Friday, 18 Oct 2019

Drug Safety

Date Typesort ascending Title Save
23 Jan 2017 Social Study of 565k people shows chronic PPI has a nearly 2 fold risk of C. dificile & 4 fold risk of campylobacter infxn
20 Dec 2017 Social The problem of nonadherence to meds, not filling Prescriptions is a big one. NYT reviews it stating that the only promising solution is cheaper meds
26 Jun 2019 Social ORAL Strategy, 216 or 18.8% received the Zostvax vaccine. Overall, 18 patients (1.6%) developed HZ (vaccinated=3; non-vaccinated=15). HZ IRs (95% CI) were 1.1 (0.3, 2.9), 2.3 (1.0, 4.6), and 1.7 (0.6, 3.7) for tofa monotherapy, tofa+MTX, & ADA+MTX, resp.
19 Jan 2019 Social JAMA study shows that when drug companies increased their opioid marketing budgets by just $5.29 per 1,000 population, the number of MD opioid prescriptions went up 82% and opioid deaths increased 9%.
06 Mar 2016 Social New AAOS studies highlight the need to avoid intarticular steroids in the 3 mos prior to joint replacement surgery.
24 Aug 2018 Social RT @RheumNow: Which Anti-Rheumatic is shown/known to be a clear teratogen and thus pregnancy must be prevented/avoided when taking this dru…
19 Feb 2017 Social Dr Mahadevan #RWCS17 on Eosinophilic Esophagitis. Rx with PPI, elemental dirt
28 Mar 2017 Social RT @LCalabreseDO: About one in five Americans with RA gets tested for hepatitis B WHY? because ACR GUIDLINES ARE IN…
06 Jul 2016 Social Guidance on when and how to vaccinate against Herpes Zoster delivered by Dr Cush at the RWCS 2016 conference
28 Jul 2019 Social Committee for Medicinal Products for Human Use of the European Medicines Agency (EMA) has adopted a negative opinion on Application for romosozumab (Evenity) for the treatment of severe osteoporosis (by Amgen & UCB); an appeal is planned
03 Mar 2019 Social QD Clinic - Dysgeusia? | RheumNow -A DMARD med leaving a bad taste in the mouth
06 Nov 2017 Social RT @psufka: Oral corticosteroids increase risk of preterm birth in all trimesters (regardless DMARD exposure)#ACR17 @rheumnow #1313
27 Sep 2018 Social Systematic review examined 10 studies, 1156 patients with undifferentiated (UA) or arthralgia & showed that DMARD/steroids did not reduce the risk of RA in arthralgia only pts, but use in UA significantly reduced the risk (OR 0.73; 95% CI 0.56 to 0.97)
28 Apr 2017 Social BSR meeting reports study of 19,162 pts on a biologic shows risk of opportunistic infections to b 1/1000 over 5+yrs
06 May 2015 Social Under pressure, @US_FDA to hold public meeting on off-label use.  #lol
29 Apr 2017 Social #SOTA2017 Dr Bingham John's Hopkins case experiences, pts tx for metastatic refractory cancer with ICI
10 May 2015 Social Prospective study of 113 pregnancies fathered by men on MTX vs 412 nonExposed, showed no increase in birth defects
13 Sep 2017 Social Stelara doesnt cause TB; but Stelara use in a high risk "TB Land"(Taiwan) is assoc w/ seroconversion 7.3% (new infx)
30 Nov 2016 Social RT @CCalabreseDO: Study shows that only 1/5 of seniors receive shingles vaccine
10 Nov 2017 Social RT @DrBhana: drug induced ANCA associated vasculitis #ACR17