Wednesday, 13 Dec 2017

PsA/SpA

Datesort ascending Type Title Save
25 May 2017 Social β-Defensin2 is a biomarker reflects IL-17A-driven skin dz in psoriasis, not PsA. Highly correlates w/ PASI & IL-17A https://t.co/JmCmMIN0Cq
25 May 2017 Social Tight control (TC) trial in PsA (TiCOPA) shows that TC is twice costly & QALYs- not cost-effective in most analyses https://t.co/MxFR1wjl8N
24 May 2017 Social European CHMP Recommends Brodalumab (Kyntheum) for use in Plaque Psoriasis. EMA decision awaited. https://t.co/q1SJkDKKN5
18 May 2017 Social Hidradenitis suppurativa is uncommon, not rare, prevalence 98/100K, higher in women, age 30-39yr, blacks or biracial https://t.co/XCFE14XDgj
15 May 2017 Social British Society for Rheum 2017 mtg reports smoking is associated w/ more severe AS; data from BSRBR registry for AS https://t.co/QvZ0X73ODp
12 May 2017 Social Prevalence of PsA increasing (7.3 in 1997 to 27.3/100k PY 2010), higher in women, w/ increasing DMARD, biologic use https://t.co/JuT8UpNAEk
11 May 2017 News Adalimumab Effective in Pediatric Plaque Psoriasis
09 May 2017 News Above-Label Dosing and Noncompliance with Biologics in Psoriatic Arthritis
07 May 2017 Social Pfizer submitted tofacitinib NDA to FDA for psoriatic arthritis. FDA prev denied the NDA for psoriasis w/ CR letter. https://t.co/1EMk9QsW3V
02 May 2017 Social 99FM pts had MRI sacroiliitis 8% & met AxSpA criteria 10%. But no control group comparison? Can AS masquerade as FM? https://t.co/PkH4t3CKGh
01 May 2017 News Smoking and Worse Outcomes in Spondylitis
30 Apr 2017 Social RT @DrRachelTate: CXCL10 potential biomarker for PsA development in PsO pts. Arthur Kavanaugh, MD and Eric Ruderman, MD #rwcs2017 @RWCSmtg…
30 Apr 2017 Social RT @DrRachelTate: 2016 ASAS-EULAR tx recs in axSpA. #rwcs2017 @RWCSmtg @RheumNow https://t.co/yuDJyLq9sQ
27 Apr 2017 Social 136 pt study; Flares in pregnancy seen in 29% RA & 25% axSpA, 3fold risk if TNFi stopd. Flares mostly Rx w/ Steroids https://t.co/LSapELP240
25 Apr 2017 Social Study of 1020 LBP pts shows MRI inflammation of the SI was significantly but weakly assoc w/ Inflammatory LBP https://t.co/VOTIszxMPu
21 Apr 2017 Social Valeant prices new Psoriasis drug Siliq (brodalumab) at $42,000/yr. undercutting price of other IL-17 drugs. https://t.co/mfu0ZWWkvv
19 Apr 2017 News Inconsistent ESR & CRP in Spondylitis Patients
18 Apr 2017 Social Corrona study 1,567 PsA shows patients w/ dactylitis or enthesitis had more Dz activity, Pain, Fatigue, low work,HAQ https://t.co/2UcTOZKhYf
07 Apr 2017 Social Dr Ritchlin Risk factors for PsA: obesity, nail dystrophy, smoking, severe psoriasis, nail dystrophy, trauma, Fam Hx PsA,Rubella vaccination
07 Apr 2017 Social Dr. Ritchlin-30% psoriasis pts develop PsA, mechanisms unknown. enthesitis driven by biomechanical factors, arthritis involves IL-17, IL-23