Monday, 16 Sep 2019

Bone/OP&OA

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18 Jan 2019 ACR Video QD Video - Non-Traumatic Hemarthrosis
17 Jan 2019 News FDA Panel Backs Approval of Romosuzumab for Osteoporosis
10 Jan 2019 News Heberden’s Nodes Predict Knee OA Progression
09 Jan 2019 Social FDA has approved a single-injection hyaluronic acid (Durolane – Bioventus) and an ER formulation of the synthetic corticosteroid triamcinolone acetonide (Zilretta – Flexion) for intra-articular (IA) treatment of osteoarthritic knee pain. https://t.co/7rgsflNMVq
09 Jan 2019 News NEJM Review - Glucocorticoid-Induced Osteoporosis
04 Jan 2019 Social Finnish followup study of 68,800 hip fracture pts w hip surgery finds 4.6% w/ complications - esp with heavy alcoholism (HR 1.38); Parkinson’s (1.22); osteoarthritis (2.02); rheumatic Dz (1.44); those w/ depression/psychosis, operative delay, prior THR https://t.co/StahnHXRuZ
03 Jan 2019 Social Chronic Urticaria associated with a 23% higher risk of osteoporosis, irrespective of steroid use. Population study from Israel compared 11,944 Chr urticaria w/ 59,829 controls. (HR = 1.23, 95% CI 1.10–1.37, p <0.001) https://t.co/eSq4BPV2J4
03 Jan 2019 News Uncertain Long Term Efficacy in Trials of Knee Osteoarthritis
27 Dec 2018 Social PLEASE- stop trying Plaquenil, DMARDs, biologics in Hand OA - they dont work!!. My best regimen is: simple analgesics (acetaminophen 1950 mg qd) plus 2.5 mg prednisone, hand OT, and painful PIP/DIP immobilization with 2inch Cohesive tape x 14days https://t.co/I6JvgXuAo2
20 Dec 2018 News Zolendronate Protects Against Fracture in Osteopenia
17 Dec 2018 Social Metanalysis of 24 PPI studies, 319,568 hip fracture pts, suggests PPIs associated with a greater risk of hip fracture (RR 1.20, 95% CI 1.14–1.28, p < 0.0001) and may be greater with higher dose (RR 1.30, 95% CI 1.20–1.40, p < 0.0001). https://t.co/nbiEIPRaXg
03 Dec 2018 News Dendrimer Nanocarrier Delivers IGF-1 to Degenerative Cartilage
02 Dec 2018 Social Bisphosphonate safety review — risk of Atypical Femoral Fracture is 1/1000 and risk of osteonecrosis of the jaw is 1/10,000. One-third of IV zolendronic acid pts will have arthralgia/myalgias or flu like sxs. https://t.co/80xBkZlKgn
28 Nov 2018 Social Claims data study from Germany looked at OA of hip or knee in adults > 60 yrs finding 595,754 pts (mean 75 yrs; 70% female) Dx with OA (21.8%); 63% received analgesics, higher with increasing age. PT in 43.1% and 5.3% w/ joint replacement in 2014. https://t.co/shLSlDeO9h
27 Nov 2018 Social Bisphosphonate safety review - risk of Atypical Femoral Fracture is 1/1000 and risk of osteonecrosis of the jaw is 1/10,000. One-third of IV zolendronic acid pts will have arthralgia/myalgias or flu like sxs. https://t.co/80xBkZlKgn
26 Nov 2018 Social Metanalysis shows DMARDs (6 studies) and biologics (5 studies) offer NO clinically significant benefit compared with placebo in Osteoarthritis. https://t.co/fNGVzuNQNo
21 Nov 2018 News Low Risk of Serious Complications with Meniscectomy
19 Nov 2018 Social 80 overweight & obese pts w/ mild to moderate Knee OA Rx in RDBPCT showing garlic 1000 mg/D significantly lowers pain scores, resistin levels (but not TNF). Garlic may work by effects on MMPs, cytokines? shown to lower CRP levels https://t.co/bg5nwzUpJe https://t.co/us0uBLdCau
13 Nov 2018 News Pre-Diabetes Associated Risk for Arthritis, Obesity and Physical Inactivity
05 Nov 2018 News Controversial New Super Opioid Approved by FDA