Friday, 10 Apr 2020

Gout/Crystal

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08 Nov 2017 Social RT @WShergy: Low Uric acid may raise the risk of dementia. acr2017 @rheumnow#2080 https://t.co/bBL1mG0Ga7
07 Aug 2019 Social Prospective study of 83 gout patients; 77 on urate lowering Rx, 6 discontinued Rx. The D/C group had no change in MSU deposits or SUA levels, In the ULT group MSU burden significantly decreased (MSU volume: p=0.007) and sUA dropped from 7.2 to 5,8 mg/dl. https://t.co/YfXjTKz1va
04 Feb 2016 Social Uricosuric effects are seen with Losartan, Irbesartan, CCB (amlodipine), fenofibrate, vitamin C, coffee, skim milk, yogurt and leflunomide
15 Mar 2017 Social Xrays & DECT in 92 gout pts, tophi and urate assoc w/ 80% of all erosions. Urate, tophus volume predict erosions https://t.co/JlDle82bUx
10 Jun 2015 Social Efficacy of Anakinra in Crystal synovitis. Complete improvement is seen in 3-5 days http://t.co/oTmnycx9m1
13 Nov 2019 Social RT @DrKanikaMonga: 2020 Gout Clinical Practice Guideline 42 recommendations (16 strong) - 27 ULT management (13 strong) - 5 Gout Flares (3…
07 Aug 2018 Social 10 yr study of ~13k US VA gout pts who did/didnt increase allopurinol shows dose escalation seldom achieved target SUA <6.0, but was associated with increased mortality (HR 1.08; 95%CI 1.01–1.17). Escalation more a marker of severity, not T2T https://t.co/NxzhnUfU2M
26 Apr 2016 Social Astra-Zeneca sells the rights to sell gout drug Zurampic (lesinurad) to Ironwood pharmaceutical for $265 million. https://t.co/GXht3lje3s
04 Mar 2018 Social RheumNow Wk in Review is up. Cool stuff on FDG PET in Lg Vessel vasculitis, gout Rx, nutraceuticals in OA. Listen here ht tps://buff.ly/2FhsZZH or watch it on website https://t.co/OZ1nGhCrSP
17 Aug 2015 Social Salivery uric acid levels measureable in gout - more proof that gout is a systemic uric acid deposition disease http://t.co/cA03VMuG39
29 Nov 2019 Social New package labeling says febuxostat should only be considered after allopurinol has been tried or is contraindicated. https://t.co/Sk2MhEiOhv
11 Jun 2016 Social 1,280 gout compared to 1,231 OA pts; gout had more CVD risk factors, hypertension, ^lipids, CKD but not more MI. https://t.co/zP2SK3tfeM
06 Nov 2017 Social RT @KDAO2011: Risk for CV events lower in new start probenecid (rather than allopurinol) for older >65 yo pts #ACR17 @rheumnow #159 https:/…
16 May 2019 Social Medicare analysis shows Gout patients are twice as likely to have chronic pain (HR 2.02; 95% CI 1.98-2.05) and use of allopurinol or febuxostat was associated with a lower risk of chronic pain (HR 0.72-0.79) https://t.co/xW5rVPyC69
06 Jun 2019 Social The overall prevalence of gout among US adults is 3.9%, affecting 9.2 million people. Hyperuricaemia prevalence is 14.6% - affecting 32.5 million in the US. Data from NHANES NHANES 2015–16 https://t.co/3g05GmUDUA
26 Oct 2015 Social 75 pts >50 yrs w knee effusions were studied:Ultrasound was more sensitive(60 v 40%) & specific (97 v 83%) than Xray https://t.co/dKr2BbZphN
14 Mar 2020 Social Dr Nicola Dalbeth #RNL2020 notes there are no RCTs regarding dietary manager of #gout
22 Sep 2016 Social #Gout & anti-HTN meds: diuretics, ꞵ-blockers, α-1 blockers signif increase uric acid levels. No effect w/ CCB, ACEI https://t.co/LnUTfz3zab
02 Feb 2017 Social Risk of incident gout 70 fold higher w/ SUA >10; Risk of recurrent gout is 5 fold higher if SUA >9; https://t.co/GznuJ8tq1l
09 May 2015 Social Review of Losartan shows its uricosuric, can lower Uric acid ~1.6 mg/dl & may be useful in HTN w/ hyperuricemia http://t.co/0zVqsvQIcO