Wednesday, 18 Oct 2017

Biologic/Novel Rx

Date Typesort ascending Title Save
16 Jan 2017 Social Baricitinib decision by the FDA extended from Jan 2017 by another 3 mos for FDA to review major amendment to NDA https://t.co/tMi3llwWZw
17 Jun 2015 Social Metanalysis of 7 RCTs compares high vs low dose RTX in RA shows little clinical difference. Better Xray w/ high dose http://t.co/ySSo3gVKE8
16 Nov 2016 Social RT @rachelthuston: TCZ for clinical remission in GCA but doesn't fully suppress MR signals of vessel inflammation #ACR16 @RheumNow https://…
06 Aug 2017 Social RheumNow Wk in Review is up! FDA hearings on sirukumab, tofacitinib. iTUNES, podcast https://t.co/rX1zLRHUuA & video https://t.co/slvfTJYR1E
15 Apr 2016 Social Tocilizumab to remain a second line treatment for polymyalgia rheumatica. More RCT needed https://t.co/yPcFI9s3CR @DrPetryna
15 Feb 2017 Social Correction: Abbvies JAK inhibitor ABT-494) has a name, Uptacitinib, is currently in phIII trials. #RWCS 2017 info from Dr. M Genovese
07 Sep 2017 Social In 10yrs MTX/biologic use increased (40%/1.7% to 64%/27%) & rate of ortho surgery dropped (72 to 51/1000 pts in 2014 https://t.co/IE72n2YMPB
08 Jun 2016 Social Is there enough data to support a non-TNFi biologic as the 1st choice? Dr. Janet Pope says the data clearly says so https://t.co/Ai5izsTDN8
13 Mar 2017 Social Review of severe alopecia areata 90pts Rx w/ Xeljanz: 20% nearly total regrowth, 58% >50% regrowth,77% some regrowth https://t.co/8BZwOqevct
22 Sep 2015 Social OCTAVE studies shows tofacitinib 10 mg bid to be effective in treating moderate to severe ulcerative colitis http://t.co/MbdSUymAji
23 Oct 2015 Social Pretreatment CRP or IL-6 levels are not predictive of responses to tocilizumab https://t.co/IOQGWOGGQA
14 Apr 2017 Social How will new BIOSIMILAR biologic drugs affect PATIENTS - Make Your views count in a Patient survey; vote at>> https://t.co/ZhM9MiDCd7
27 Nov 2015 Social RCT shows Hidradenitis suppurativa pts respond well to anakinra (esp after wk 8) w/ less IFN and increased IL-22 https://t.co/OfndT569gt
10 May 2017 Social Responses to Orencia may be dependent on baseline memory B cells (CD38+ CD27+) https://t.co/zro040Y54W
23 May 2017 Social FDA approves Actemra as1st approved drug to treat Giant Cell Arteritis. See RheumNow report. https://t.co/73UieZpbn1 https://t.co/HjUzi0H6OL
25 Feb 2016 Social How to manage patients who worry, wont do & negatively inclined re:health/meds - the negative narrator in your head https://t.co/KEeVcWVedr
20 Jul 2017 Social 7 pts w/ Active Refractory Takayasu arteritis Tx w/ RTX w/ mixed results - 3 achieved remission but 4 failed to resp https://t.co/rXSNc6qpTn
20 Mar 2016 Social Tofacitinib meets primary endpoints in ulcerative colitis trials, achieving 16-18% remission rates https://t.co/mkWZTfz213
31 Jan 2017 Social @jhoronjeff @pfizer @US_FDA You missed the point - this is the kind of study that must be done to get an interchangeability indication
29 Nov 2016 Social Good, basic overview of Biosimilars. https://t.co/N0hE8xL8Ga