Wednesday, 11 Dec 2019


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20 Aug 2019 Social 87 #Gout patients treated with ULT and followed with serial Xrays and DECT scanning shows that lowering uric acid in a T2T strategy did not change xray over 2 years, but did show significantly less urate erosions by DECT.
14 Aug 2019 Social Cross sectional analysis of ~3000 and meta-analysis (14 studies) finds #gout has a higher risk of hypothyroidism, esp in female gout pts (OR=2.44;1.15-5.17); Metaanalysis ^risk hypothyroidism in gout (OR=1.51) and hyperuricemic pts (OR=1.34)
08 Aug 2019 Social Internet based study by Choi et al - looked at 517 gout patients and examined if gout flares were associated with vaccination. They found a twofold higher odds of gout flare (adjusted OR 1.99; 95% CI 1.01 to 3.89 in those who were vaccinated (any vaccine).
07 Aug 2019 Social Prospective study of 83 gout patients; 77 on urate lowering Rx, 6 discontinued Rx. The D/C group had no change in MSU deposits or SUA levels, In the ULT group MSU burden significantly decreased (MSU volume: p=0.007) and sUA dropped from 7.2 to 5,8 mg/dl.
07 Aug 2019 Social PLoS reports that a study of 10,059 men from Israel were followed serially showing that higher variability in serum Uric Acid levels over 5 years was clearly predictive of 18-year Coronary heart disease and all-cause mortality.
02 Aug 2019 Social 70 #gout pts studied & 44.3% developed post-surgical flares. Risk factors included Presurgical sUA ≥ 9 mg/dL (OR 3.77) & sUA changes before and after surgery (OR 1.62); but \allopurinol reduced risk (OR 0.15). Mean time to flare=3.7 days. Knee > MTP1
31 Jul 2019 Social Observational study of 124 gouty patients with high cholesterol & triglycerides treated with ULT (febuxostat, allopurinol, benzbromarone) showed that ULT significantly lowered SUA and lipid levels too.
31 Jul 2019 Social NHANES analysis shows that higher serum uric acid (SUA) levels had a greater risk of coronary heart disease and stroke mortality (mainly women >50 years); but there was no link between SUA and all-cause and cancer mortality.
26 Jul 2019 Social FDA has approved generic febuxostat 40 mg & 80 mg tabs, for gout - to be made by Read more at Business Medical Dialogues: Alembic Pharma gets USFDA nod for generic version of Uloric tablets
21 Jul 2019 Social The RheumNow Podcast is up! Discussions on MDA-5 Abs & DM; gout & narcotics; IA capsaicin in OA; and ADA vs UPA. Watch here>> or listen on iTunes or SoundCloud>>
19 Jul 2019 Social Mayo study comparing 429 Gout patients in 1990 and 2010 shows less 1st time Podagra 74% to 59% (p<0.001) and 24% higher flare rates in 2010. Predictors of future flares were hyperuricemia (HR 1.59) and CKD (HR 1.34)
16 Jul 2019 Social ER study from 2015-17 shows that among 456 #gout patients, 28.3%) received opioid at discharge; 80% of these were new. Average dose was 38mg morphine equivalent for a median of 8 days - more likely w/ polyarticular gout, hx diabetes & hx prior opioids
08 Jul 2019 News Opioids Overused in Acute Gout
04 Jul 2019 Social RT @RheumNow: Comparison of high and low iris acid levels in a large cohort of gout patients shows high SUA associated with more comorbidit…
03 Jul 2019 Social RT @GoutGroup: #Hyperuricemia (HUC) /#gout found to be associated with CVD in a cohort of 37,315 PsA patients. Investigators at Icahn Mt S…
03 Jul 2019 News Allopurinol Fails to Curtail Hypertension
03 Jul 2019 Social RT @RheumNow: Dr. Peter Lipsky - 1 Million #Gout Patients & who cares for them. SAT0435 #EULAR2018
02 Jul 2019 Social Men with #gout are severely under treated, under educated and unmotivated to better manage their gout!
21 Jun 2019 ACR Video Brian Lamoreaux on higher comorbidities in Gout
21 Jun 2019 ACR Video Dr. Peter Lipsky - 1 Million #Gout Patients & who cares for them