Thursday, 16 Aug 2018

Gout/Crystal

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12 Aug 2018 Social TheRheumNow week in review is up. Gout news, M vs F back pain, best maintenance therapy in AAV. Listen on iTunes, Stitcher or SoundCloud. https://t.co/cNiV2foNpC
07 Aug 2018 News Selective Use of HLA-B*5801 Testing in Gout
07 Aug 2018 News Febuxostat (IR or XR) Effective in Gout with Renal Impairment
07 Aug 2018 Social 10 yr study of ~13k US VA gout pts who did/didnt increase allopurinol shows dose escalation seldom achieved target SUA <6.0, but was associated with increased mortality (HR 1.08; 95%CI 1.01–1.17). Escalation more a marker of severity, not T2T https://t.co/NxzhnUfU2M
02 Aug 2018 Social Olmstead county study of 429 gout patients shows that hospitalization was associated with a 10 fold increase risk of gout flares & in hosp gout flares prolonged hospitalization by avg of 1.8 days. (all highly significant) https://t.co/ICyq4RzCds
31 Jul 2018 Social Study of >100,000 UK and Taiwan pts with incident gout shows igout confers significant Tot. Joint replacement risk (14-56% higher in gout) which was not reduced by urate lowering therapy. https://t.co/AnenjnJ4ks
31 Jul 2018 Social NLRP3 inflammasome-associated diseases (Gout, RA) could be regulated by inhibitors of CMPK2, produced after engagement of Toll receptors, CMPK2 needed for synthesis of mitochondrial DNA that drives NLRP3 activity and IL-1. https://t.co/UDtPOsjSyr
25 Jul 2018 News Steroids vs. NSAIDs in Treating Acute Gout
24 Jul 2018 News Erectile Dysfunction in Gout
20 Jul 2018 Social Dr. Jas Singh reports a significant increase of age-related macular degeneration-AMD in gout pts (20.1 gout vs 11.7 /1000 Pt Yrs = HZ 1.39) based of a 5% Medicare sampling https://t.co/daIVYdXXTH
18 Jul 2018 News Immunophysiology of the Gout Attack
13 Jul 2018 Social 5 year analysis of gout descriptors from 549 articles looked at 11 basic Dz elements & 343 unique labels, most being imprecise. An acute attack was represented by 162 unique labels w/ 1/3 articles referring to this element used at least four unique labels https://t.co/KrfhL1msu4
09 Jul 2018 News Obesity, Hypertension and Diuretics Drive Gout Risk
07 Jul 2018 Social RT @jesdaile: Up to 70% of people with gout, the most common inflammatory arthritis, don't take the pills prescribed that can completely co…
26 Jun 2018 News Public Citizen Pressures FDA to Pull Febuxostat
20 Jun 2018 ACR Video Dr. Janet Pope at EULAR 2018. Is there a Gout-Cancer Connection?
20 Jun 2018 ACR Video Dr. Jack Cush at EULAR 2018 onAnakinra in Pseudogout
20 Jun 2018 ACR Video Dr. Philip Robinson at EULAR 2018 on Gout Abstracts II
19 Jun 2018 Social Using medicare claims data, Singh & Cleveland show that elderly >65 yrs gout pts have a risk of MI = 4.1 per 1000 PYs and is 2 fold higher than those without gout. https://t.co/jozY7tc40r
17 Jun 2018 ACR Video Dr. Olga Petryna EULAR 2018 - Gout and Diabetes