Monday, 26 Aug 2019

Drug Safety

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18 Aug 2016 Social Great rheumatology primer on sorting out tropical mosquito related viruses from @LCalabreseDO & CCF https://t.co/j4AdfSQX7P
23 Mar 2016 Social Statin use is assoc. w/ a 21% increased risk of skin cancer (NMSC) - data from >130K postmenopausal women (WHI) https://t.co/2uxJOC719Y
08 Sep 2018 Social RheumNow Week in Review is up! This week the sunshine folder & ugly tie rack! Watch the video here https://t.co/Lb0mFGPTHc or try the podcast on iTunes in your car or on Android Auto in your car on Stitcher or https://t.co/Lb0mFGPTHc
02 Dec 2016 Social J&J/Dupuy hit with $1billion verdict to 6 plantiffs who recv metal on metal THR; appeal planned w/ >8000 more suits https://t.co/OBuirKGvO7
18 Nov 2018 Social The RheumNow Podcast is up! THe Heartbreak of CIRT & MTX. view it https://t.co/jTQUFWJkNJ or listen to the Podcast on iTunes or here https://t.co/2w0vNA7VmY
18 Jul 2019 Social anti-MDA5+ amyopathic dermatomyositis (ADM) with ILD is severe and refractory. NEJM letter reports on 18 ADM Rx w/ tofacitinibs who showed better 6 mo survival (100% vs 78%) (P=0.04) and improved ferritin, FVC, DLCO, & CT Chest over time. https://t.co/lsVGPxChoO
14 Sep 2017 Social No difference in folic acid low dose vs high dose use with regard to hepatotoxicity of MTX. https://t.co/fnqqqwyE23
29 Dec 2017 Social RT @AngusWorthing: “We could give [our new drug] away for free and … it would still be more economically advantageous” for insurers and PBM…
14 Aug 2015 Social Do you have the means of formal clinical med reviews w/ pharmacist? They can improve adherence, compliance, outcomes http://t.co/HgShWp94Gp
27 Jan 2018 Social RheumNow Wk in Review is up. Discussing MPO bronchiectasis, $$ biologics, comorbidity in myositis, secondary TNF failure & ADAbs. Listen here https://t.co/ti9vRQrNaE Watch there https://t.co/TnC5Jg5knN
29 Apr 2017 Social #SOTA2017 Dr. Bingham Most common joints are large - knees ankels shoulders, many w/ Small - MCPs PIPs wrists, ReA in 2 pts
20 Jun 2015 Social Drug Safety Bulletin: EULAR 2015 Safety Reports @RheumNow, TNFi and Biologics lower risk of Sepsis & death after SIE http://t.co/aMu1hNXR0K
05 May 2016 Social BMJ study shows >250,000 deaths/Yr in US due to medical errors – making it the 3rd leading cause of death https://t.co/IviNCTvaaL
22 Oct 2018 Social RT @KDAO2011: Great Pearl by Dr J Kremer: if a patient complains about hair loss with MTX, add leucovorin (but don’t administer same day as…
05 Nov 2017 Social RT @_connectedcare: Large trial, long fu. Celecoxib does NOT cause more CVS issues than Naproxen or Ibuprofen #ACR17 @rheumnow https://t.co…
03 Oct 2017 Social `07 JIA pts followed for 3 yrs on Biologics- 25% (35) had Serious/Opportunistic infx. range 10.6-14.8/100py https://t.co/8kad5PmLKR
26 Feb 2018 Social Of 134 RTX treated pts (mean 79 mos), 23 (17%) developed Hypogammaglobulinemia after a mean 64 mos & assoc w/ 4x risk of severe infections. Gammaglobulin <8 g/L at baseline was a predictor of hypogamma (HR 7.34), but MTX was protective (HR 0.26) https://t.co/AMOtNAUeXR
06 May 2017 Social FDA Guide to Drug Safety. Black Box Warning; appears on drugs label to alert of serious or life-threatening risks https://t.co/1gNk2RB5C0
01 Oct 2016 Social Rates of Septic arthritis increased 43% in UK (5.5-->7.8/100k) over last 15yrs, especially in elderly >75. https://t.co/Ol5ZSZu7bb
07 Jun 2016 Social Spanish pts on TNFi note 2 fold higher SAE/mortality risk in RA than PsA; w/ more infx, CVS, Pulm, Infusion AE in RA https://t.co/ltcErtY64p