Monday, 28 May 2018

Autoimmune/Lupus

Datesort ascending Type Title Save
01 Feb 2018 News Poor Prognosis of the MDA-5 Antibody in Dermatomyositis
31 Jan 2018 News Inefficacy of Immunosuppressive Treatments in Systemic Sclerosis with ILD
30 Jan 2018 News ESRD Death Declines in Vasculitis Patients
29 Jan 2018 Social Of 1342 Scleroderma pts, 83% presented with Raynauds as 1st symptom (17% did not). Survival was different in RP+ vs RP-, 83 vs. 62% at 20 yrs, 71 vs. 50% at 30 yrs. Mortality highest in older, male, dcSSc subset, ILD, PAH, renal crisis, heart involvement. https://t.co/yJhHjz8UPl
29 Jan 2018 Social In 116 PM/DM pts w/ ILD - 14 died w/in 6 months. Risk for early death: upper lung lesions (OR 8) & hypocapnia (OR 6.8). Serious infection. in 1/3. Risk factors include high serum KL-6 (OR 3.7), high dose steroid (OR 4.2), combo immunosuppressives(OR 5.5) https://t.co/px6lucIl2K
28 Jan 2018 Social Despite Rx with different doses of steroids, lg study of PMR (n=12,136) and GCA (n=2673) shows increased rate of fractures (not different between PMR & GCA) of 1.5 fractures per 100 PY. Read at RheumNow https://t.co/VZ1jTmpfTQ
26 Jan 2018 Social Drug induced lupus may be caused by hydralazine, procainamide, isoniazid, minocycline, diltiazem, TNF inhibitors. Drug induced SCLE may be from HCTZ, terbinafine, PPI, TNFi. https://t.co/d8F4PUzASO
25 Jan 2018 Social 0.01% of all Emergency Dept Visits are for Septic Arthritis. Stable rates between 2009-12, ~83% are hospitalized, moreso in those with comorbidities. https://t.co/7xEg9FX5GB.
23 Jan 2018 Social Among 286 SLE from the NHS, 42% were dsDNA+ at diagnosis. Current smokers were more likely to be dsDNA+ (HR 1.86) & >10 Pk-yr hx had elevated dsDNA+ SLE risk (HR 1.60) https://t.co/0RSI7r3zWP
22 Jan 2018 Social Offspring to Lupus mothers have lower birth weights. Active SLE assoc w/ 5 fold higher risk preeclampsia, and 8 fold risk of Preterm birth https://t.co/1c2z6mAhJX
21 Jan 2018 Social RT @Lupusdoc: https://t.co/ElqvrKfXDy Steroid use in SLE: highly variable dosing across centres and no downward trend in use over the past…
17 Jan 2018 Social Checkpoint inhibitor use in autoimmune and inflammatory disease (AID) pts is associated with higher rates of immune-related AE 44.4%) with half these being a flare of underlying AID. https://t.co/aNHIE86B8r
15 Jan 2018 News Stroke Risk Confirmed in SLE
09 Jan 2018 Social Checkout Dr. Greg Silvermans #ACR17 Video on the links between microbiome alterations, Lupus and Nephritis - A plenary session standout! https://t.co/6TR92pWotb
08 Jan 2018 Social Checkout Dr. Philip Robinsons #ACR17 video from the ACR Session on Vascular and Pulmonary Complications of Scleroderma https://t.co/fmHV1pROmQ
08 Jan 2018 Social RT @DrPetryna: Pivotal Ph3 52 wk NE Asia multi-center trial of belimumab in SLE pts reveals significantly improved SRI (53.8% Bel vs 40.1%…
08 Jan 2018 Social Interesting collection of pictures of localized scleroderma. https://t.co/rQgzOxJcLE
06 Jan 2018 Social From a Colombian Chikungunya Virus cohort; 33/103 pts were seropositive CHIKV and had chronic arthritis for 22 mos, mean TJC 5, SJC3. https://t.co/0DTTpAgRl6
05 Jan 2018 News Stem Cell Transplant Succeeds in Scleroderma
04 Jan 2018 Social RT @DrAiLynTan: In #scleroderma, myeloablative autologous stem-cell transplantation superior to monthly cyclophosphamide Long-term benefit…