Wednesday, 18 Sep 2019

Gout/Crystal

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12 Aug 2015 Social In CKD patients allopurinol adjustments may not be needed; but Colchicine must be adjusted w/ CKD- high toxicity risk http://t.co/ZsfwuCXxwv
26 Apr 2018 Social A large CV prevention trial found 722 new gout cases among 12,866 men (age 35–57). Chronic kidney dz assoc w/ a 61% incr risk of gout (HR 1.61), increased w/ proteinuria & hematuria, but not by serum urate https://t.co/DOUBaACaM6
07 Aug 2019 Social PLoS reports that a study of 10,059 men from Israel were followed serially showing that higher variability in serum Uric Acid levels over 5 years was clearly predictive of 18-year Coronary heart disease and all-cause mortality. https://t.co/bDqI32aVXt
16 Sep 2019 Social Review of 24 guidance papers on gouts shows agreement over T2T fo ruric acid level and long-term controlindications for urate-lowering therapy 1st line drugs acute attack. Inconsistent were the initiation of ULT & Rx of asymptomatic hyperuricemia. https://t.co/j6v2Jp8L9t
22 Sep 2016 Social Pegloticase failure linked to PEG Abs - may be improved/tolerated by concomitant Imuran - interesting case report https://t.co/9j5EaBlq3B
29 Apr 2017 Social #SOTA2017 Dr. Gabriel In RA hyperuricemia is predictived of PAD and CV Events
27 Nov 2017 Social Gout risk assoc w/ Soda & high fructose corn syrup. New NHANES study shows 1209 young adults, 20–30 yrs enrolled 20… https://t.co/Z8qvW3FgAE
22 Mar 2019 Social Prevalence of gout continues to rise. NHANES data say prevalence of gout is 9.2 million inUS adults (2015-2016) (5.9 mill men; 3.3 mil women); hyperuricemia prevalences is 20.0%. ULT use in gout was 33% between 2007-2014. https://t.co/nDEJM7gTGA
27 Oct 2017 Social Metanalysis of ULT adherence in Gout, 16 studies show adherence 46-48%, higher w/age, DM, HTN comorbidityhttps://buff.ly/2y6kOQd
04 May 2015 Social Erectile dsyfunction in #Gout. Even after adjustments for age, hypertension, diabetes, and obesity. http://buff.ly/1cbFZkH 
09 Mar 2016 Social 7 yr old data shows #Colchicine misuse with no dose adjustments for renal insufficency during acute gout in France https://t.co/JXMd1tq47s
09 Feb 2018 Social RT @uptoTate: Pegloticase weekly for the 1st three weeks may be a better regimen for sustained low uric acid levels (vs every other week).…
28 Dec 2018 Social Despite many excellent therapies, most patients with gout are not adequately managed, and patients and providers have many misconceptions about gout. Great review by Ted Fields, MD https://t.co/Njpo1225XP
04 Jun 2019 Social UK Clinical Practice Database matched 62,234 pts with and without gout showing more venous thromboembolic events in gout (0.373 vs 0.27 per 100 Pt-yrs) (aHR 1.25, 95% CI 1.15–1.35) - not affected by ULT & not significant while in hospital (aHR 1.01) https://t.co/XrInEwckez
06 Nov 2017 Social RT @Janetbirdope: #GAMECHANGER uncontrolled gout is associated with more heart failure so treat gout effectively. #acr17 @rheumnow #1119 ht…
29 Jun 2015 Social Costs of #Gout related to # flares. Claims data 102703 gout pts: 87% had 0-1 flares/yr; 9.4% 2 flares, 3.7% 3+ flares http://t.co/rTWHLIhqWE
10 May 2016 Social Survey of PCPs & house officers show disparate practices in gout Dx & Rx - esp w/ colchicine, ULT use & monitoring https://t.co/X50G1bkP0Q
29 Mar 2018 Social Why would anyone treat gout with colchicine when steroids & NSAIDs are fast, dirt cheap, more practical & safer than colchicine? Colchicine has given us thousands of years of GI distress & diarrhea now at a ridiculously high cost!
04 Jul 2019 Social RT @RheumNow: Comparison of high and low iris acid levels in a large cohort of gout patients shows high SUA associated with more comorbidit…
23 Sep 2015 Social High consumption of sugar-sweetened beverages causes higher serum urate levels, but only in those with high BMI http://t.co/yHJSKrx3gl