Tuesday, 22 Oct 2019

Gout/Crystal

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05 Nov 2017 Social RT @_connectedcare: DASH diet lowering urate in specific subgroups #ACR17 @rheumnow https://t.co/boEc3UKsny
22 Oct 2015 Social Gouty arthritis requiring allopurinol is associated with an excess risk of major fractures and hip Fx, moreso in men https://t.co/Uap8lHE07G
08 Nov 2017 Social RT @philipcrobinson: I think that is a simplistic view, skills, knowledge and unknowns probably play a role in my view #ACR17 @RheumNow htt…
06 Nov 2017 Social RT @philipcrobinson: Patients with gout have their XOI stopped when they present with AKI. Evidence free zone and makes gout Rx harder #111…
31 May 2019 Social Korean National Health Insurance data compared the risk of CV events in 39,640 gout pts starting allopurinol or febuxostat. MACE incidence was 1.89 vs 1.84/100PY (HR 1.09; 0.90, 1.32) Thus, no significant difference in CV risk with these agents in Asians https://t.co/l316siAqd8
25 Feb 2019 Social QD Clinic - New Changes to Gout Guidelines. Lessons from the clinic - a noncompliant gout patient needs to restart his gout drugs, what to do with febuxostat? https://t.co/XwaUewBjWS via @YouTube
30 Jun 2016 Social Pharmacist lead virtual monitoring of uric acid levels leads to 3 fold more success in achieving SUA<6.0 https://t.co/DJBhGbLSL9
10 Jan 2018 Social Krystexxa annual sales expected to increase from $400 million to $750 million. Horizon reports the number of gout pts treated increased from 50,000 to 100,000. https://t.co/sPTf8UueVc
07 Nov 2017 Social RT @philipcrobinson: Nice data on cumulative incidence of gout by serum urate #ACR17 @RheumNow https://t.co/HsDPGKLp2e
29 Apr 2015 Social MRI study of Gout & RA: synovitis in both. Gout had less cartilage damage (CD), but BM edema & CD strongest in RA http://buff.ly/1PFXVSL 
19 Sep 2016 Social DECT imaging studies in gout patients shows that Erosions occur from the outside in (not inside out as in RA). https://t.co/WzHfjYIXQv
11 Jan 2017 Social FDA reviewing NDA for new combo drug: allopurinol + lesinurad (Ironwood Pharm) to Rx hyperuricemia uncontrolled gout https://t.co/e95R8TlXuv
20 Aug 2018 Social A study of 27,959 acute coronary syndrome patients shows that the 46% with hyperuricemia (SUA > 6.0) had significantly greaters risks of cardiovascular events, regardless of a diagnosis of gout. https://t.co/chEJ8QeFh0
26 Mar 2018 Social UK gen population database shows that statin use in #gout patients was associated with a 16% lower risk of all-cause mortality (HR=0.84) & 7.7 fewer deaths per 1,000 PY; moreso in those without prior CV disease https://t.co/ZFpvSelo4d
16 Jun 2015 Social 113 hyperuricemia pts randomized to PBO v allopurinol. Allopurinol had less CKD progression & less CV events(HR 0.43) http://t.co/wgKs7wWFeA
22 Nov 2016 Social CLEAR 2 Lesinurad (Zurampic) 200 or 400 mg added to allopurinol; 55-66% got to SUA <6. But 5-15% renal side effects https://t.co/rzVoDevT5J
19 Apr 2017 Social Acute Arthritis US sensitivity/specificity=double contour 42/92%, IA aggregates 58/92%, tophi 40/100. w/ PPV 88-100% https://t.co/pf2T3JBAeU
30 May 2018 Social RT @philipcrobinson: Really interesting ‘Sons of Gout’ study shows asymptomatic crystals present. Is the threshold different? https://t.co/…
23 Feb 2016 Social Astra-Zeneca's new gout drug, lesinurad (Zurampic) gets EU approval for gout. https://t.co/ZCJRA1bPHH
10 Sep 2015 Social Wearable mouth guard capable of tracking uric acid levels! Is this the future of gout? http://t.co/qjbJN5jaJa