Wednesday, 28 Jun 2017

Biologic/Novel Rx

Datesort ascending Type Title Save
07 Sep 2016 Social EU grants approval for Orencia (abatacept; IV or SC) for MTX naive (early) RA patients with moderate-severe disease https://t.co/gcGbESdxCp
07 Sep 2016 Social Power doppler synovitis correlates better w/ S100 Calprotectin levels(more than ESR CRP) & w/ low TNFi trough levels https://t.co/gemAqdEUTJ
06 Sep 2016 Social 30% of Biologics us is monotherapy. Choy etal reviews comparative success, reasons, pitfalls of biologic monotherapy https://t.co/UAtLKQbxx7
30 Aug 2016 Social Dr Carol Langford Gr Rounds - ANCA levels do NOT correlate well with disease activity and should not be used to guide therapy
25 Aug 2016 Social Ixekizumab (Taltz), IL-17 inhibitor, better than Placebo, but same as Humira @24wks in treating psoriatic arthritis https://t.co/mVZ0sMSHdX
23 Aug 2016 Social Idiopathic Recurrent Pericarditis follows ~20% acute pericarditis; responds VERY well to IL-1 inhibition (anakinra) https://t.co/T28ggiTGyA
10 Aug 2016 Social Abbvies IL-6 drug vobarilizumab (+MTX) failed to meet ACR20 primary endpoint against MTX alone (devloped w/ Ablynx) https://t.co/rAV60pQIcu
09 Aug 2016 Social In Japan, persistence on biologics highest in biologic-naïve (>95%) and older Pts & lowest w/ more comorbidities. https://t.co/4VTDOCpZeJ
05 Aug 2016 Social CVS pharmacy drops brand name drugs and prefers biosimilar agents for diabetes and cancer care. https://t.co/IwGCMen2KE
05 Aug 2016 Social RT @HealioRheum: Evolution of biologic structure and nomenclature for MAb: mouse -omab; chimera -ximab; humanized -zumab; human -umab; fusi…
02 Aug 2016 News Biosimilars are Bioequivalent to Original TNF Inhibitors
01 Aug 2016 News Canakinumab Yields Genetic and Disease Modifying Effects in TRAPS Patients
22 Jul 2016 Social In Tofacitinib RCTs 1821 child-bearing age F exposed; 47 pregnant (33 monoRx). 1 Pulm valve stenosis, 7 Spont Abs. https://t.co/O2GT1BKiMT
21 Jul 2016 Social BMS has a new autoinjector for abatacept (ORENCIA) called "ClickJect" w/ 15 sec delivery duration https://t.co/6QHIqK51Pj
18 Jul 2016 Social Samsung Bioepis has filed its application for its Humira biosimilar with the European Medicines Agency https://t.co/bcfaJA2eTN
18 Jul 2016 News Will Patent Extensions Delay Biosimilar Arrivals?
15 Jul 2016 News ORBIT Study Shows Rituximab is Non-Inferior to TNF Inhibitors in Biologic Naive Patients
14 Jul 2016 News FDA Approves Xiidra (Lifitegrast) for Dry Eyes
13 Jul 2016 Social 7/12 FDA Arthritis Adv Committee voted 26-0 approve Amgens ADA biosimilar(ABP-501; today voted 20-0 to approve Sandoz ETN biosimilar GP2015
11 Jul 2016 Social 234 RA pts Tx w/ Rituxan x 28 mos. w/ retention rate of 57%. D/C assoc w/ higher age, SJC, no concomitant MTX use https://t.co/QRLR9mgP84