Monday, 09 Dec 2019


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17 Apr 2019 Social Lateral wedge insoles are often used medial knee OA. Study of 63 preselected pts shows a significant pain reduction (vs neutral soles) but mean difference was 0.7 on 0–10 scale; thus benefitting only a minority of pts
13 Nov 2019 Social RT @philipcrobinson: It's Dr. Paul Sufka @psufka talking about methotrexate and prednisone for Hand osteoarthritis…
01 Aug 2016 Social Early RA pts higher fracture risk w/ pred >15mg/d & >6400mg total. Fx risk 29% lower 60-182 d after d/c prednisone
22 Feb 2018 Social Checkout #RWCS video of Dr. Mark Genovese has he gives a 2018 update on osteoporosis from the 2018 RWCS meeting in Maui
02 Jun 2015 Social 5814 Medicare pts Rx w/ biologic + Denosumab or Zolendronic acid. Similar hosp infx rates were seen 14.9 v 13.9/100PY
19 Nov 2018 Social 80 overweight & obese pts w/ mild to moderate Knee OA Rx in RDBPCT showing garlic 1000 mg/D significantly lowers pain scores, resistin levels (but not TNF). Garlic may work by effects on MMPs, cytokines? shown to lower CRP levels
06 Apr 2018 Social Clinic study finds CT scan evidence of sacroiliitis in 15-16.9% of316 IBD pts vs only 5.6% of controls (no LBP GU pts); but only 5% of IBD SI pts were referred to Rheumatology.
01 Jul 2015 Social RT @DrPetryna:When "do not harm" comes handy - the overdiagnosis of osteoporosis
07 Oct 2016 Social Injection of nanoparticle peptides carrying siRNA that inhibit NF-κB may benefit osteoarthritic joints
05 Feb 2016 Social Michaelangelo did some of his best work while dealing with osteoarthritis of the hands.
07 Nov 2017 Social RT @_connectedcare: Recall the WHOLE joint involvement in OA, not just cartilage #ACR17 @RheumNow
11 Aug 2019 Social Osteoarthritis Iniative study of 3053 #OA pts shows worsening in health related quality of life is most rapid with Female gender, higher BMI, smoking, knee pain, and lower income at baseline. Rapid progressors had higher risk of TKR (HR 6.2;CI 3.6–10.7)
16 May 2018 Social Study from NYU and Emory shows that orders for MSK imaging were highest amongst Ortho Orthopedic surgery 37.6% (most knee imaging) Internal medicine 20.2% Family practice 14.8% Emergency medicine 7.9% Rheumatology 5.7% (most hand, 2nd in US)
26 Dec 2016 Social 48,867 Total hip arthroplasties: 1 yr risk of prosthetic Jt infx is 0.53% and hip revision was 1/44.
17 Jul 2018 Social Amgen and UCB have re-filed for FDA approval of osteoporosis drug romosozumab one year after a complete response letter citing CV risks. New data includes 7,180 ph3, 4,093 ph3 and a 245 pt male OP trial.
31 Jan 2019 Social RCT of Vitamin D in 379 elderly UK adults aged ≥70 y (48% women) give either 12,000 IU, 24,000 IU, or 48,000 IU. There was no ΔBMD, but parathyroid hormone decreased in all 3 groups (significantly betw 48,000 and 12,000-IU groups (P < 0.01).
22 Aug 2019 Social RCT of 139 knee OA pts given either curcumin 500-mg tid or diclofenac 50-mg bid. At days 14 and 28 both had similar improvement in pain and KOOS score; but curcumin had better tolerance, less GI sxs and H2 blocker use.
26 Mar 2016 Social Women are 1.5-2x more likely than men to have ACL tears - estrogen is key. F on birth control have less ACL surgery
16 Jun 2018 Social Dr. David Felson shows bone marrow lesions correlate well with pain of osteoarthritis, and may improve either treatment. from #EULAR SP0152
19 Apr 2017 Social In animal models, high fat, high carbohydrate diet (junk food) promotes cartilage damage and osteoarthritis.