Friday, 18 Oct 2019

Gout/Crystal

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02 Aug 2019 Social 70 #gout pts studied & 44.3% developed post-surgical flares. Risk factors included Presurgical sUA ≥ 9 mg/dL (OR 3.77) & sUA changes before and after surgery (OR 1.62); but \allopurinol reduced risk (OR 0.15). Mean time to flare=3.7 days. Knee > MTP1 https://t.co/U6rl5c8Cf3
03 Aug 2015 Social 81 arthritis pts (1/2 w/ gout) were studied w/ DECT scans. DECT had sensitivity of 90% and specificity of 83%. http://t.co/T3Izfk0WjU
21 Dec 2017 Social Olmstead Co (Mayo) study shows rising incidence of gout (67-->137/100000) from 1989 to 2010 is associated w/ rising rates of comorbidity (HTN 54->69%; DM 6-25%; CKD 11-28%; morbid obesity 10-29%) https://t.co/LsVYIa1rH5
31 Jul 2018 Social Study of >100,000 UK and Taiwan pts with incident gout shows igout confers significant Tot. Joint replacement risk (14-56% higher in gout) which was not reduced by urate lowering therapy. https://t.co/AnenjnJ4ks
20 Apr 2016 Social NU-FLASH RCT 141 cardiac surgery pts w/ CKD+hyperuricemia Rx w/ Uloric vs Allopurinol. Uloric had lower SUA, CRP https://t.co/1Jt6u85tCv
08 Oct 2015 Social Crystal ID from 1593 SF finds MSU in 83% gout, 10% PsA, 2.8% OA, 0% RA or SpA. CPPD in 86% pseudogout, 19% RA,14% OA http://t.co/298bYOdlXv
11 Aug 2017 Social RT @emartinmola: For acute gout, corticosteroids look safer than NSAIDs https://t.co/yo3AV66waX
23 Oct 2015 Social FDA Arthritis Advisory Committee votes 10-4 in favor of Lesinurad (+XOI) for hyperuricemia/gout; despite safety concerns over renal effects
20 Oct 2017 Social Review of 10 wt loss intervention trials in obese or overweight gout pts - 6/8 showed Wt loss reduces attacks. https://t.co/pfEAoWwdIR
04 Jul 2016 Social RT @MarkHankins1: @RheumNow and ask yourself, "Am I part of the disease or of the cure?" - Coldplay
03 Feb 2016 Social Methotrexate had no benefit in a small crossover trial in pts w/ chronic Calcium Pyrophosphate Deposition Disease https://t.co/MZwe8DmAPK
06 Nov 2017 Social RT @KDAO2011: Dr D Solomon #ACR17 @rheumnow YR in Review DASH diet (see photo) decrease gout risk https://t.co/rNWszhrAD9 https://t.co/PKCP…
21 Sep 2016 Social Nurses Health Study shows women w/ gout have 38% increased risk hip fractures. https://t.co/MxZeMA5Tho
01 May 2015 Social Prednisone safe for symptomatic hyperuricaemic patients with Cardiac Failure & Hypertension Editorial #rheumedu http://www.jrheum.org/content/42/5/739.full …
03 Jul 2019 Social RT @GoutGroup: #Hyperuricemia (HUC) /#gout found to be associated with CVD in a cohort of 37,315 PsA patients. Investigators at Icahn Mt S…
07 Nov 2017 Social RT @philipcrobinson: Kaplan-Meier curve; not for death… but for developing gout by serum urate concentration #ACR17 @RheumNow https://t.co/…
28 Feb 2019 Social FDA approval of an oral colchicine Gloperba for Adult Gout Flares - is this really an advance? At what price? You dont need colchicine to manage most cases of gout -my opinion of course! https://t.co/YnPl4Qchjj
29 Nov 2016 Social In the USA, #Gout rose from 4.7 million in 1994 to 8.1 mill in 2010 and is related to obesity epidemic. https://t.co/OMqe2mRB7l
17 Jun 2015 Social SUGAR study:Classic #Gout- jt red,difficulty walking,max pain <24 hrs,duration<2 wks, tophus,MTP1,SUA>6,Xray erosion http://t.co/bSoP5t3LhL
11 Sep 2019 Social UK Clinical Practice Database compared 68,897 gout pts vs 554,964 without gout, showing gout doubles risk of (8.5/1000PY vs 4.1/1000PY w/o gout). Risk highest with ESRD. Gout did not increase CKD related deaths. https://t.co/oHpxa3ybVK