Friday, 18 Oct 2019

Drug Safety

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05 Jun 2019 Social CDC has updated its recommendations for TB testing of health care personnel. All HCP should be tested initially but after TB risk assessment, there is no need for routine or serial TB testing in the absence of exposure or ongoing risk of TB.
18 Aug 2016 Social Great rheumatology primer on sorting out tropical mosquito related viruses from @LCalabreseDO & CCF
23 Mar 2016 Social Statin use is assoc. w/ a 21% increased risk of skin cancer (NMSC) - data from >130K postmenopausal women (WHI)
29 Apr 2017 Social #SOTA2017 Dr. Bingham Most common joints are large - knees ankels shoulders, many w/ Small - MCPs PIPs wrists, ReA in 2 pts
03 Oct 2017 Social `07 JIA pts followed for 3 yrs on Biologics- 25% (35) had Serious/Opportunistic infx. range 10.6-14.8/100py
11 Nov 2017 Social RT @NYTHealth: Fentanyl, not heroin, drove 2016 surge in drug-overdose deaths, C.D.C. says.
24 Aug 2018 Social RT @RheumNow: Which Anti-Rheumatic is shown/known to be a clear teratogen and thus pregnancy must be prevented/avoided when taking this dru…
19 Jan 2019 Social JAMA study shows that when drug companies increased their opioid marketing budgets by just $5.29 per 1,000 population, the number of MD opioid prescriptions went up 82% and opioid deaths increased 9%.
26 Jun 2019 Social ORAL Strategy, 216 or 18.8% received the Zostvax vaccine. Overall, 18 patients (1.6%) developed HZ (vaccinated=3; non-vaccinated=15). HZ IRs (95% CI) were 1.1 (0.3, 2.9), 2.3 (1.0, 4.6), and 1.7 (0.6, 3.7) for tofa monotherapy, tofa+MTX, & ADA+MTX, resp.
02 Sep 2016 Social @RonanTKavanagh Such sites cull medwatch reports, but dont verify. Accuracy is low. TNFi rarely reported w/ renal AE
25 May 2015 Social 10,763 AS pts from Taiwan showed long-term Cox2 or NSAIDs had fewer CV events & short term NSAIDs had incr CV events
29 Apr 2017 Social RT @DrRachelTate: "Hepatitis C is now a curable disease." L. Calabrese, DO @RheumNow #SOTA2017
09 Oct 2017 Social HCQ decreases CV events, DM 41% & benefits metabolic profile in RA- HCQ useful add on w/ other DMARDs @DrPetryna
27 Sep 2018 Social Systematic review examined 10 studies, 1156 patients with undifferentiated (UA) or arthralgia & showed that DMARD/steroids did not reduce the risk of RA in arthralgia only pts, but use in UA significantly reduced the risk (OR 0.73; 95% CI 0.56 to 0.97)
03 Mar 2019 Social QD Clinic - Dysgeusia? | RheumNow -A DMARD med leaving a bad taste in the mouth
28 Jul 2019 Social Committee for Medicinal Products for Human Use of the European Medicines Agency (EMA) has adopted a negative opinion on Application for romosozumab (Evenity) for the treatment of severe osteoporosis (by Amgen & UCB); an appeal is planned
20 Sep 2016 Social Periprosthetic Fx after Hip Replacement is higher in women, older, RA pts, revision surgery, AVN hx & osteoporosis
15 Jul 2015 Social 4 Sending pts to internet for info, 5 Not using graphics, 6 Cultural awareness/sensitivity, 7 info in wrong language
26 May 2017 Social RT @CCalabreseDO: debunking vaccine myths. very important! @healiorheum @rheumnow
20 Dec 2017 Social The problem of nonadherence to meds, not filling Prescriptions is a big one. NYT reviews it stating that the only promising solution is cheaper meds