Wednesday, 13 Dec 2017


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25 May 2017 Social β-Defensin2 is a biomarker reflects IL-17A-driven skin dz in psoriasis, not PsA. Highly correlates w/ PASI & IL-17A
25 May 2017 Social Tight control (TC) trial in PsA (TiCOPA) shows that TC is twice costly & QALYs- not cost-effective in most analyses
24 May 2017 Social European CHMP Recommends Brodalumab (Kyntheum) for use in Plaque Psoriasis. EMA decision awaited.
18 May 2017 Social Hidradenitis suppurativa is uncommon, not rare, prevalence 98/100K, higher in women, age 30-39yr, blacks or biracial
15 May 2017 Social British Society for Rheum 2017 mtg reports smoking is associated w/ more severe AS; data from BSRBR registry for AS
12 May 2017 Social Prevalence of PsA increasing (7.3 in 1997 to 27.3/100k PY 2010), higher in women, w/ increasing DMARD, biologic use
11 May 2017 News Adalimumab Effective in Pediatric Plaque Psoriasis
09 May 2017 News Above-Label Dosing and Noncompliance with Biologics in Psoriatic Arthritis
07 May 2017 Social Pfizer submitted tofacitinib NDA to FDA for psoriatic arthritis. FDA prev denied the NDA for psoriasis w/ CR letter.
02 May 2017 Social 99FM pts had MRI sacroiliitis 8% & met AxSpA criteria 10%. But no control group comparison? Can AS masquerade as FM?
01 May 2017 News Smoking and Worse Outcomes in Spondylitis
30 Apr 2017 Social RT @DrRachelTate: CXCL10 potential biomarker for PsA development in PsO pts. Arthur Kavanaugh, MD and Eric Ruderman, MD #rwcs2017 @RWCSmtg…
30 Apr 2017 Social RT @DrRachelTate: 2016 ASAS-EULAR tx recs in axSpA. #rwcs2017 @RWCSmtg @RheumNow
27 Apr 2017 Social 136 pt study; Flares in pregnancy seen in 29% RA & 25% axSpA, 3fold risk if TNFi stopd. Flares mostly Rx w/ Steroids
25 Apr 2017 Social Study of 1020 LBP pts shows MRI inflammation of the SI was significantly but weakly assoc w/ Inflammatory LBP
21 Apr 2017 Social Valeant prices new Psoriasis drug Siliq (brodalumab) at $42,000/yr. undercutting price of other IL-17 drugs.
19 Apr 2017 News Inconsistent ESR & CRP in Spondylitis Patients
18 Apr 2017 Social Corrona study 1,567 PsA shows patients w/ dactylitis or enthesitis had more Dz activity, Pain, Fatigue, low work,HAQ
07 Apr 2017 Social Dr Ritchlin Risk factors for PsA: obesity, nail dystrophy, smoking, severe psoriasis, nail dystrophy, trauma, Fam Hx PsA,Rubella vaccination
07 Apr 2017 Social Dr. Ritchlin-30% psoriasis pts develop PsA, mechanisms unknown. enthesitis driven by biomechanical factors, arthritis involves IL-17, IL-23