Wednesday, 18 Jul 2018

Autoimmune/Lupus

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24 Apr 2018 Social 125 SLE pts were hospitalized w/ 187 serious infxn. Pulmonary (37.9%), sepsis (22.5%) & Gram-negatives (38.2%) predominated. Predictors of Infx-related mortality- SLE flare (HR 3.98) & bacteremia (HR 2.54); HCQ was protective of infx mortality (HR 9.26). https://t.co/XHGRVGWTJt
24 Apr 2018 Social Study of 537 GCA pts undergoing temporal artery bx shows the value of CBC elements in predicting a +Bx: Thrombocytosis (OR 4.44), NLR (OR 1.81), PLR (OR 3.25), CRP (OR 3.00), ESR (OR 3.62), increased age (OR 1.03) https://t.co/3XvzBR5cEh
21 Apr 2018 Social RT @RheumNow: The RheumNow Wk in Review is up. Discussions on Vitamin D, Rheumatologist salaries, Lupus clinics, VTE, FDA hearings Listen…
20 Apr 2018 News Wear Your Pajamas to Work for Lupus
17 Apr 2018 Social Lupus care provided by a Lupus specialty vs General Rheumatology (GRC) shows LC w/ better quality measures [86% vs 70%] w/ better APL testing, DXA, steroid sparing , ACE inhibitor use Moderate correlation between the MDs #SLE patients and QM performance https://t.co/HeHZgkA0Gv
15 Apr 2018 Social RT @BolekBerqui: Love listening to Michelle Petri talking about anemia in SLE. #SOTA2018 https://t.co/m7EEdV5FsE
12 Apr 2018 Social Study of 150 SLE pts shows that fracture risk is increased with age, body mass index, fat mass, smoking, and rheumatoid arthritis. https://t.co/9b3ewmrVtc
12 Apr 2018 News SynBioSe: Combo Rituximab and Belimumab Succeeds in Severe Refractory Lupus
11 Apr 2018 News Increased Comorbidity Burden in Lupus African Americans
08 Apr 2018 Social Of 154 patients with a negative Temp artery Bx 20% were eventually diagnosed with GCA. Predictors of GCA in TAB neg pts were meeting ACR criteria (OR 13.4), clinical dx of PMR (2.8), high platelet counts (1.3). https://t.co/dpsSgqQWn9
03 Apr 2018 Social Of 154 patients with a negative Temp artery Bx 20% were eventually diagnosed with GCA. Predictors of GCA in TAB neg pts were meeting ACR criteria (OR 13.4), clinical dx of PMR (2.8), high platelet counts (1.3). https://t.co/dpsSgqQWn9
31 Mar 2018 Social RT @lupuscyclopedia: Check out my book - 'The Lupus Encyclopedia: A Comprehensive Guide for Patients and Families (A ...' - on #BookBuzz -…
31 Mar 2018 Social RT @Lupus_SM: Women with #SLE have an increased risk of preeclampsia, preterm delivery and small for gestational age babies. #pregnancy #lu…
28 Mar 2018 Social Ablynx announced that its drug vobarilizumab (anti-IL-6R nanobody) failed to meet its primary endpoint of dose response in a phase II SLE trial. https://t.co/9Zaw10FFJS
28 Mar 2018 Social Analysis of US hospitalizations from 7 states compared 28269 lupus w/ 13269 controls; SLE associated with 33% more postoperative renal complications % 27% greater in-hospital mortality, BUT no higher rate of cardiac complications https://t.co/e40HUEWzmY
27 Mar 2018 Social FDA grants Fast Track designation to nintedanib for Rx of systemic sclerosis with interstitial lung disease, for which there is no approved therapy. Pending are results from SENSCIS study -nintedanib over 52 weeks in SSc-ILD. https://t.co/CdnhvETtCZ
26 Mar 2018 Slide of the day Comparison of Rhupus and RA
26 Mar 2018 News The Consequences and Cure of Hepatitis C
23 Mar 2018 Social Norweigian registry shows lupus women are twice as likely as RA to become pregnant and significantly shorter time to become pregnant (3.0 vs 7.0 mos). Low RA #s are due to age, medications, physical limitations. https://t.co/nc6nnPJ7zr
22 Mar 2018 News mTOR Inhibition with Sirolimus Effective in Lupus