Kalunian (New Criteria, Guidelines & Outcomes in Lupus)
23 Apr 2019 ACR Video RheumNow Live Preview with Dr. Paul Monach
23 Apr 2019 News Improved Survival in Lupus