Thursday, 20 Feb 2020

Gout/Crystal

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10 Oct 2018 Social CONTACT (Colchicine or Naproxen TX for Acute Gout) presented at the British Society of Rheum Mtg - 399 OL study finds equivalent responses betw Nap & Col, but trends favoring naproxen for lower early pain scores, side effects, less rescue pain meds https://t.co/MPgRNZo42b
23 Mar 2017 Social 3 US features of GOUT: double contour sign, tophus (hyperechoic aggregates), “snowstorm” of MSU aggregates https://t.co/ragnHxBTRW
14 Jun 2016 Social Tophaceous gout occurs after >10yrs & found on ear helix, fingers, toes, wrists knees, olecranon Achilles & sclera https://t.co/6BlVuEgM89
29 Nov 2019 Social Crossreactivity events between allopurinol rashes and febuxostat are very low https://t.co/jVVQhtB0CK
26 Oct 2018 Social RT @LCalabreseDO: Pegloticase is clearly our most important agent in Pts with high uric Acid burdens - it’s Achilles heal is immunogenicity…
14 May 2018 Social UAB to lead the RECIPE trial in gout - a phase II trial to evaluate the utility of background mycophenolate (MMF) in patient receiving IV pegloticase injection for gout. Presumeably the MMF will block any interferring immunogenicity to PEG. https://t.co/ypBjwkeLpf
31 Aug 2017 Social RT @pg_saavedra: Acute #gout treatment algorithm by Mayo Clinics #GoutFlare #AcuteGout @RheumPearls @RheumNow @ACRheum @RheumJnl https://t.…
31 Aug 2016 Social Canadian data same as US; #RA hosp. cut in half while #Gout hospitalizations have doubled https://t.co/qVnEAvN538 https://t.co/KFOpKxEPd3
13 Jun 2018 Social Dr Solomons plenary session on CANTOS substudy in @risk CVD pts shows Canakinumab lowered the risk of acute gout attacks by 50-60%, lowered hsCRP but not SUA levels. #EULAR2018 @RheumNow OP0014 https://t.co/7eWwHKDwrn
04 Nov 2017 Social RT @DrPetryna: FORTUNE1: stepwise ⬆️ of Uloric dose comparable to colchicine+Uloric in flare prevention during intro Rx https://t.co/MifSt…
05 Oct 2016 Social Systematic review of gout shows that allopurinol Rx significantly lowers systolic & diastolic BP & creatinine levels https://t.co/F1LbrU1UUA
16 Jul 2019 Social ER study from 2015-17 shows that among 456 #gout patients, 28.3%) received opioid at discharge; 80% of these were new. Average dose was 38mg morphine equivalent for a median of 8 days - more likely w/ polyarticular gout, hx diabetes & hx prior opioids https://t.co/xf2jD1i4hg
13 May 2015 Social NonAlcoholic fatty liver dz signif lower w/ regular low dose ASA; but higher w/ hyperuricemia http://t.co/8tS9dAkmuA http://t.co/Jod0578pcw
06 Nov 2017 Social RT @DrRachelTate: How do you approach your hyperuricemia pts? #ACR17 @RheumNow
13 Jul 2018 Social 5 year analysis of gout descriptors from 549 articles looked at 11 basic Dz elements & 343 unique labels, most being imprecise. An acute attack was represented by 162 unique labels w/ 1/3 articles referring to this element used at least four unique labels https://t.co/KrfhL1msu4
07 Dec 2017 Social Systematic review of ULT discontinuation - 5 studies shows that ULT D/C has good short term outcomes (esp if SUA is low) but delayed relapse rates occcuring 1-4.5 yrs later - more in gout (36-81%), less w/ urolithiasis (15%). https://t.co/RTIwuH154S
02 Oct 2015 Social Cactus Registry of 3079 #Gout pts, more than 1/2 have obesity, HTN, Hi-Lipids. Mean entry urate = 8.7 mg/dl http://t.co/XVx11sqIG5
13 Feb 2018 Social Systematic review of DECT Scanning in Gout included 32 articles & 1502 pts. DECT takes little time and has low radiation exposure but limited availability. It showed Sensitivity & Specificity > 80%. Dx performance was better than Xray, CT, equal to US https://t.co/GkbSKNP7D2
17 May 2016 Social Gout prevalencein NIDDM is ~10%; Those w/ both likely to be elderly, men, obese, high lipids, neuropathy w/ Low GFR https://t.co/FWnneUXn11
12 Apr 2019 Social 71-80% of primary care diagnosed gout patients meet criteria for a gout diagnosis. https://t.co/bfmIpWiu0d