Friday, 13 Dec 2019

RA/Inflammatory arthritis

Date Typesort ascending Title Save
24 Feb 2017 Social ?Which of following most influences risk of getting #RA? A) 1st degree relative w/ RA; B) RF 34 IU; C) CCP >250 IU; D) CarbP Ab+ (answer=C)
18 Aug 2016 Social Comprehensive overview explores range of microbes as the cause of rheumatoid arthritis
22 May 2017 Social Multi-Morbidity is quite common in RA (25%) and correlates with disease activity (HAQ, Pt global assessment)…
12 Sep 2017 Social IL-6/Th17/IL-17 drives systemic inflam, while IL-12/Th1/IFN-γ drives vascular inflam, in TAK & giant cell arteritis
06 Nov 2017 Social RT @_connectedcare: Bingham: “birth & genesis of a completely new disease” - checkpoint inhibitor-induced rheumatic disease #ACR17 @rheumnow
11 Jan 2018 Social Metanalysis of #RA cost of care (12 papers, only1/3 good) -Tot direct medical costs ~ $12,509 for all RA pts; $36,053 for bDMARD users; RA-specific costs were $3,723 all RA patients and $20K for bDMARD users
09 Apr 2018 Social New RheumNow Survey on the risk of Venous-Thromboembolic Events in RA - Rheums vote here: (VTE is usually due to?)
14 Jun 2018 Social RT @Janetbirdope: Lessons learned from Day 1. RA has increased mortality but less than previously. 2. Check Point Inhibitors increase autoi…
14 Feb 2019 Social Small study of 25 pregnancies in RA compared those who continued biologics till conception vs those who stopped before conception. Continuing biologics till conception lead to a significantly shorter time to pregnancy.
15 May 2019 Social Reactivation of latent CMV infection is rare in Rheum Pts. 14 pts described w/ febrile illness, on steroids (13), with coinfections (8), 4 died during hospitalization, tend to have longer hospitalizations (47 vs. 7 days), more coinfections (67% vs. 17%)
06 Aug 2019 Social Metanalysis of 9 studies shows that use of IVIG in ANCA-Associated vasculitis is assoc. w/ significant and rapid improvement in BVAS (SMD –1.7), ANCA (SMD –0.72) and CRP (SMD –0.92) within 2-24 weeks.
11 Oct 2019 Social FDA grants breakthrough status to OFEV (nintedanib) forthe treatment of chronic fibrosing interstitial lung diseases (ILDs), other than idiopathic pulmonary fibrosis (which it is currently approved for). Nintedanib has been studied in PSS ILD.
07 Dec 2016 Social Genes/SNPs that influence RA onset/risk are not predictive of drug responses or ultimate outcomes
21 Jun 2015 Social Varicella Zoster Virus Commonly Found in Giant Cell Artery Biopsies | RheumNow - Rheumatology News & Information
10 Mar 2016 Social Collagen induced arthritis worse w/ serotonin deficit: incr TNF, IL-17, Th-17 cells; improved by 5-HT recept agonist
06 Oct 2015 Social On death certificates RA not a listed cause in 80%; most attributed to comorbidity."RA" likely w/ young, deformities
30 Dec 2016 Social Incident RA prevalence=0.63%; 2/3 Rx w/ DMARD, but 28% were not. 38% @1yr & 15% @2yr never seen by Rheumatologist
05 Apr 2017 Social Studies showing cognitive impairment in #RA - probs w/ verbal, memory, attention. worse w/ age, depression, activity
27 May 2016 Social Age & Smoking enhance risk of periodontitis; but no increased prevalence of periodontitis in established RA
24 Apr 2017 Social Sequencing 750 genes in 1,094 RA pts fails to identify genes correlating w/ TNFi resp or Dz activity; biomarker bust