Friday, 23 Mar 2018

Drug Safety

Datesort ascending Type Title Save
16 Oct 2017 Social RT @philipcrobinson: This is very interesting, maybe abatacept works in inflammatory myositis from @ARD_BMJ
14 Oct 2017 Social RheumNow Wk in Review is Up! watch video or listen to the podcast. Please rate us at iTunes
13 Oct 2017 Social RT @RonanTKavanagh: Autoimmune thyroid disease as a possible S/E of Anti TNF agents. Didn’t know that. Til today. #…
13 Oct 2017 Social Anfibrotic effx of antiviral Nelfinavir shown to decr TGF-β1-mediated pulm fibrosis & myofibroblast differentiation
10 Oct 2017 Social 31465 on ULT, allopurinol assoc w/ 39% lower risk renal dz (HR 0.61 vs febuxostat). Higher doses = more protection
10 Oct 2017 Social 21 w/ Henoch Schonlein Purpura Rx w/ RTX: 20/21 achieved remission; w/ improved Proteinuria, BVAS, CRP; 35% relapsed
09 Oct 2017 Social Jan 1st CIGNA will stop covering Oxycontin - is this improved safety or another way to max $$$ &reduce company risk?
09 Oct 2017 Social HCQ decreases CV events, DM 41% & benefits metabolic profile in RA- HCQ useful add on w/ other DMARDs @DrPetryna
09 Oct 2017 Social Annual costs assoc w/ adverse drug events in US rose from $76.6 billion 1995 to >$177.4 bill 2000; hosp 70% of total
08 Oct 2017 Social RheumNOw Wk in Review is Up! Tof lymphoma risk, early Dx of RA, Preg & biologics, 2016 top 5 Rheumatology drugs.
08 Oct 2017 Social RT @DrPetryna: Report fromHCQ decreases CV events&benefits metabolic profile in RA- HCQ useful add on w/other DMARDs @RheumNow https://t.…
06 Oct 2017 Social 2016 US Top selling drugs: Humira $13.6 billion, Enbrel $7.4 billion, Remicade $5.3 billion, Lyrica $4.4B,RTX $3.9B
05 Oct 2017 Social RheumNow has the Rules for Stopping Biologics or DMARDs in the setting of infection, esp nonserious infections.
05 Oct 2017 Social Tramadol dosing: max is 400 mg/d. For those >75 yrs, the max is 300 mg/f; those w/ CKD (<30 mL/min) 200 mg/d
03 Oct 2017 Social `07 JIA pts followed for 3 yrs on Biologics- 25% (35) had Serious/Opportunistic infx. range 10.6-14.8/100py
03 Oct 2017 Social In 19 RCTs, 6194 RA pts received tofacitinib for 19406 pt-Yrs & 19 developed lymphoma (SIR 2.62) or 1:1000 PY risk
02 Oct 2017 Social Systematic review shows Colchicine during pregnancy doesn't increase malformations or miscarriage in FMF women.
02 Oct 2017 Social RA RCT Inclusion of FM or Depression pts or pts on SSRI had 10% less ACR20 & 1/2 LDAS responses, more W/D & AE
01 Oct 2017 Social You can Search the FDA FAERS (MedWatch) for Drug specific Adverse events - Cool!
01 Oct 2017 Social RheumNow Wk in Review is up! Podcast or Watch it!!