Monday, 09 Dec 2019


Date Typesort ascending Title Save
23 Mar 2017 Social 3 US features of GOUT: double contour sign, tophus (hyperechoic aggregates), “snowstorm” of MSU aggregates
13 Nov 2019 Social RT @EBRheum: All the NEW Clinical Practice Guidelines for GOUT! 1. Allopurinol is 1st line 2. Start ULT during flare! 3. No tx for asympt…
31 Aug 2016 Social Canadian data same as US; #RA hosp. cut in half while #Gout hospitalizations have doubled
16 Jun 2018 Social RT @DrPetryna: #eular18 @RheumNow ABST sat0357 only 51.7% of pts compliant with ULT ( allopurinol&uloric predominantly) after 1 year. The m…
05 Oct 2016 Social Systematic review of gout shows that allopurinol Rx significantly lowers systolic & diastolic BP & creatinine levels
16 Jul 2019 Social ER study from 2015-17 shows that among 456 #gout patients, 28.3%) received opioid at discharge; 80% of these were new. Average dose was 38mg morphine equivalent for a median of 8 days - more likely w/ polyarticular gout, hx diabetes & hx prior opioids
04 Nov 2017 Social RT @DrPetryna: FORTUNE1: stepwise ⬆️ of Uloric dose comparable to colchicine+Uloric in flare prevention during intro Rx…
02 Oct 2015 Social Cactus Registry of 3079 #Gout pts, more than 1/2 have obesity, HTN, Hi-Lipids. Mean entry urate = 8.7 mg/dl
07 Dec 2017 Social Systematic review of ULT discontinuation - 5 studies shows that ULT D/C has good short term outcomes (esp if SUA is low) but delayed relapse rates occcuring 1-4.5 yrs later - more in gout (36-81%), less w/ urolithiasis (15%).
06 Nov 2017 Social RT @DrRachelTate: How do you approach your hyperuricemia pts? #ACR17 @RheumNow
03 Jan 2019 Social Analysis of pegloticase clinical trial data shows that tophus resolution was achieved by 69.6% of 23 responders, 27.9% of 43 nonresponders, and 14.3% of 21 patients who received placebo. Resolution time = 9.9 mos.
27 Oct 2015 Social Study of 97 pts: Risk of anaphylaxis with 1st infusion of rasburicase is zero, but goes to 6.1% with 2nd infusion.
13 Feb 2018 Social Systematic review of DECT Scanning in Gout included 32 articles & 1502 pts. DECT takes little time and has low radiation exposure but limited availability. It showed Sensitivity & Specificity > 80%. Dx performance was better than Xray, CT, equal to US
17 May 2016 Social Gout prevalencein NIDDM is ~10%; Those w/ both likely to be elderly, men, obese, high lipids, neuropathy w/ Low GFR
31 Mar 2018 Social RT @Rheuma_suffolk: @RonanTKavanagh @psufka @Dr_BoAbrahamsen Just reading on #gout and found this gem of a paragraph about good practice in…
12 Apr 2019 Social 71-80% of primary care diagnosed gout patients meet criteria for a gout diagnosis.
13 Jul 2018 Social 5 year analysis of gout descriptors from 549 articles looked at 11 basic Dz elements & 343 unique labels, most being imprecise. An acute attack was represented by 162 unique labels w/ 1/3 articles referring to this element used at least four unique labels
13 May 2015 Social NonAlcoholic fatty liver dz signif lower w/ regular low dose ASA; but higher w/ hyperuricemia
27 Jul 2016 Social Quercetin shown to signif. reduce Uric acid, it inhibits xanthine oxidoreductase in vitro. Not studied in gout.
13 Jun 2018 Social Dr Solomons plenary session on CANTOS substudy in @risk CVD pts shows Canakinumab lowered the risk of acute gout attacks by 50-60%, lowered hsCRP but not SUA levels. #EULAR2018 @RheumNow OP0014