Monday, 16 Sep 2019

Drug Safety

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05 Jul 2019 Social RT @RheumNow: Dr. Kevin Winthrop - Expert Advice on TB Testing and Treatment from #EULAR2019
28 Jun 2019 Social RheumNow Podcast is UP! Discussions of MTX stomatitis, Loading doses, PPD Shortage, infection risk from steroids or THR/TKR and more. Watch it here>> or listen in on iTunes or SoundCloud >>
27 Jun 2019 Social Metanalysis of 3954 studies, 20 RCTs examined MTX toxicity and found the prevalence of alopecia to be 1- 4.9% and the prevalence of stomatitis to be between 5.7-8%
26 Jun 2019 Social ORAL Strategy, 216 or 18.8% received the Zostvax vaccine. Overall, 18 patients (1.6%) developed HZ (vaccinated=3; non-vaccinated=15). HZ IRs (95% CI) were 1.1 (0.3, 2.9), 2.3 (1.0, 4.6), and 1.7 (0.6, 3.7) for tofa monotherapy, tofa+MTX, & ADA+MTX, resp.
20 Jun 2019 Social Methotrexate assoc. lymphoproliferative disorders (LPDs), is a rare disorder that resolves w/ MTX withdrawal (in 3-10mos). Most common path was diffuse large B-cell lymphoma and 45-77% had Epstein-Barr virus encoded RNA positivity.
19 Jun 2019 ACR Video RNL Preview with Dr. Lisa Sammaritano: Anti-Rheumatic Drug Use with Pregnancy
17 Jun 2019 Social RT @tuna0sashimi: MTX withdrawal in tofacitinib MR 11mg ORAL shift 1y study @week 24, MTX blindly withdrawal for pt achieved LDA (CDAI <=10…
17 Jun 2019 Social RT @tuna0sashimi: Please please publish this so we can quote it for our patients RT @CreakyJoints: Reassuring news about hair loss and meth…
06 Jun 2019 Social FDA sent an "untitled"letter to "R3 Stem Cell" for touting birth tissue products as Rx for ailments (without scientific evidence). FDA also won a case against "US Stem Cell clinics" for adulterated & misbranded stem cell products
06 Jun 2019 Social Transparency is coming? The Prices will soon be Included in TV Drug Ads. HHS Secretary Alex Azar has finalized regulations requiring drug companies to disclose list prices of medications costing more than $35 for a month’s supply.
05 Jun 2019 Social CDC has updated its recommendations for TB testing of health care personnel. All HCP should be tested initially but after TB risk assessment, there is no need for routine or serial TB testing in the absence of exposure or ongoing risk of TB.
04 Jun 2019 Slide of the day FDA Reviews Febuxostat CV Safety
02 Jun 2019 Social RheumNow Podcast is up! What to monitor with RTX therapy. Watch here> or listen to the podcast on iTunes or SoundCloud>>
29 May 2019 Social FDA is seeking public input into CBD - cannabidiol - and will be holding a public hearing on CBD this friday May 31st.
29 May 2019 Social Dr. Madelaine Feldman's outstanding lecture on Drug Costs in America: The Bad, the Worse and The Despicable, is available for free at RheumNow Live On Demand at Check it out - you'll be glad you did. #rheumed #rheum
24 May 2019 Slide of the day New Shingrix Vaccine
24 May 2019 ACR Video RheumNow Live Preview with Dr. Eric Matteson (History of Steroids)
15 May 2019 ACR Video RheumNow Live Preview with Dr. Jack Cush (Infection Prevention & Management with Newer Agents)
14 May 2019 News Methotrexate Use Not Linked to Interstitial Lung Disease in RA
13 May 2019 Social PCSK9 inhibitors (ie, Repatha) can safetly be used in Statin-induced HMGCR+ myopathy pts . 8 pts given PCSK9 inhib for hyperlipidemia, showed no Sx worsening, CK levels dropped (956±1137 IU/L to 419±393 IU/L) & HMGCR Ab titers decreased; 2/8 improved