Friday, 18 Oct 2019

Gout/Crystal

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23 Oct 2015 Social FDA Arthritis Advisory Committee votes 10-4 in favor of Lesinurad (+XOI) for hyperuricemia/gout; despite safety concerns over renal effects
21 Sep 2016 Social Nurses Health Study shows women w/ gout have 38% increased risk hip fractures. https://t.co/MxZeMA5Tho
06 Nov 2017 Social RT @KDAO2011: Dr D Solomon #ACR17 @rheumnow YR in Review DASH diet (see photo) decrease gout risk https://t.co/rNWszhrAD9 https://t.co/PKCP…
03 Feb 2016 Social Methotrexate had no benefit in a small crossover trial in pts w/ chronic Calcium Pyrophosphate Deposition Disease https://t.co/MZwe8DmAPK
23 Feb 2018 Social RT @ARD_BMJ: Large study reveals the relationship between serum urate concentrations & clinically evident incident #gout. 15-year cumulativ…
07 Apr 2016 Social Magnitude of visceral fat and liver fat loads are independently associated with hyperuricemia. https://t.co/bjplIDJAHz
18 Jun 2019 Social RT @GoutGroup: #Gout and #genetics at #EULAR2019. New data on genes linked to sUA regulation and leading-edge genetics on conversion from #…
30 Jul 2015 Social High risk CHF pts w/ hyperuricemia- treatment w/ allopurinol failed to improve outcomes, QOL, ejection fraction http://t.co/Z6H0MaKZYi
25 May 2016 Social Allopurinol: (100-800 mg/d);Monitor CBC, LFTs, Creat, Eos. Serious interaction w/ AZA & 6MP. EtOH decreases effect https://t.co/8232u3pZDN
15 Sep 2018 Social Gout is associated with a higher risk of hearing loss in older adults, A 5% random sample of Medicare 2006–2012, shows incidence hearing impairment to be higher in people with gout (16.9 vs. non-gout 8.7 per 1000PY). HR=1.44 https://t.co/mD9ihPcPVh
31 Jul 2019 Social NHANES analysis shows that higher serum uric acid (SUA) levels had a greater risk of coronary heart disease and stroke mortality (mainly women >50 years); but there was no link between SUA and all-cause and cancer mortality. https://t.co/UGNSiKsjQl
05 Oct 2015 Social OMERACT defines Ultrasound elementary lesions for #Gout; double contour sign, tophus, aggregates, & erosions http://t.co/hxW00Vvrjv
05 Nov 2017 Social RT @DrRachelTate: Double contour sign - earliest sign of uric acid deposition obs in asymptomatic gout pts. #ACR17 @RheumNow #250 https://t…
23 Oct 2018 Social RT @CCalabreseDO: prevalence of gout in the hip may be underestimated, as shown in abstract #2240 by use of ultrasound @RheumNow #ACR18
19 Nov 2015 Social As much as I dislike colchicine; results show colchicine in gout nets 49% lower CV & 73% less all-cause mortality https://t.co/EwRUC8RFS0
25 Oct 2016 Social Metanalysis 3 RCTs shows starting allopurinol during acute gout attack does not increase pain or prolong attack. https://t.co/XU6CQxBTNU
07 Nov 2017 Social RT @WIRheum: Allopurinol vs Febuxostat in Dementia. Yes you read that right! Jas Singh et al abs 2076 #ACR17 @RheumNow https://t.co/2SPTrNK…
08 Jan 2018 Social Estimates suggest 8.3 million Gout pts in US; Another recent market estimates claims that worldwide 2016, there were 34.0 million prevalent cases of gout and forecasts and increase to 37.9 million by 2025. https://t.co/U868kzdvug
27 Dec 2016 Social Takeda 2 yr study of 314 early #gout pts showed less acute flares w/ Uloric vs PBO (29% v 41%), but not in 1st 6mos. https://t.co/0537UXnZG7
29 May 2019 Social Risk factors for gouty tophi that ulcerate include: glucocorticoid overuse, tophi duration, and the number of tophi. Based on a chinese study of 105 tophaceous patients of whom 33 developed ulcerations https://t.co/rzYTFCb5jk