Friday, 21 Feb 2020

Gout/Crystal

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14 May 2018 Social UAB to lead the RECIPE trial in gout - a phase II trial to evaluate the utility of background mycophenolate (MMF) in patient receiving IV pegloticase injection for gout. Presumeably the MMF will block any interferring immunogenicity to PEG. https://t.co/ypBjwkeLpf
27 Apr 2016 Social Erosive polyarthritis a RARE presentation of hydroxyapatite deposition Dz. More common is calcific periarthritis https://t.co/FosL2jRnN4
29 Nov 2019 Social Crossreactivity events between allopurinol rashes and febuxostat are very low https://t.co/jVVQhtB0CK
31 Aug 2017 Social RT @pg_saavedra: Acute #gout treatment algorithm by Mayo Clinics #GoutFlare #AcuteGout @RheumPearls @RheumNow @ACRheum @RheumJnl https://t.…
26 Oct 2018 Social RT @LCalabreseDO: Pegloticase is clearly our most important agent in Pts with high uric Acid burdens - it’s Achilles heal is immunogenicity…
16 Jun 2018 Social RT @DrPetryna: #eular18 @RheumNow ABST sat0357 only 51.7% of pts compliant with ULT ( allopurinol&uloric predominantly) after 1 year. The m…
14 Jun 2016 Social Tophaceous gout occurs after >10yrs & found on ear helix, fingers, toes, wrists knees, olecranon Achilles & sclera https://t.co/6BlVuEgM89
06 Nov 2017 Social RT @philipcrobinson: Many many gout patients who are uncontrolled in the US. Need to get them on Rx #ACR17 #168 @RheumNow https://t.co/MOY3…
16 Jul 2019 Social ER study from 2015-17 shows that among 456 #gout patients, 28.3%) received opioid at discharge; 80% of these were new. Average dose was 38mg morphine equivalent for a median of 8 days - more likely w/ polyarticular gout, hx diabetes & hx prior opioids https://t.co/xf2jD1i4hg
27 Oct 2015 Social Study of 97 pts: Risk of anaphylaxis with 1st infusion of rasburicase is zero, but goes to 6.1% with 2nd infusion. https://t.co/GAnejQK2Ja
06 Nov 2017 Social RT @DrRachelTate: How do you approach your hyperuricemia pts? #ACR17 @RheumNow
07 Dec 2017 Social Systematic review of ULT discontinuation - 5 studies shows that ULT D/C has good short term outcomes (esp if SUA is low) but delayed relapse rates occcuring 1-4.5 yrs later - more in gout (36-81%), less w/ urolithiasis (15%). https://t.co/RTIwuH154S
05 Oct 2016 Social Systematic review of gout shows that allopurinol Rx significantly lowers systolic & diastolic BP & creatinine levels https://t.co/F1LbrU1UUA
13 Jul 2018 Social 5 year analysis of gout descriptors from 549 articles looked at 11 basic Dz elements & 343 unique labels, most being imprecise. An acute attack was represented by 162 unique labels w/ 1/3 articles referring to this element used at least four unique labels https://t.co/KrfhL1msu4
13 Feb 2018 Social Systematic review of DECT Scanning in Gout included 32 articles & 1502 pts. DECT takes little time and has low radiation exposure but limited availability. It showed Sensitivity & Specificity > 80%. Dx performance was better than Xray, CT, equal to US https://t.co/GkbSKNP7D2
13 May 2015 Social NonAlcoholic fatty liver dz signif lower w/ regular low dose ASA; but higher w/ hyperuricemia http://t.co/8tS9dAkmuA http://t.co/Jod0578pcw
31 Mar 2018 Social RT @Rheuma_suffolk: @RonanTKavanagh @psufka @Dr_BoAbrahamsen Just reading on #gout and found this gem of a paragraph about good practice in…
12 Apr 2019 Social 71-80% of primary care diagnosed gout patients meet criteria for a gout diagnosis. https://t.co/bfmIpWiu0d
30 May 2017 Social British Soc.Rheumatology releases new guideline for Rx of gout; noting curative ULT must be offered to all pts early https://t.co/eda5E6V7Lp
13 Jun 2018 Social Dr Solomons plenary session on CANTOS substudy in @risk CVD pts shows Canakinumab lowered the risk of acute gout attacks by 50-60%, lowered hsCRP but not SUA levels. #EULAR2018 @RheumNow OP0014 https://t.co/7eWwHKDwrn