Wednesday, 20 Mar 2019

Drug Safety

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14 May 2018 Social RheumNow Wk in Review is up; Nonadherence and Atronomic Costs. Listen to the podcast on iTunes or here or watch the videocast
09 May 2018 Social In an animal model of induced large vessel vasculitis, in vivo Rx w/ tofacitinib reduced JAK2 & JAK 2 cytokine signaling and suppressed tissue-resident memory T cells and vasculitic pathology.
28 Apr 2018 Social RheumNow week in Review is up - FDA Showdown! Listen to the podcast on iTunes or here or watch the video that makes children cry
25 Apr 2018 Social Among 2619 RA patients, use of hydroxychloroquine (n 1212) was associated with a lower risk of CKD (10.3 vs 13.8 per 1000PY); thus HCQ assoc w/ a lower risk of incident CKD (HZ 0.64; 95% confidence interval, 0.45 to 0.90; P=0.01) & was dose dependent
23 Apr 2018 Social French open label study 46 Takayasu pts shows tocilizumab IV improves disease activity and reduces steroid use and relapse rates.
19 Apr 2018 News Tobacco Associated Deaths in the USA
18 Apr 2018 Social Do the RheumNow LIVE VOTE Survey: is DVT/PE Risk from Disease or Drugs? If youre a RHEUMATOLOGIST - please vote in our quick 4Q survey today
17 Apr 2018 Social RheumNow is doing a Survey on DVT/PE Risk from Disease or Drugs; If youre a RHEUMATOLOGIST - please vote in our quick 4Q survey today
16 Apr 2018 Social RheumNow LIVE VOTE for RHEUMATOLOGISTS - What causes VTE - drugs or disease. RHEUMS Vote here:
16 Apr 2018 News EMA to Review Methotrexate Overdose and Dosing Errors
16 Apr 2018 News MMWR: Cannabis Use in the Colorado Workers
15 Apr 2018 Social RT @SGottliebFDA: #FDA is taking new steps to encourage drug companies to include pregnant women in clinical trials, issuing a draft guidan…
13 Apr 2018 Social RheumNow week in review is up! Do you Dig Shingrix? Listen to podcast on iTunes, Apple Car play, Stitcher or watch it on the website
12 Apr 2018 Social In early arthritis clinics in Leeds and UK ERAS study (454 &895 pts), DMARD free remission seen in 15-9.4%; predictors included acute onset, short Sx duration, NO smoking, No Xray damage, Seronegativity, absent HLA shared epitope alleles
11 Apr 2018 Social Generic drugs became law in 1967 & grew w/ Hatch-Waxman Act of 1984. They currently comprise 2/3 of all prescriptions. Heres a nice review of Generics by a pharmacist, for patients.
07 Apr 2018 Social RT @philipcrobinson: Great data on tocilizumab and breast feeding
29 Mar 2018 News 2 Weeks Off Methotrexate OK for Flu Vaccine
22 Mar 2018 News Risk of Paternal Exposure to Anti-Rheumatic Drugs
20 Mar 2018 Social Pregnancy study from Quebec finds 51 Pregs exposed to leflunomide during 1st trimester; 21 during the 2nd/3rd trimesters but was not associated with an increased risk of congenital malformations, Spont Ab, low birth weight or prematurity
19 Mar 2018 Social Metanalysis of 9 studies examining antirheumatic drug effects on vaccination showed MTX & TNFi with no effect on influenza responses; but MTX may reduce pneumococcal responses; being on biologic or MTX should not deter from these vaccinations