Friday, 20 Apr 2018

RA/Inflammatory arthritis

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19 Apr 2018 News Shared Epitope - Smoking Pathogenic Link Clarified
17 Apr 2018 News Kineret Approved for Still's Disease in EU
16 Apr 2018 Social 2996 HIV+ patients on HRT finds 113 w/ Rheumatic disease, lead by AVN 39 (1.3%), psoriasis 28 (1%), RA 7, PsA 6, & SLE 6pts. HIV Males 1.7 times more likely to have a rheum Dz. Hep C incr the risk of RD. RD Risk in HIV+ appears same as gen population. https://t.co/32PiLEeKgI
13 Apr 2018 News Mayo and UAB Awarded $1 million Grant for Patient Research
12 Apr 2018 Social In a historical prospective cohort study, PPI use in RA (1:4) was associated with a doubling of risk for acute kidney injury (HZ 2.30: 1.26-4.20) but was only 2.2 AKI per 1000PY in RA/PPI+ vs 0.9/1000PY in RA without PPI. Thus depends on need for PPI https://t.co/TxqjAR7Y5Y
09 Apr 2018 News Defining Refractory Rheumatoid Arthritis
09 Apr 2018 Social New RheumNow Survey on the risk of Venous-Thromboembolic Events in RA - Rheums vote here: (VTE is usually due to?) https://t.co/rmilEeZthL
09 Apr 2018 Social Abbvie announces results of its JAK inhibitor upadacitinib ouperforming adalimumab with ACR20 71%, ACR50 of 45%, 29 DAS remission, LDAS 45% at week 12 https://t.co/4bQ6FOkLhc
08 Apr 2018 Social 56 myositis patients with anti‐NXP‐2 autoantibodies (18 with and 38 without calcinosis) showed that NXP‐2 Ab levels correlate w/ disease activity, espcially in those without calcinosis; suggesting calcinosis defines 2 phenotypes. https://t.co/oxtpwUbtJv
06 Apr 2018 Social RheumNow Wk in Review is up! The Temporal Artery Biopsy Letdown! Listen https://t.co/HXSTSfAwlX or watch on the website https://t.co/WN6VYQwSQp
06 Apr 2018 News Uveitis in JIA: Screen All, Treat Early
05 Apr 2018 Social Swiss study of 244 pregnancies finds RA and axSpA have significantly higher risk of pregnancy complications (DM, preeclampsia, infection, small babies, preterm delivery). Active disease predicts preterm delivery in both RA (OR 3.9) & axSpA (OR 13.8) https://t.co/I02unIG499
05 Apr 2018 Social EMR study of 116 obese/overweight RA clinic pts shows that the 31% lost ≥5 kg during follow-up had 3 fold chance of disease activity improvement (CDA >5). https://t.co/JIanV3FuE8
05 Apr 2018 Social 2 RA Cohorts compared 1996 (T1) & 2006 (T2). Total cost of care similar from T1 to T2 (EUR 13280 v 12342), Dz activity, sick leave & hospitalization decreased, yet DMARD & drug cost increased. Loss of productivity is the largest part of total costs. https://t.co/OuIyQwGSjv
03 Apr 2018 Social RT @KearsleyFleet: #publicationanniversary Looking back to the @BSRBR_RA publication from last year: "Rates of live births were reassuring…
03 Apr 2018 Social 3 million have IBD in USA. New study of 22 million IBD pts shows a 2 fold greater risk of MI (5.9% vs 3.5% without IBD). https://t.co/UACAiTfAAt
03 Apr 2018 Social RT @jrheum: Ocular Involvement in Sarcoidosis https://t.co/4QnuHZ1lX2 #sarcoidosis #eye #vision https://t.co/ml3RXpysyE
03 Apr 2018 Social Claims analyses from Medicare, IMS PharMetrics & MarketScan (2010-15) looked at CV outcomes in RA pts starting tocilizumab (6,237) or abatacept (14,685) & finds no difference in CV risk (HR 0.82; 0.55–1.22) (TCZ vs ABA) https://t.co/jNnOCDvX2u
02 Apr 2018 Social 56 myositis patients with anti‐NXP‐2 autoantibodies (18 with and 38 without calcinosis) showed that NXP‐2 Ab levels correlate w/ disease activity, espcially in those without calcinosis; suggesting calcinosis defines 2 phenotypes. https://t.co/1BhJeWTMgv
02 Apr 2018 Social UK study of 2386 early RA patients showed Obesity prevalence is rising and is linked to worse disease activity, function, HRQOL. The data argue strongly for obesity management to be integrated into RA care https://t.co/ZEVSKDcBon