Friday, 10 Apr 2020


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01 May 2016 Social Goofiest study of the month: Pricking blood and moxibustion effective in treating gout in China.
29 Apr 2015 Social MRI study of Gout & RA: synovitis in both. Gout had less cartilage damage (CD), but BM edema & CD strongest in RA 
11 Jan 2017 Social FDA reviewing NDA for new combo drug: allopurinol + lesinurad (Ironwood Pharm) to Rx hyperuricemia uncontrolled gout
08 Nov 2017 Social RT @philipcrobinson: I think that is a simplistic view, skills, knowledge and unknowns probably play a role in my view #ACR17 @RheumNow htt…
30 Jun 2016 Social Pharmacist lead virtual monitoring of uric acid levels leads to 3 fold more success in achieving SUA<6.0
16 Jun 2015 Social 113 hyperuricemia pts randomized to PBO v allopurinol. Allopurinol had less CKD progression & less CV events(HR 0.43)
13 Nov 2019 Social RT @Janetbirdope: Gout guidelines Allopurinol over febuxostat, dose low &slowly increase, T2T for serum Uric acid. Only Febuxostat if allop…
19 Apr 2017 Social Acute Arthritis US sensitivity/specificity=double contour 42/92%, IA aggregates 58/92%, tophi 40/100. w/ PPV 88-100%
10 Jan 2018 Social Krystexxa annual sales expected to increase from $400 million to $750 million. Horizon reports the number of gout pts treated increased from 50,000 to 100,000.
20 Aug 2018 Social A study of 27,959 acute coronary syndrome patients shows that the 46% with hyperuricemia (SUA > 6.0) had significantly greaters risks of cardiovascular events, regardless of a diagnosis of gout.
14 Mar 2019 Social QD44 - RA and Gout via @YouTube
13 Nov 2019 Social RT @DrKanikaMonga: 2020 Gout Clinical Practice Guideline ❕Regardless of disease activity, conditionally recommend - limit alcohol intake -…
26 Apr 2019 Social Comparing nearly 230,000 Taiwanese with and without gout shows gout pts have more psoriasis (1.6% vs 1.1%; adjusted OR 1.30; 1.20-1.42) and psoriatic arthritis (0.3% v 0.1%; aOR 2.50; 1.95-3.22).
18 Oct 2016 Social Cool MRI/Xrays, CPPD of Cervical spine - 85yoWM w/ neck pain, C2,4 erosions, calcification ant longitudinal ligament
04 Oct 2015 Social Pyrazinamide & ethambutol cause hyperuricemia (incr~5mg/dl) w/ impaired urate renal excretion, but no effx on Creat
05 Nov 2017 Social RT @DrRachelTate: US of MTP1, dist patellar/triceps tendons, talar + femoral cartilage for MSU in poss. gout #ACR17 @RheumNow #249 https://…
01 Apr 2018 Social UK gen population database shows that statin use in #gout patients was associated with a 16% lower risk of all-cause mortality (HR=0.84) & 7.7 fewer deaths per 1,000 PY; moreso in those without prior CV disease
23 Oct 2018 Social RT @CCalabreseDO: allopurinol prescribing habits differ between rheumatologists and nephrologists. check out abstract #2228 @RheumNow #ACR18
18 Jun 2019 Social RT @GoutGroup: A study examined whether EGCG suppresses the activation of the NLRP3 inflammasome, thereby effectively preventing gouty #inf…
01 Jan 2020 Social Can Febuxostat be given to Allopurinol Hypersensitivity? Such pts not included in registrations trials; yet many literature reports of no toxicity & rare cross-Rxn; PI says ULORIC indicated w/ intolerance to allopurinol or when allopurinol Tx not advisable