Thursday, 21 Mar 2019

RA/Inflammatory arthritis

Datesort ascending Type Title Save
16 Mar 2019 Social Daily noninvasive ultrasound (US) stimulation of the spleen significantly reduces disease severity in a murine model of inflammatory arthritis. Results mediated via T & B cell effects as T/B deficient mice did not improve with splenic US.
15 Mar 2019 ACR Video QD Clinic - The Power of Patient Choice
07 Mar 2019 News Multiple Delays in Referral of New RA Patients
07 Mar 2019 Social Claims analysis from Natl Taiwan Health Database, compared 262 JIA pts w/ controls & showed JIA pts have 30 fold higher risk of an adult autoimmune dz- Hazard Ratio=129.5 for RA; aHR-10.1 SLE, 49.62 AS & 8.2 PsA. Highest risk (46x) for JIA onset 11-15 yrs
07 Mar 2019 Social Rule of thumb on VTE risks: Normal population 0-.4/100PYs; RA patients are increased at 0.3-0.7/100 PY. If a new RA drug were to cause VTE (venous thromboembolic events; DVT/PE) it would have to have a rate consistently higher than 0.5 and probably higher than 0.7/100PY
07 Mar 2019 Social The PARA study shows among 249 pregnancies (2002-2008), breastfeading was less in RA - at 4-6, 12 & 26 wks postpartum 43%, 26% and 9% of the RA breastfed (vs 63%, 46% & 41% in controls). Many patients D/C breastfeeding so they could start medication.
06 Mar 2019 Social From CreakyJoints- 20 Things pts wish their Rheums Knew: 1 Fix the Vocab, 2 Dont rush me, 3 Dont sugarcoat, 4 Realistic diet, 5 Listen to me, 6 Dont judge me, 7 Flares last longer than you think, 8 Do a mental check up; AND MORE
05 Mar 2019 ACR Video QD Clinic - When it’s not Rheumatoid Arthritis
04 Mar 2019 Social QD Clinic from RheumNow - what to think and expect with Pregnancy and Dermatomyositis
04 Mar 2019 Social Differential Dx of Parotitis - Infection,Mumps, HIV, Sjogrens, Sarcoidosis, Lymphoma, juvenile recurrent parotitis, drugs (l-asparaginase, clozapine, and phenylbutazone)
03 Mar 2019 Social QD Clinic - Rheumatoid Cachexia | RheumNow -80 lb weight loss in RA
01 Mar 2019 Social Rock Star Peter Frampton (Frampton Comes Alive 1976) recently revealed he has Inclusion Body Myositis. Diagnosed 4 yrs ago when he noted weakness in his arms. Now on a big tour to raise funds for the Peter Frampton Myositis Research Fund at Johns Hopkins
28 Feb 2019 ACR Video QD Clinic - Rheumatoid Cachexia
28 Feb 2019 Social Population cross sectional study from Israel analyzed 11,782 RA pts and 57,973 controls. Thyroid disease was increased in RA patients vs controls (16.0% v 11.7%, p < 0.001 HypoT4; OR = 1.42, 95% CI 1.34–1.50) and hyperthyroidism (OR = 1.26).
27 Feb 2019 Social Key features in distinguishing Adult onset Stills disease from Fever of unknown origin: Arthralgia, rash, sore throat, neutrophilia, ferritin >5xULN, LDH based on comparison study of 69 AOSD & 87 FUO pts. 3 or more fever peaks daily makes AOSD less likely.
26 Feb 2019 Social Nurses Health Study had 1528 incident #RA cases. Current smoking increased risk of seropositive (not Seronegative) RA (HR 1.47). Smoking cessation >10, >20, >30 yrs ago assoc w/ decreasing risk of seropos. RA, but risk still remains > 30 yrs (HR 1.30)
26 Feb 2019 News Does Smoking Cessation Reduce RA Risk?
21 Feb 2019 ACR Video QD Clinic - Change in DMARD or Not
21 Feb 2019 Social QD Clinic - The NP Says the Patient is Flaring | RA patient is Flaring with interruption of Abatacept; the NP want to know what to do.
20 Feb 2019 Social Swedish Population study shows a 2 fold higher mortality in patients with RA and MSK (SMR 2.2 & 1.5) patients with < 9 years of education compared with those with > 12 years of education.