Wednesday, 16 Oct 2019

RA/Inflammatory arthritis

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09 Oct 2015 Social Genetic basis for pediatric autoimmune disease finds greatest associations with type I DM & JIA, modest for UC & CD
27 Dec 2017 Social Nice Review of the Treatment of idiopathic Inflammatory Myopathies by Parker and Chinoy @drhectorchinoy; Covers MTX, AZA, IVIG, CTX, RTX, calcineurin inhib & biologics. Full text from European Medical Journal.
02 Apr 2018 Social 56 myositis patients with anti‐NXP‐2 autoantibodies (18 with and 38 without calcinosis) showed that NXP‐2 Ab levels correlate w/ disease activity, espcially in those without calcinosis; suggesting calcinosis defines 2 phenotypes.
23 Aug 2019 Social RheumNow Podcast is up! Upadacitinib Approved, ULT prevents erosions, JIA pregnancies, MDA-5 outcomes & more. Watch it here>> or listen to the PODCAST on iTunes or SoundCloud>>
15 May 2018 Social RA pts have a greater risk of CVA; Study of 7904 RA pts shows that short-term methotrexate might decrease ischemic stroke risk, but hydroxychloroquine and sulfasalazine did not.
06 Apr 2017 Social Dr McInnes - RA pathogenesis focused on the macrophage via interactions with Tcells, ICs, DAMPs, Proteases, Oxysterols, Cytokines, MICL Abs
24 Oct 2018 Social RT @samwhittle: 2018 Great Debate examines questions about hydroxychloroquine dosing guidelines
19 Feb 2016 Social Dr Jeff Curtis analyzes why some patients dont/wont do #T2T & maybe how to best frame the need for T2T in RA
23 May 2017 Social My Approach to Difficult RA, some different thoughts/approaches, 7 drugs you've never used and more
02 Aug 2016 Social TEAR had significantly improved RA activity assoc w/ increased cholesterol, HDL, LDL w/ MTX, MTX/ETN, triple DMARD
09 Dec 2016 Social RT @CCalabreseDO: Wide spectrum of joint manifestations seen post-Chikungunya infection @RheumNow @LCalabreseDO
05 Nov 2017 Social RT @_connectedcare: A reminder how common malignancy is with dermatomyositis #ACR17 @rheumnow
28 Jul 2019 Social Im starting a War on RA. I need you go get mad and do your part. Read 1st of 4 part series or watch it here
13 Dec 2018 Social No differences seen in the rates of major adverse CV events (MACE) between RA, axial SpA or PsA pts, suggesting inflammation, rather than a disease, drives CV risk. Data from a Swiss mixed retrospective/prospective cohort study
02 Jul 2018 Social Australian RCT - Trochanteric bursitis (glueal tendinopathy) Rx w/ either education + exercise (EDX), steroid injx or "wait & see". EDX wins w/ better pain and global scores at wk 8 & better global scores at wk 52 (still less pain)
16 Apr 2018 Social 2996 HIV+ patients on HRT finds 113 w/ Rheumatic disease, lead by AVN 39 (1.3%), psoriasis 28 (1%), RA 7, PsA 6, & SLE 6pts. HIV Males 1.7 times more likely to have a rheum Dz. Hep C incr the risk of RD. RD Risk in HIV+ appears same as gen population.
30 May 2018 Social 5 Yr study of 403 early RA patients shows radiographic progression occurred in 143 (35.5%), more likely with high dose steroids and less likely with >36 mos of biologic therapy.
16 Mar 2019 Social Daily noninvasive ultrasound (US) stimulation of the spleen significantly reduces disease severity in a murine model of inflammatory arthritis. Results mediated via T & B cell effects as T/B deficient mice did not improve with splenic US.
27 Jul 2015 Social RT @DrPetryna Nationwide Taiwan cohort study identifies chronic osteomyelitis as a risk factor for development of RA
14 Nov 2018 Social CCP+ RA patient starts out with 8 tender, 6 swollen and DAS=5.1. Put on MTX and TNFi and quickly goes into remission (0 joints) at month 6, 12, 18. At next visit what do you do w/ meds?