Monday, 26 Aug 2019


Date Typesort descending Title Save
10 Jun 2015 Social Efficacy of Anakinra in Crystal synovitis. Complete improvement is seen in 3-5 days
01 Dec 2016 Social Takeda 2 yr study of 314 early #gout pts showed less acute flares w/ Uloric vs PBO (29% v 41%), but not in 1st 6mos.
08 Nov 2017 Social RT @WShergy: Low Uric acid may raise the risk of dementia. acr2017 @rheumnow#2080
04 Feb 2016 Social Uricosuric effects are seen with Losartan, Irbesartan, CCB (amlodipine), fenofibrate, vitamin C, coffee, skim milk, yogurt and leflunomide
17 Aug 2015 Social Salivery uric acid levels measureable in gout - more proof that gout is a systemic uric acid deposition disease
15 Mar 2017 Social Xrays & DECT in 92 gout pts, tophi and urate assoc w/ 80% of all erosions. Urate, tophus volume predict erosions
07 Aug 2018 Social 10 yr study of ~13k US VA gout pts who did/didnt increase allopurinol shows dose escalation seldom achieved target SUA <6.0, but was associated with increased mortality (HR 1.08; 95%CI 1.01–1.17). Escalation more a marker of severity, not T2T
26 Apr 2016 Social Astra-Zeneca sells the rights to sell gout drug Zurampic (lesinurad) to Ironwood pharmaceutical for $265 million.
26 Oct 2015 Social 75 pts >50 yrs w knee effusions were studied:Ultrasound was more sensitive(60 v 40%) & specific (97 v 83%) than Xray
27 Oct 2017 Social RheumNow Wk in Review is up! Cush on gout, CV risk, Biosimilars,FDA approvals.Vid or podcast
06 Jun 2019 Social The overall prevalence of gout among US adults is 3.9%, affecting 9.2 million people. Hyperuricaemia prevalence is 14.6% - affecting 32.5 million in the US. Data from NHANES NHANES 2015–16
29 Mar 2018 Social Who was the 5th Beatle?
15 Jul 2016 Social Comic strips? Annals IM has one, Price of Progress", cost of colchicine , falls, CNS bleeds, hospitals. So pathetic
06 Nov 2017 Social RT @Janetbirdope: #GAMECHANGERS If you have gout and typeII diabetes you have worse gout. More tophi and erosions. #acr17 @rheumnow #1118…
22 Sep 2016 Social #Gout & anti-HTN meds: diuretics, ꞵ-blockers, α-1 blockers signif increase uric acid levels. No effect w/ CCB, ACEI
09 May 2015 Social Review of Losartan shows its uricosuric, can lower Uric acid ~1.6 mg/dl & may be useful in HTN w/ hyperuricemia
02 Feb 2017 Social Risk of incident gout 70 fold higher w/ SUA >10; Risk of recurrent gout is 5 fold higher if SUA >9;
16 Mar 2016 Social In a 6 mos RCT, Febuxostat slows the decline in GFR in CKD stages 3/4 compared to placebo.
16 May 2017 Social Drug induced hyperuricemia: Diuretics, EMB, PZA, ASA, CyA, fructose, nicotinic acid, Xylitol, lactate, cytotoxics
09 Feb 2018 Social RT @uptoTate: Distinctive differences between gout and cppd on US. Dr. O. Troum and Dr. A. Wells. #RWCS @RheumNow