Friday, 18 Jan 2019

Drug Safety

Datesort ascending Type Title Save
22 Feb 2018 News Equal Cardiovascular Risks in Hypertensive Patients Treated with Selective and Nonselective NSAIDS
21 Feb 2018 Social Dr. Hyman Zimmerman is famous for drug-induced hepatocellular injury plus jaundice conferring a 10% mortality rate. "Hy's Law" is used by the FDA to judge serious hepatotoxicity and risk of death; Requires evidence of jaundice and ALT/AST >3x ULN https://t.co/qu65fdGscf
21 Feb 2018 News ASCO/NCCN Guidelines for Checkpoint Inhibitor Immune-Related Adverse Events
16 Feb 2018 Social Pharmacovigilance using Twitter? A UK study compared glucocorticoid AE on Twitter vs UK MHRA regulatory system; in 3 yrs, Twitter Identified 20,210 Steroid AE, but only 3022 via MHRA. Twitter AE “common but not serious”, most being insomnia and weight gain https://t.co/T49kterWXS
15 Feb 2018 Social Lilly announces top line results of COAST-V trial showing the safety and efficacy of Taltz/ixekizumab (vs PBO vs adalimumab) in Ankylosing Spondylitis meeting primary and secondary endpoints (ASAS40) at 16 weeks. Resuts to likely be presented at EULAR https://t.co/0UBAjZTjDr
14 Feb 2018 Social FDA grants priority review for Genentechs Rituxan for use in pemphigus vulgaris https://t.co/e6uKQOf55f
11 Feb 2018 Social The RheumNow Wk in Review is up! Dr. Jack Cush discusses RWCS mtg, uricase exercise capillaroscopy & manpower. https://t.co/2WWmWNEL7G or listen to the podcast https://t.co/PgyBRjBq9w
10 Feb 2018 Social Dr Mark Genovese #RWCS - the rate of venous thromboembolic everts with baricitinib exposure appears to be 0.5 events per 100PY (basically the same rate seen in RA alone 0.5/100 PY) https://t.co/fRvLpHuDFP
09 Feb 2018 Social RT @uptoTate: Tofa 10mg BID may work for UC. Drs. Kavanaugh and Ruderman. #RWCS @RheumNow https://t.co/LE3tbTaKbF
04 Feb 2018 Social Risk factors for retinal toxicity associated with hydroxychloroquine include longer duration of HCQ use [adj OR 4.71], higher daily dose (3.34), presence of kidney disease (8.56) https://t.co/p8M4ezWLvG.
01 Feb 2018 Social Risk factors for retinal toxicity associated with hydroxychloroquine include longer duration of HCQ use [adj OR 4.71], higher daily dose (3.34), presence of kidney disease (8.56) https://t.co/A6sDsudCRq.
30 Jan 2018 News ACIP Guidelines on H. Zoster Vaccination Updated
27 Jan 2018 Social RheumNow Wk in Review is up. Discussing MPO bronchiectasis, $$ biologics, comorbidity in myositis, secondary TNF failure & ADAbs. Listen here https://t.co/ti9vRQrNaE Watch there https://t.co/TnC5Jg5knN
26 Jan 2018 News Higher Fracture Risk with PMR and GCA
26 Jan 2018 Social Bosentan may be effective in treating cutaneous ulcers with Anti-MDA5 Dermatomyositis. https://t.co/c5C1Vi5LVh
24 Jan 2018 Social Golimumab fails in pJIA - a randomised double-blinded placebo-controlled withdrawal trial 154 of 173 polyarticular JIA pts responded to golimumab; but in the withdrawal phase, flare rates were same with GOL (41%) & PBO (41%).
22 Jan 2018 News Problems with Biologic Drug Storage
19 Jan 2018 Social RheumNow Wk in Review is up! Info on Humira $$, PM/DM infections, burnout, biologics, Still's and weight loss. Listen here https://t.co/nQ72HrwwQA or View it here https://t.co/Z5qawcztkD
18 Jan 2018 News Prevention of HBV Infection: How Are We Doing?
17 Jan 2018 Social NY Times article reports 2015 price of 2 syringes of Humira is $2669 in USA; $1362 in UK; $1253 in Spain; $822 in Switzerland and $552 in South Africa. https://t.co/ulZFTxsRBU