Thursday, 20 Feb 2020


Datesort ascending Type Title Save
18 Sep 2019 News FDA Grants Breakthrough Status for Potential Lupus Nephritis Drug
17 Sep 2019 Social Despite RCTs showing RTX doesnt work in SLE - rheums still use it. Review of 147 SLE pts on RTX shows better outcomes in those w/ a low # prior DMARDs & low C4 levels. Lesser resp w/ Joint dz. (>1/2 had prior MMF, AZA, HCQ; 1/3 CTX or MTX)
16 Sep 2019 Social Despite several Vitamin D intervention RCTs in SLE failing; a metanalysis shows Vit D levels low in SLE, esp if SLEDAI >10. Deficiency of Vit D incr SLE risk (OR=4.37) and Vit D levels were inversely correlated with SLEDAI (correlation coefficien = −0.50)
15 Sep 2019 Social RT @sclerodermaUM: I found this to be extremely helpful for recommending cannabinoids.
11 Sep 2019 Social A changing spectrum of Hydralazine induced lupus? Several reports showing cases of the usual (pleuropericarditis, arthriti + Skin, +ANA) but also the unusual (ANA neg, ANCA/PR3/MPO positive, Bx proven nephritis and +ACL, +dsDNA)
10 Sep 2019 News Riociguat Fails in Systemic Sclerosis-Associated Digital Ulcers
09 Sep 2019 News Nintedanib FDA Approved for Scleroderma Lung Disease
09 Sep 2019 Social FDA Approves Ofev (nintedanib) for Interstitial Lung Disease Associated with Systemic Sclerosis or Scleroderma (SSc-ILD) PI:
03 Sep 2019 Social Drug use by #SLE patients during 376 pregnancies (284 women) was studied. HCQ was used in 24.2%, but was discontinued 17% in the year prior, 30% in 1st trimester, 10% in 2nd trimester & 26% in 3rd trimester. Education on utility of HCQ during Pred needed!
03 Sep 2019 Social Taiwanese matched cohort study shows that #SLE patients with acute MI have higher mortality rate and prolonged hospitalization after AMI. Aggressive control may decrease risk of AMI for SLE patients.
30 Aug 2019 Social Anifrolumab (anti-IFNa) was shown to be effective in its 2nd phase III trial in SLE - meeting its primary (BiCLA) endpoint at week 52, according to an Astra-Zeneca press release. Full data to be presented at an upcoming medical meeting.
29 Aug 2019 Social Among 312 Lupus patients, epilepsy seen in 36 (11.5%)- 30 had focal onset. Half had NPSLE. NPSLE + Epilepsy were more likely to have APS; and Cerebrovascular dz & psychosis were 2-3 fold higher (compare to NPSLE without epilepsy (p<0.001).
29 Aug 2019 Social RT @karen_kc123: I recently spoke with Rheumatology Advisor, where we discussed an important issue -the barriers in SLE diagnosis, care, an…
26 Aug 2019 Social Full read review of "Management of Refractory Lupus Nephritis"
14 Aug 2019 News With Autoimmunity, Checkpoint Inhibitors Can Be Used
10 Aug 2019 Social The RheumNow Podcast is up! "Tricked Up Lupus Criteria" and more on gout & ULT, IVIG in ANCA vasculitis, NO SIE risk w/ TNFi, and the Best 1st Biologic. Watch the video here>> or listen to the Podcast on iTUNEs or SoundCloud here>>
09 Aug 2019 Social IL-16 studied in Scleroderma: incr perivasc IL-16 lymphocyte expression w/ more IL-16+ cells in dcSSc vs lcSSc (44 vs 29%, P<0.05). Serum IL-16 levels elevated in SSc pts (297 vs 195 pg/ml) & IL-16 correlated w/ dcSSc, skin score, erythema & pigmentation.
07 Aug 2019 News New EULAR/ACR Classification Criteria for SLE
02 Aug 2019 News Sjogren's Syndrome at Risk for Psychiatric Disorders
01 Aug 2019 Social Candian study of 376 pregnancies (284 F) with #SLE and drug use: only 24.2% on antimalarials, 8.2% azathioprine, 19.7% steroids & 4.8% on NSAIDs during pregnancy. 1st trimester discontinuations seen in 16.7% of HCQ & 29.2% AZA