Friday, 15 Dec 2017

Drug Safety

Datesort ascending Type Title Save
30 Oct 2017 Social 20 pts early diffuse SSc Rx w/ MMF + PBO or belimumab. Belim. trended to better Rodnan skin scores but NS (-10 v -3)
27 Oct 2017 News CDC Endorses New Shingles Vaccine Over Zostavax
24 Oct 2017 Social British psoriasis registry shows SIE not incr w/ biologics ETN, ADA, UST (1.4-1.5/100PY) vs nonbiologic 1.4/100py
22 Oct 2017 Social RT @DrPetryna: CRIB:1/14 newborns had minim CZP levels, rest undetect,umb cord 3/15 +CZP -safe to cont CZP in pregnancy…
20 Oct 2017 News Hepatitis A Outbreak in San Diego
20 Oct 2017 Social At #APLAR2017 I taught how to manage post-MTX related CNS toxicity "the blahs" with weekly dextromethorphan 20-50mg given w MTX & day after
20 Oct 2017 Social At #APLAR2017 I taught how to manage MTX related oral ulcers & nausea with daily OTC vitamin A 8000 U every day = 70% effective
20 Oct 2017 Social Dr. Bijksma says U-ACT shows odds of achieving drug free remission was best with early use of TCZ+MTX in very early…
20 Oct 2017 Social U-ACT shows early TCZ (+/- MTX) is superior to MTX alone at sustained remission >6 most Iin very early RA patients
17 Oct 2017 Social Pilot trial 20 pt w/ DM/PM Rx w/ IV Abatacept; half improved; Bxs showed increased Foxp3+ Tregs.
16 Oct 2017 Social RT @philipcrobinson: This is very interesting, maybe abatacept works in inflammatory myositis from @ARD_BMJ
14 Oct 2017 Social RheumNow Wk in Review is Up! watch video or listen to the podcast. Please rate us at iTunes
13 Oct 2017 Social RT @RonanTKavanagh: Autoimmune thyroid disease as a possible S/E of Anti TNF agents. Didn’t know that. Til today. #…
13 Oct 2017 Social Anfibrotic effx of antiviral Nelfinavir shown to decr TGF-β1-mediated pulm fibrosis & myofibroblast differentiation
10 Oct 2017 Social 31465 on ULT, allopurinol assoc w/ 39% lower risk renal dz (HR 0.61 vs febuxostat). Higher doses = more protection
10 Oct 2017 Social 21 w/ Henoch Schonlein Purpura Rx w/ RTX: 20/21 achieved remission; w/ improved Proteinuria, BVAS, CRP; 35% relapsed
09 Oct 2017 Social Jan 1st CIGNA will stop covering Oxycontin - is this improved safety or another way to max $$$ &reduce company risk?
09 Oct 2017 Social HCQ decreases CV events, DM 41% & benefits metabolic profile in RA- HCQ useful add on w/ other DMARDs @DrPetryna
09 Oct 2017 Social Annual costs assoc w/ adverse drug events in US rose from $76.6 billion 1995 to >$177.4 bill 2000; hosp 70% of total
08 Oct 2017 Social RheumNOw Wk in Review is Up! Tof lymphoma risk, early Dx of RA, Preg & biologics, 2016 top 5 Rheumatology drugs.