Friday, 06 Dec 2019

Gout/Crystal

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13 Mar 2017 Social In 2002, there was 3.9 million outpatient visits for #Gout - only 1.3% were to rheumatologists. https://t.co/r5PRddtNfY
18 Dec 2017 Social Check out Dr. Ken Saags #ACR17 video on the Triple study - how a tolerizing dose of pegloticase makes it safer and more tolerable! https://t.co/YwJtO2LVp7
31 Jul 2019 Social Observational study of 124 gouty patients with high cholesterol & triglycerides treated with ULT (febuxostat, allopurinol, benzbromarone) showed that ULT significantly lowered SUA and lipid levels too. https://t.co/JSdh3TRTX3
25 Jan 2019 Social Using the 1998-2014 U.S. National Inpatient Sample- gout was associated with 9-20% higher healthcare utilization and 6% higher hazard of transfusion after primary hip replacement surgery. https://t.co/cSFnVJiX8s
01 Aug 2015 Social 81 arthritis pts (1/2 w/ gout) were studied w/ DECT scans. DECT had sensitivity of 90% and specificity of 83%. http://t.co/fL6t7zFPmY
24 Jul 2017 Social Discrepancy between ultrasound and DECT quantification of urate tophi in gout joints; lower sensitivity w/ DECT https://t.co/RL5Vkq6GSz
23 Feb 2018 Social Gout management by UK Rheums conform to guidelines, yet ~45% reach target SUA<6.0. Study of 4343 Gout pts; 82% M; 13% crystal-proven. 29% stopped diuretic, 76% on ULT; prophylaxis was co-prescribed for 94%. https://t.co/G2HDF0wO2h
21 Nov 2019 Social The draft 2020 ACR #gout guidelines were presented at the last slot of the meeting. Big changes for ULT initiation #ACR19 @philipcrobinson [Slides attached] https://t.co/4g3YUlm7Sa
07 Oct 2015 Social The price of generics more than doubled in 1/7 generics. Colchicine price rose 2000% w/ FDA new safety policies. http://t.co/wcFKfBAYz6
26 Aug 2016 Social Gout patients have a 17% increased risk of fractures ( limbs & spine). Interestingly allopurinol use lowers risk https://t.co/LwXQyZ1VcO
05 Nov 2017 Social RT @_connectedcare: DASH diet lowering urate in specific subgroups #ACR17 @rheumnow https://t.co/boEc3UKsny
17 Apr 2018 Social Using the 2012 ACR gout guidelines, an ACR working group developed new quality measures for gout: 1) evaluating indications for ULT; 2) monitoring serum urate; 3)treat-to-target outcome. But only 32%-58% of pts achieve these; thus room for improvement! https://t.co/6YGFRktVMS
31 Jul 2018 Social NLRP3 inflammasome-associated diseases (Gout, RA) could be regulated by inhibitors of CMPK2, produced after engagement of Toll receptors, CMPK2 needed for synthesis of mitochondrial DNA that drives NLRP3 activity and IL-1. https://t.co/UDtPOsjSyr
25 Nov 2015 Social Danish population study shows 7127 people on allopurinol have 11% less CV mortality and 32% all cause mortality https://t.co/rbtXku8QYA
25 Oct 2016 Social Rheumatoid nodules almost never ulcerate; but gout tophi DO! Risk factors age, tophus size & no protective sensation https://t.co/kmsnNlRBF2
16 Jun 2018 Social RT @Janetbirdope: A sore toe can kill you! Danish population study excluded past cancers and found pts with goit had mor cancer. Lymphoma c…
16 Sep 2018 Social 10 yr study - 581 gout vs 598 OA pts shows gout with a lower risk of colorectal cancer (0.8% vs 3.7%). https://t.co/xPbj1iEGDs Other studies have shown increased overall Cancer risk in gout https://t.co/RDaDhm5V31
23 Feb 2016 Social Astra-Zeneca's new gout drug, lesinurad (Zurampic) gets EU approval for gout. https://t.co/ZCJRA1bPHH
11 Jan 2017 Social FDA reviewing NDA for new combo drug: allopurinol + lesinurad (Ironwood Pharm) to Rx hyperuricemia uncontrolled gout https://t.co/e95R8TlXuv
08 Nov 2017 Social RT @philipcrobinson: I think that is a simplistic view, skills, knowledge and unknowns probably play a role in my view #ACR17 @RheumNow htt…