Wednesday, 18 Oct 2017

Biologic/Novel Rx

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24 May 2017 News Anti-IL-5 Success in Eosinophilic Granulomatosis with Polyangiitis
23 May 2017 Social Kevzara-the 2nd IL-6 inhibitor approved for use in RA; priced at $39K, 30% below competition
23 May 2017 Social FDA approves Actemra as1st approved drug to treat Giant Cell Arteritis. See RheumNow report.
23 May 2017 News Actemra - First FDA Approved Drug for Giant Cell Arteritis
22 May 2017 Social @naseema22537544 @DrSimply The new updated PI says its to be given with a tapering course of steroids.
18 May 2017 Social RT @DrPetryna: @RheumNow could ustekinumab potentially be used in treatment of refractory GCA? Evidence suggests it might…
15 May 2017 Social In #Crohns disease Tofacitinib fails to maintain remission in randomized W/D, results of 2 Placebo RCT.
12 May 2017 Social Uptacitinib (Abbvie Jak 1 inhibitor) shows efficacy in Crohns dz (CELESTE RCTl) w/ remission rates at 6 &24 mg bid
10 May 2017 Social Responses to Orencia may be dependent on baseline memory B cells (CD38+ CD27+)
07 May 2017 Social FDA has accepted Sanofi/Regenerons resubmitted BLA for Sarilumab (IL-6 inhib) for RA w/ PFUFA action date 5/22/17
05 May 2017 Social Japan Study shows 8mg IV Actemra can be escalated to q3 wks IV or reduced to q5 wks IV according to q4wk response
04 May 2017 News Tofacitinib Effective in Ulcerative Colitis
04 May 2017 Social Pfizer submitted tofacitinib NDA to FDA for psoriatic arthritis. FDA prev denied the NDA for psoriasis w/ CR letter.
04 May 2017 Social Fostamatinib (Tavalisse) Syk inhib failed in RA, has been studied in ITP, new NDA for ITP submitted to FDA by Rigel.
01 May 2017 Social OPT 1&2 RCT show Tofacitinib to improve nail psoriasis: NAPSI75 scores PBO 6.8%, Tofa 5mg 16.9%, 10 mg 28.1% bid
29 Apr 2017 Social RT @NYTHealth: You asked: What is it about so many medications that causes dryness in the mouth? Here's a short explanation.…
26 Apr 2017 Social Sandoz biosimilars of Enbrel and Rituxan were recommened by CHMP for approval/use in the EU. EMA decision awaited
21 Apr 2017 Social Small study of 13 alopecia pts (2 totalis, 7universalis); Xeljanz Rx 7/13 had >50% regrowth w/in 9 mos, 2 d/c
18 Apr 2017 Social How will new BIOSIMILAR biologic drugs affect PATIENTS - Make Your views count in a survey; Patients vote HERE>>
17 Apr 2017 News Anti-IL-23 Therapy Effective in Crohn's Disease