Friday, 22 Jun 2018

Drug Safety

Datesort ascending Type Title Save
21 Jun 2018 News NSAID Use Around Conception Increases Miscarriage Risk
18 Jun 2018 Social Checkout the EULAR Day 4 podcast on RheumNow, iTunes, etc. https://t.co/GCFJNK6vyT
17 Jun 2018 News Could Measuring Drug Levels with TNF Treatment Hurt Your Patients?
17 Jun 2018 Social RT @RonanTKavanagh: Nice summary of Checkpoint inhibitor immunologic side effects of relevance to rheumatologists from @zandbelt . https://…
16 Jun 2018 Social RT @LCalabreseDO: Beautiful study by Kostine suggesting IrAEs indicate + ant- tumor effect at #eular2018 Cancer Therapies Inducing Immune-R…
16 Jun 2018 News Methotrexate Update
15 Jun 2018 Social RT @DrPetryna: #EULAR18 @RheumNow ABST op0241 tocilizumab may reduce the incidence of vascular complications in TAkayasu Arteritis. Failur…
15 Jun 2018 Social RT @pkiely500: #EULAR2018 Relative risk of post surgical infections in bDMARD users finds no difference between MOA but picks up co-prescri…
15 Jun 2018 ACR Video Dr. Olga Petryna at EULAR2018 Discusses Pregnancy Outcomes with Secukinumab
14 Jun 2018 Social RT @DrPetryna: #EULAR18 @RheumNow ABST thu0294 5year aremilast update: improved PASI-50 65.8% (98/149) & PASI-75 43.6% (65/149). 62.4% of…
14 Jun 2018 Social RT @RonanTKavanagh: Allanor (EUSTAR) oral Retrospective multi centre study of Rituximab for SSc. 248 patients. Mean follow up 2.4 yrs. Imp…
14 Jun 2018 Social RT @Janetbirdope: When you stop adalimumab you are still on it for MONTHS THU0211 poster showed novel TNFI assay showing still bound TNFI…
13 Jun 2018 News Cancer Therapies Inducing Immune-Related Adverse Events (irAEs)
01 Jun 2018 Social NSAIDs may reduce risk of certain cancers, esp colorectal CA. But NSAIDs combined with phosphatidylcholine is superior to NSAIDs alone in animal models at preventing colon cancer https://t.co/Glgi21Ealg
01 Jun 2018 Social In RCTs, among 1157 ulcerative colitis pts receiving tofacitinib, 65 (5.6%) developed herpes zoster, 11 multidermatomal & 1 HZ encephalitis. HZ=4.07 with higher risk in elderly, Asians, prior TNFi failure & tofa 10 mg bid. https://t.co/LsPGIrzDvu
31 May 2018 Social CMAJ reports on a Canadian population study of 290,939 girls 12–17 yrs who received quadravalent HPV vaccine with no increased risk of subsequent autoimmune disease (eg, Graves, Bells, JIA, SLE, AIHA, etc) https://t.co/jtJBDlE6jv
27 May 2018 Social Dr Ridker announced the NIH stopped enrolling the CIRT trial; MTX vs PBO in high risk (non-RA) pts looking at CV outcomes. DSMB rec. stopping after 4,786/7000 enrolled, not for safety, but because of enough efficacy data accrued. Look for results in 11/18 https://t.co/n4PGybItkS
24 May 2018 Social Paul Ridker, MD announced the NIH stopped enrolling the CIRT trial; MTX vs PBO in high risk (non-RA) pts looking at CV outcomes. DSMB rec. stopping after 4,786/7000 enrolled, not for safety, but because of enough efficacy data. Look for results in 11/18 https://t.co/n4PGybItkS
14 May 2018 Social RheumNow Wk in Review is up; Nonadherence and Atronomic Costs. Listen to the podcast on iTunes or here https://t.co/fvuI23Oez6 or watch the videocast https://t.co/Mks5i6XVHm
09 May 2018 Social In an animal model of induced large vessel vasculitis, in vivo Rx w/ tofacitinib reduced JAK2 & JAK 2 cytokine signaling and suppressed tissue-resident memory T cells and vasculitic pathology. https://t.co/7JIMbryFxo