Wednesday, 22 Jan 2020

Drug Safety

Date Typesort ascending Title Save
04 Jul 2018 Social "Prednisone is the best drug we have, and prednisone is the worst drug we have"- Peter A. Merkel, MD
25 May 2015 Social 10,763 AS pts from Taiwan showed long-term Cox2 or NSAIDs had fewer CV events & short term NSAIDs had incr CV events
06 Jul 2016 Social Guidance on when and how to vaccinate against Herpes Zoster delivered by Dr Cush at the RWCS 2016 conference
28 Jul 2019 Social Committee for Medicinal Products for Human Use of the European Medicines Agency (EMA) has adopted a negative opinion on Application for romosozumab (Evenity) for the treatment of severe osteoporosis (by Amgen & UCB); an appeal is planned
28 Mar 2017 Social RT @LCalabreseDO: About one in five Americans with RA gets tested for hepatitis B WHY? because ACR GUIDLINES ARE IN…
30 Nov 2018 Social The RheumNow Podcast is Up! To Needle or Not to Needle; Watch or listent to the weekly news and review
24 Aug 2018 Social RT @RheumNow: Which Anti-Rheumatic is shown/known to be a clear teratogen and thus pregnancy must be prevented/avoided when taking this dru…
15 Jul 2015 Social 4 Sending pts to internet for info, 5 Not using graphics, 6 Cultural awareness/sensitivity, 7 info in wrong language
06 Nov 2017 Social RT @psufka: Oral corticosteroids increase risk of preterm birth in all trimesters (regardless DMARD exposure)#ACR17 @rheumnow #1313
28 Apr 2017 Social BSR meeting reports study of 19,162 pts on a biologic shows risk of opportunistic infections to b 1/1000 over 5+yrs
19 Jan 2019 Social JAMA study shows that when drug companies increased their opioid marketing budgets by just $5.29 per 1,000 population, the number of MD opioid prescriptions went up 82% and opioid deaths increased 9%.
27 Sep 2018 Social Systematic review examined 10 studies, 1156 patients with undifferentiated (UA) or arthralgia & showed that DMARD/steroids did not reduce the risk of RA in arthralgia only pts, but use in UA significantly reduced the risk (OR 0.73; 95% CI 0.56 to 0.97)
20 Dec 2019 Social Gabapentin and baclofen use, misuse, toxicity, & suicide attempts increased in the United States since 2013. Gabapentin use increased 72% and baclofen increased 37% from 2014 to 2017.
06 Mar 2016 Social New AAOS studies highlight the need to avoid intarticular steroids in the 3 mos prior to joint replacement surgery.
02 Sep 2016 Social @RonanTKavanagh Such sites cull medwatch reports, but dont verify. Accuracy is low. TNFi rarely reported w/ renal AE
23 Jan 2017 Social Study of 565k people shows chronic PPI has a nearly 2 fold risk of C. dificile & 4 fold risk of campylobacter infxn
08 Nov 2017 Social RT @synovialjoints: The use of low dose aspirin as primary prevention of CV events in RA had similar risk of major NSAID toxicity and MACE…
14 Feb 2018 Social FDA grants priority review for Genentechs Rituxan for use in pemphigus vulgaris
25 Apr 2019 Social Danish study of 92 355 adults compared Fx rates between new users of denosumab (DEN) or alendronate - finds no advantage for DEN for hip Fx (aHR 1.08; 0.92-1.28) or any Fx (aHR 0.92; 0.83-1.02). Data doesnt support preference for DEN in high risk pts.
22 Mar 2016 Social FDA proposes ban on powdered gloves citing more adverse events, airway & wound inflammation & postsurgical adhesions