Friday, 10 Apr 2020

Gout/Crystal

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06 Feb 2020 Social Analysis of 30 synovial fluid samples (12 MSU, 18 CPPD); Gout crystals were ID at room temp (92%) & refrigerated (100%) for 7 days; CPPD crystals were less durable at room temperature (67%) after 7d; w/ less reduction when refrigerated in heparin tubes. https://t.co/H2zbjp1ONg
07 Nov 2017 Social RT @KDAO2011: Prior allopurinol use may reduce risk for NSAID induce acute kidney injury in gout pts #141 #ACR17 @rheumnow https://t.co/HTA…
16 Jun 2018 Social Abstract Sat 0356 showed pegloticase results in rapid resolution of tophus in bio chemical responders but is not influenced by age gender, race, BMI, tophus location. #EULAR https://t.co/rUWEHEA2fZ
13 Feb 2019 Social Genetic study using Mendelian randomization methods in a large UK biobank shows that whereas serum Uric acid has no association with eGFR level nor CKD risk, sUA does show a significant risk of #Gout. https://t.co/YRiVuOKof4
10 Jun 2015 Social Efficacy of Anakinra in Crystal synovitis. Complete improvement is seen in 3-5 days http://t.co/oTmnycx9m1
01 Dec 2016 Social Takeda 2 yr study of 314 early #gout pts showed less acute flares w/ Uloric vs PBO (29% v 41%), but not in 1st 6mos. https://t.co/oTCYXyEX6o
07 Aug 2019 Social Prospective study of 83 gout patients; 77 on urate lowering Rx, 6 discontinued Rx. The D/C group had no change in MSU deposits or SUA levels, In the ULT group MSU burden significantly decreased (MSU volume: p=0.007) and sUA dropped from 7.2 to 5,8 mg/dl. https://t.co/YfXjTKz1va
08 Nov 2017 Social RT @WShergy: Low Uric acid may raise the risk of dementia. acr2017 @rheumnow#2080 https://t.co/bBL1mG0Ga7
04 Feb 2016 Social Uricosuric effects are seen with Losartan, Irbesartan, CCB (amlodipine), fenofibrate, vitamin C, coffee, skim milk, yogurt and leflunomide
17 Aug 2015 Social Salivery uric acid levels measureable in gout - more proof that gout is a systemic uric acid deposition disease http://t.co/cA03VMuG39
15 Mar 2017 Social Xrays & DECT in 92 gout pts, tophi and urate assoc w/ 80% of all erosions. Urate, tophus volume predict erosions https://t.co/JlDle82bUx
07 Aug 2018 Social 10 yr study of ~13k US VA gout pts who did/didnt increase allopurinol shows dose escalation seldom achieved target SUA <6.0, but was associated with increased mortality (HR 1.08; 95%CI 1.01–1.17). Escalation more a marker of severity, not T2T https://t.co/NxzhnUfU2M
26 Apr 2016 Social Astra-Zeneca sells the rights to sell gout drug Zurampic (lesinurad) to Ironwood pharmaceutical for $265 million. https://t.co/GXht3lje3s
13 Nov 2019 Social RT @DrKanikaMonga: 2020 Gout Clinical Practice Guideline 42 recommendations (16 strong) - 27 ULT management (13 strong) - 5 Gout Flares (3…
26 Oct 2015 Social 75 pts >50 yrs w knee effusions were studied:Ultrasound was more sensitive(60 v 40%) & specific (97 v 83%) than Xray https://t.co/dKr2BbZphN
27 Oct 2017 Social RheumNow Wk in Review is up! Cush on gout, CV risk, Biosimilars,FDA approvals.Vid or podcast https://t.co/UJHqRBPPGo https://t.co/MYf4CnCWOR
29 Mar 2018 Social Who was the 5th Beatle?
15 Jul 2016 Social Comic strips? Annals IM has one, Price of Progress", cost of colchicine , falls, CNS bleeds, hospitals. So pathetic https://t.co/HlEPDYYrkj
06 Jun 2019 Social The overall prevalence of gout among US adults is 3.9%, affecting 9.2 million people. Hyperuricaemia prevalence is 14.6% - affecting 32.5 million in the US. Data from NHANES NHANES 2015–16 https://t.co/3g05GmUDUA
06 Nov 2017 Social RT @Janetbirdope: #GAMECHANGERS If you have gout and typeII diabetes you have worse gout. More tophi and erosions. #acr17 @rheumnow #1118…