Wednesday, 16 Oct 2019


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13 Feb 2019 Social Genetic study using Mendelian randomization methods in a large UK biobank shows that whereas serum Uric acid has no association with eGFR level nor CKD risk, sUA does show a significant risk of #Gout.
04 Mar 2018 Social RheumNow Wk in Review is up. Cool stuff on FDG PET in Lg Vessel vasculitis, gout Rx, nutraceuticals in OA. Listen here ht tps:// or watch it on website
17 Aug 2015 Social Salivery uric acid levels measureable in gout - more proof that gout is a systemic uric acid deposition disease
15 Mar 2017 Social Xrays & DECT in 92 gout pts, tophi and urate assoc w/ 80% of all erosions. Urate, tophus volume predict erosions
11 Jun 2016 Social 1,280 gout compared to 1,231 OA pts; gout had more CVD risk factors, hypertension, ^lipids, CKD but not more MI.
13 May 2018 Social RT @GoutSolution: Immunosuppressive drugs ciclosporin and tacrolimus are also associated with #gout, especially the former combined with hy…
07 Aug 2018 Social 10 yr study of ~13k US VA gout pts who did/didnt increase allopurinol shows dose escalation seldom achieved target SUA <6.0, but was associated with increased mortality (HR 1.08; 95%CI 1.01–1.17). Escalation more a marker of severity, not T2T
16 Jun 2018 Social Abstract Sat 0356 showed pegloticase results in rapid resolution of tophus in bio chemical responders but is not influenced by age gender, race, BMI, tophus location. #EULAR
04 Dec 2015 Social Prudent diet lowers risk of RA & gout, but a big Mac Western diet increases risk of RA & gout. Data from #ACR15
16 May 2019 Social Medicare analysis shows Gout patients are twice as likely to have chronic pain (HR 2.02; 95% CI 1.98-2.05) and use of allopurinol or febuxostat was associated with a lower risk of chronic pain (HR 0.72-0.79)
06 Nov 2017 Social RT @KDAO2011: Risk for CV events lower in new start probenecid (rather than allopurinol) for older >65 yo pts #ACR17 @rheumnow #159 https:/…
06 Nov 2017 Social RT @Janetbirdope: #GAMECHANGERS If you have gout and typeII diabetes you have worse gout. More tophi and erosions. #acr17 @rheumnow #1118…
09 May 2015 Social Review of Losartan shows its uricosuric, can lower Uric acid ~1.6 mg/dl & may be useful in HTN w/ hyperuricemia
16 Mar 2016 Social In a 6 mos RCT, Febuxostat slows the decline in GFR in CKD stages 3/4 compared to placebo.
09 Feb 2018 Social RT @uptoTate: Distinctive differences between gout and cppd on US. Dr. O. Troum and Dr. A. Wells. #RWCS @RheumNow
02 Feb 2017 Social Risk of incident gout 70 fold higher w/ SUA >10; Risk of recurrent gout is 5 fold higher if SUA >9;
10 May 2016 Social Population (34K) based Taiwan study shows gout assoc w/ higher risk of depression; that is normalized w/ pred or ULT
29 Mar 2018 Social Who was the 5th Beatle?
16 May 2017 Social Drug induced hyperuricemia: Diuretics, EMB, PZA, ASA, CyA, fructose, nicotinic acid, Xylitol, lactate, cytotoxics
15 Jul 2016 Social Comic strips? Annals IM has one, Price of Progress", cost of colchicine , falls, CNS bleeds, hospitals. So pathetic