Friday, 18 Oct 2019


Date Typesort ascending Title Save
27 Oct 2015 Social Study of 97 pts: Risk of anaphylaxis with 1st infusion of rasburicase is zero, but goes to 6.1% with 2nd infusion.
30 May 2017 Social British Soc.Rheumatology releases new guideline for Rx of gout; noting curative ULT must be offered to all pts early
17 May 2016 Social Gout prevalencein NIDDM is ~10%; Those w/ both likely to be elderly, men, obese, high lipids, neuropathy w/ Low GFR
12 Apr 2019 Social 71-80% of primary care diagnosed gout patients meet criteria for a gout diagnosis.
07 Dec 2017 Social Systematic review of ULT discontinuation - 5 studies shows that ULT D/C has good short term outcomes (esp if SUA is low) but delayed relapse rates occcuring 1-4.5 yrs later - more in gout (36-81%), less w/ urolithiasis (15%).
04 Nov 2017 Social RT @DrPetryna: FORTUNE1: stepwise ⬆️ of Uloric dose comparable to colchicine+Uloric in flare prevention during intro Rx…
13 Jul 2018 Social 5 year analysis of gout descriptors from 549 articles looked at 11 basic Dz elements & 343 unique labels, most being imprecise. An acute attack was represented by 162 unique labels w/ 1/3 articles referring to this element used at least four unique labels
13 May 2015 Social NonAlcoholic fatty liver dz signif lower w/ regular low dose ASA; but higher w/ hyperuricemia
27 Jul 2016 Social Quercetin shown to signif. reduce Uric acid, it inhibits xanthine oxidoreductase in vitro. Not studied in gout.
06 Nov 2017 Social RT @KDAO2011: Gout pts more likely to achieve sUA goal< 6 mg/dL if managed by a rheumatologist. Go team Rheum! #ACR17 #166 @rheumnow https:…
02 Aug 2018 Social Olmstead county study of 429 gout patients shows that hospitalization was associated with a 10 fold increase risk of gout flares & in hosp gout flares prolonged hospitalization by avg of 1.8 days. (all highly significant)
10 Jun 2015 Social The relationship between urate, allopurinol & CV events & renal disease reviewed Am J Kid Dz
28 Aug 2016 Social Gout patients have a 17% increased risk of fractures ( limbs & spine). Interestingly allopurinol use lowers risk
07 Nov 2017 Social RT @psufka: Drink ☕️!!! Lower coffee consumption is associated with gout! #ACR17 @RheumNow #2066
28 Sep 2018 Social Horizon announces a new trial to evaluate the efficacy of MTX in prolonging efficacy and preventing anti-PEG antibodies in refractory gout patients treated with Pegloticase IV
12 Aug 2015 Social In CKD patients allopurinol adjustments may not be needed; but Colchicine must be adjusted w/ CKD- high toxicity risk
07 Aug 2019 Social PLoS reports that a study of 10,059 men from Israel were followed serially showing that higher variability in serum Uric Acid levels over 5 years was clearly predictive of 18-year Coronary heart disease and all-cause mortality.
26 Apr 2018 Social A large CV prevention trial found 722 new gout cases among 12,866 men (age 35–57). Chronic kidney dz assoc w/ a 61% incr risk of gout (HR 1.61), increased w/ proteinuria & hematuria, but not by serum urate
14 Mar 2017 Social Great review of Gout 2017 by Dr. Keenan. Gout care cost $31.8 billion from 2005-11
21 Apr 2016 Social Gout on urate lowering Rx who get attacks are: 1) noncompliant; 2) not on right dose; 3) havent reached target <6; 4) new renal dysfunction