Friday, 21 Feb 2020


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14 May 2018 Social UAB to lead the RECIPE trial in gout - a phase II trial to evaluate the utility of background mycophenolate (MMF) in patient receiving IV pegloticase injection for gout. Presumeably the MMF will block any interferring immunogenicity to PEG.
27 Apr 2016 Social Erosive polyarthritis a RARE presentation of hydroxyapatite deposition Dz. More common is calcific periarthritis
29 Nov 2019 Social Crossreactivity events between allopurinol rashes and febuxostat are very low
31 Aug 2017 Social RT @pg_saavedra: Acute #gout treatment algorithm by Mayo Clinics #GoutFlare #AcuteGout @RheumPearls @RheumNow @ACRheum @RheumJnl https://t.…
26 Oct 2018 Social RT @LCalabreseDO: Pegloticase is clearly our most important agent in Pts with high uric Acid burdens - it’s Achilles heal is immunogenicity…
16 Jun 2018 Social RT @DrPetryna: #eular18 @RheumNow ABST sat0357 only 51.7% of pts compliant with ULT ( allopurinol&uloric predominantly) after 1 year. The m…
14 Jun 2016 Social Tophaceous gout occurs after >10yrs & found on ear helix, fingers, toes, wrists knees, olecranon Achilles & sclera
06 Nov 2017 Social RT @philipcrobinson: Many many gout patients who are uncontrolled in the US. Need to get them on Rx #ACR17 #168 @RheumNow…
16 Jul 2019 Social ER study from 2015-17 shows that among 456 #gout patients, 28.3%) received opioid at discharge; 80% of these were new. Average dose was 38mg morphine equivalent for a median of 8 days - more likely w/ polyarticular gout, hx diabetes & hx prior opioids
27 Oct 2015 Social Study of 97 pts: Risk of anaphylaxis with 1st infusion of rasburicase is zero, but goes to 6.1% with 2nd infusion.
06 Nov 2017 Social RT @DrRachelTate: How do you approach your hyperuricemia pts? #ACR17 @RheumNow
07 Dec 2017 Social Systematic review of ULT discontinuation - 5 studies shows that ULT D/C has good short term outcomes (esp if SUA is low) but delayed relapse rates occcuring 1-4.5 yrs later - more in gout (36-81%), less w/ urolithiasis (15%).
05 Oct 2016 Social Systematic review of gout shows that allopurinol Rx significantly lowers systolic & diastolic BP & creatinine levels
13 Jul 2018 Social 5 year analysis of gout descriptors from 549 articles looked at 11 basic Dz elements & 343 unique labels, most being imprecise. An acute attack was represented by 162 unique labels w/ 1/3 articles referring to this element used at least four unique labels
13 Feb 2018 Social Systematic review of DECT Scanning in Gout included 32 articles & 1502 pts. DECT takes little time and has low radiation exposure but limited availability. It showed Sensitivity & Specificity > 80%. Dx performance was better than Xray, CT, equal to US
13 May 2015 Social NonAlcoholic fatty liver dz signif lower w/ regular low dose ASA; but higher w/ hyperuricemia
31 Mar 2018 Social RT @Rheuma_suffolk: @RonanTKavanagh @psufka @Dr_BoAbrahamsen Just reading on #gout and found this gem of a paragraph about good practice in…
12 Apr 2019 Social 71-80% of primary care diagnosed gout patients meet criteria for a gout diagnosis.
30 May 2017 Social British Soc.Rheumatology releases new guideline for Rx of gout; noting curative ULT must be offered to all pts early
13 Jun 2018 Social Dr Solomons plenary session on CANTOS substudy in @risk CVD pts shows Canakinumab lowered the risk of acute gout attacks by 50-60%, lowered hsCRP but not SUA levels. #EULAR2018 @RheumNow OP0014