Friday, 16 Feb 2018

Drug Safety

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11 Feb 2018 Social The RheumNow Wk in Review is up! Dr. Jack Cush discusses RWCS mtg, uricase exercise capillaroscopy & manpower. https://t.co/2WWmWNEL7G or listen to the podcast https://t.co/PgyBRjBq9w
10 Feb 2018 Social Dr Mark Genovese #RWCS - the rate of venous thromboembolic everts with baricitinib exposure appears to be 0.5 events per 100PY (basically the same rate seen in RA alone 0.5/100 PY) https://t.co/fRvLpHuDFP
09 Feb 2018 Social RT @uptoTate: Tofa 10mg BID may work for UC. Drs. Kavanaugh and Ruderman. #RWCS @RheumNow https://t.co/LE3tbTaKbF
04 Feb 2018 Social Risk factors for retinal toxicity associated with hydroxychloroquine include longer duration of HCQ use [adj OR 4.71], higher daily dose (3.34), presence of kidney disease (8.56) https://t.co/p8M4ezWLvG.
01 Feb 2018 Social Risk factors for retinal toxicity associated with hydroxychloroquine include longer duration of HCQ use [adj OR 4.71], higher daily dose (3.34), presence of kidney disease (8.56) https://t.co/A6sDsudCRq.
30 Jan 2018 News ACIP Guidelines on H. Zoster Vaccination Updated
27 Jan 2018 Social RheumNow Wk in Review is up. Discussing MPO bronchiectasis, $$ biologics, comorbidity in myositis, secondary TNF failure & ADAbs. Listen here https://t.co/ti9vRQrNaE Watch there https://t.co/TnC5Jg5knN
26 Jan 2018 News Higher Fracture Risk with PMR and GCA
26 Jan 2018 Social Bosentan may be effective in treating cutaneous ulcers with Anti-MDA5 Dermatomyositis. https://t.co/c5C1Vi5LVh
24 Jan 2018 Social Golimumab fails in pJIA - a randomised double-blinded placebo-controlled withdrawal trial 154 of 173 polyarticular JIA pts responded to golimumab; but in the withdrawal phase, flare rates were same with GOL (41%) & PBO (41%).
22 Jan 2018 News Problems with Biologic Drug Storage
19 Jan 2018 Social RheumNow Wk in Review is up! Info on Humira $$, PM/DM infections, burnout, biologics, Still's and weight loss. Listen here https://t.co/nQ72HrwwQA or View it here https://t.co/Z5qawcztkD
18 Jan 2018 News Prevention of HBV Infection: How Are We Doing?
17 Jan 2018 Social NY Times article reports 2015 price of 2 syringes of Humira is $2669 in USA; $1362 in UK; $1253 in Spain; $822 in Switzerland and $552 in South Africa. https://t.co/ulZFTxsRBU
11 Jan 2018 Social DMARD Tip: Leflunomide has a 1/2 life of nearly 20days. Once pt improved w/ 20mg/d (~6-12 wks) I switch dosing to once weekly, often less total mg (eg, LEF 4-6 tab q friday (80-120mg/wk). Monitoring and risks are same. https://t.co/dP7EooQEKz
11 Jan 2018 News B Cell Changes Predict Autoimmunity with Checkpoint Inhibitors
10 Jan 2018 News Ibuprofen’s Anti-androgenic Effect May Result in Hypogonadism in Males
09 Jan 2018 Social Gabapentinoid use steadily rose from 1.2% of adults in 2002 to 3.9% in 2015 https://t.co/seC0thDIX9
06 Jan 2018 Social RT @dhjutsw1: ICYMI: AbbVie raised Humira by another 9.7% percent this month, roughly 4.5 times the inflation rate. "For the drug industry,…
06 Jan 2018 Social Study of ~300k Canadian pregnancies (1998-2015) finds 51 1st Trimester exposures to Arava & 21 w/ 2nd/3rd Tri exposure; no incr risk of spont Abortion (11), Malformations (5), prematurity (7) or LBW (8) https://t.co/jsVXdvQGEM