Thursday, 20 Feb 2020


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10 Oct 2018 Social CONTACT (Colchicine or Naproxen TX for Acute Gout) presented at the British Society of Rheum Mtg - 399 OL study finds equivalent responses betw Nap & Col, but trends favoring naproxen for lower early pain scores, side effects, less rescue pain meds
23 Mar 2017 Social 3 US features of GOUT: double contour sign, tophus (hyperechoic aggregates), “snowstorm” of MSU aggregates
14 Jun 2016 Social Tophaceous gout occurs after >10yrs & found on ear helix, fingers, toes, wrists knees, olecranon Achilles & sclera
29 Nov 2019 Social Crossreactivity events between allopurinol rashes and febuxostat are very low
26 Oct 2018 Social RT @LCalabreseDO: Pegloticase is clearly our most important agent in Pts with high uric Acid burdens - it’s Achilles heal is immunogenicity…
14 May 2018 Social UAB to lead the RECIPE trial in gout - a phase II trial to evaluate the utility of background mycophenolate (MMF) in patient receiving IV pegloticase injection for gout. Presumeably the MMF will block any interferring immunogenicity to PEG.
31 Aug 2017 Social RT @pg_saavedra: Acute #gout treatment algorithm by Mayo Clinics #GoutFlare #AcuteGout @RheumPearls @RheumNow @ACRheum @RheumJnl https://t.…
31 Aug 2016 Social Canadian data same as US; #RA hosp. cut in half while #Gout hospitalizations have doubled
13 Jun 2018 Social Dr Solomons plenary session on CANTOS substudy in @risk CVD pts shows Canakinumab lowered the risk of acute gout attacks by 50-60%, lowered hsCRP but not SUA levels. #EULAR2018 @RheumNow OP0014
04 Nov 2017 Social RT @DrPetryna: FORTUNE1: stepwise ⬆️ of Uloric dose comparable to colchicine+Uloric in flare prevention during intro Rx…
05 Oct 2016 Social Systematic review of gout shows that allopurinol Rx significantly lowers systolic & diastolic BP & creatinine levels
16 Jul 2019 Social ER study from 2015-17 shows that among 456 #gout patients, 28.3%) received opioid at discharge; 80% of these were new. Average dose was 38mg morphine equivalent for a median of 8 days - more likely w/ polyarticular gout, hx diabetes & hx prior opioids
13 May 2015 Social NonAlcoholic fatty liver dz signif lower w/ regular low dose ASA; but higher w/ hyperuricemia
06 Nov 2017 Social RT @DrRachelTate: How do you approach your hyperuricemia pts? #ACR17 @RheumNow
13 Jul 2018 Social 5 year analysis of gout descriptors from 549 articles looked at 11 basic Dz elements & 343 unique labels, most being imprecise. An acute attack was represented by 162 unique labels w/ 1/3 articles referring to this element used at least four unique labels
07 Dec 2017 Social Systematic review of ULT discontinuation - 5 studies shows that ULT D/C has good short term outcomes (esp if SUA is low) but delayed relapse rates occcuring 1-4.5 yrs later - more in gout (36-81%), less w/ urolithiasis (15%).
02 Oct 2015 Social Cactus Registry of 3079 #Gout pts, more than 1/2 have obesity, HTN, Hi-Lipids. Mean entry urate = 8.7 mg/dl
13 Feb 2018 Social Systematic review of DECT Scanning in Gout included 32 articles & 1502 pts. DECT takes little time and has low radiation exposure but limited availability. It showed Sensitivity & Specificity > 80%. Dx performance was better than Xray, CT, equal to US
17 May 2016 Social Gout prevalencein NIDDM is ~10%; Those w/ both likely to be elderly, men, obese, high lipids, neuropathy w/ Low GFR
12 Apr 2019 Social 71-80% of primary care diagnosed gout patients meet criteria for a gout diagnosis.