Friday, 17 Jan 2020

Drug Safety

Date Typesort ascending Title Save
14 Mar 2017 Social VA study 748 RA pts w/ HCV, ALT incr only in 3.4%; Hepatotoxicity more common w/ Biologic than cDMARD(4.8 v 2.3%)
15 Aug 2017 Social Consumer reports drug safety questions for older folks:1) safe for my age? 2) will lower doses do? 3) is Rx needed?
20 Jun 2015 Social Drug Safety Bulletin: EULAR 2015 Safety Reports @RheumNow, TNFi and Biologics lower risk of Sepsis & death after SIE
18 Jul 2019 Social anti-MDA5+ amyopathic dermatomyositis (ADM) with ILD is severe and refractory. NEJM letter reports on 18 ADM Rx w/ tofacitinibs who showed better 6 mo survival (100% vs 78%) (P=0.04) and improved ferritin, FVC, DLCO, & CT Chest over time.
29 Dec 2017 Social RT @AngusWorthing: “We could give [our new drug] away for free and … it would still be more economically advantageous” for insurers and PBM…
14 May 2018 Social RheumNow Wk in Review is up; Nonadherence and Atronomic Costs. Listen to the podcast on iTunes or here or watch the videocast
23 Mar 2016 Social Statin use is assoc. w/ a 21% increased risk of skin cancer (NMSC) - data from >130K postmenopausal women (WHI)
28 Mar 2017 Social RT @LCalabreseDO: About one in five Americans with RA gets tested for hepatitis B WHY? because ACR GUIDLINES ARE IN…
15 Jul 2015 Social 4 Sending pts to internet for info, 5 Not using graphics, 6 Cultural awareness/sensitivity, 7 info in wrong language
28 Jul 2019 Social Committee for Medicinal Products for Human Use of the European Medicines Agency (EMA) has adopted a negative opinion on Application for romosozumab (Evenity) for the treatment of severe osteoporosis (by Amgen & UCB); an appeal is planned
26 Oct 2018 Social RT @ARD_BMJ: New ACR guidelines for treatment management during pregnancy in patients with rheumatic diseases #ACR18 > AM…
02 Sep 2016 Social @RonanTKavanagh Such sites cull medwatch reports, but dont verify. Accuracy is low. TNFi rarely reported w/ renal AE
06 Nov 2017 Social RT @psufka: Oral corticosteroids increase risk of preterm birth in all trimesters (regardless DMARD exposure)#ACR17 @rheumnow #1313
28 Apr 2017 Social BSR meeting reports study of 19,162 pts on a biologic shows risk of opportunistic infections to b 1/1000 over 5+yrs
30 Nov 2018 Social The RheumNow Podcast is Up! To Needle or Not to Needle; Watch or listent to the weekly news and review
04 Jul 2018 Social "Prednisone is the best drug we have, and prednisone is the worst drug we have"- Peter A. Merkel, MD
20 Sep 2016 Social Periprosthetic Fx after Hip Replacement is higher in women, older, RA pts, revision surgery, AVN hx & osteoporosis
23 Nov 2015 Social 10 ways to avoid FATAL MTX errors: give folate, avoid bactrim/augmentin, Rx only 30d @ a time, avoid w renal failure
20 Dec 2019 Social Gabapentin and baclofen use, misuse, toxicity, & suicide attempts increased in the United States since 2013. Gabapentin use increased 72% and baclofen increased 37% from 2014 to 2017.
08 Nov 2017 Social RT @synovialjoints: The use of low dose aspirin as primary prevention of CV events in RA had similar risk of major NSAID toxicity and MACE…