Tuesday, 17 Sep 2019

Gout/Crystal

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31 Aug 2017 Social RT @pg_saavedra: Acute #gout treatment algorithm by Mayo Clinics #GoutFlare #AcuteGout @RheumPearls @RheumNow @ACRheum @RheumJnl https://t.…
20 Apr 2015 Social Allopurinol reviewed at RheumaKnowledgy http://buff.ly/1FZRNhc  via @Rheumnow
26 Oct 2018 Social RT @LCalabreseDO: Pegloticase is clearly our most important agent in Pts with high uric Acid burdens - it’s Achilles heal is immunogenicity…
06 Nov 2017 Social RT @philipcrobinson: Many many gout patients who are uncontrolled in the US. Need to get them on Rx #ACR17 #168 @RheumNow https://t.co/MOY3…
27 Apr 2016 Social Erosive polyarthritis a RARE presentation of hydroxyapatite deposition Dz. More common is calcific periarthritis https://t.co/FosL2jRnN4
22 Feb 2019 Social FDAhas added a boxed warning to the label for gout drug febuxostat (Uloric) based on results of a large postmarketing safety study and AAC panel Recs. FDA concluded that there is an increased risk for death with febuxostat compared allopurinol https://t.co/v1ANA3lI0g
07 Nov 2017 Social RT @philipcrobinson: Both generic and environmental factors influence the fractional excretion of uric acid #ACR17 @RheumNow #2061 https://…
19 Jun 2018 Social Using medicare claims data, Singh & Cleveland show that elderly >65 yrs gout pts have a risk of MI = 4.1 per 1000 PYs and is 2 fold higher than those without gout. https://t.co/jozY7tc40r
14 Jun 2016 Social Tophaceous gout occurs after >10yrs & found on ear helix, fingers, toes, wrists knees, olecranon Achilles & sclera https://t.co/6BlVuEgM89
14 May 2018 Social UAB to lead the RECIPE trial in gout - a phase II trial to evaluate the utility of background mycophenolate (MMF) in patient receiving IV pegloticase injection for gout. Presumeably the MMF will block any interferring immunogenicity to PEG. https://t.co/ypBjwkeLpf
01 Dec 2016 Social @RonanTKavanagh @reinmd77 I start all new ULT (allopurinol, febuxostat) with either 5mg pred or NSAID (Never Colchicine). No flares IMHO
08 Aug 2019 Social Internet based study by Choi et al - looked at 517 gout patients and examined if gout flares were associated with vaccination. They found a twofold higher odds of gout flare (adjusted OR 1.99; 95% CI 1.01 to 3.89 in those who were vaccinated (any vaccine). https://t.co/8zLSt3YVZF
13 Jun 2018 Social Dr Solomons plenary session on CANTOS substudy in @risk CVD pts shows Canakinumab lowered the risk of acute gout attacks by 50-60%, lowered hsCRP but not SUA levels. #EULAR2018 @RheumNow OP0014 https://t.co/7eWwHKDwrn
27 Oct 2015 Social Study of 97 pts: Risk of anaphylaxis with 1st infusion of rasburicase is zero, but goes to 6.1% with 2nd infusion. https://t.co/GAnejQK2Ja
05 Oct 2016 Social Systematic review of gout shows that allopurinol Rx significantly lowers systolic & diastolic BP & creatinine levels https://t.co/F1LbrU1UUA
30 May 2017 Social British Soc.Rheumatology releases new guideline for Rx of gout; noting curative ULT must be offered to all pts early https://t.co/eda5E6V7Lp
07 Dec 2017 Social Systematic review of ULT discontinuation - 5 studies shows that ULT D/C has good short term outcomes (esp if SUA is low) but delayed relapse rates occcuring 1-4.5 yrs later - more in gout (36-81%), less w/ urolithiasis (15%). https://t.co/RTIwuH154S
12 Apr 2019 Social 71-80% of primary care diagnosed gout patients meet criteria for a gout diagnosis. https://t.co/bfmIpWiu0d
04 Nov 2017 Social RT @DrPetryna: FORTUNE1: stepwise ⬆️ of Uloric dose comparable to colchicine+Uloric in flare prevention during intro Rx https://t.co/MifSt…
13 May 2015 Social NonAlcoholic fatty liver dz signif lower w/ regular low dose ASA; but higher w/ hyperuricemia http://t.co/8tS9dAkmuA http://t.co/Jod0578pcw